2019 Vol. 37, No. 4
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2019, 37(4): 289-293.
doi: 10.3969/j.issn.1006-0111.2019.04.001
Abstract:
Isoniazid(INH) is one of the most important drugs for the prevention and treatment of tuberculosis,and is the first choice for the four major first-line anti-tuberculosis drugs.A series of studies have shown that isoniazid has hepatotoxicity,and the ...
Isoniazid(INH) is one of the most important drugs for the prevention and treatment of tuberculosis,and is the first choice for the four major first-line anti-tuberculosis drugs.A series of studies have shown that isoniazid has hepatotoxicity,and the ...
2019, 37(4): 294-298.
doi: 10.3969/j.issn.1006-0111.2019.04.002
Abstract:
Objective To study the protective effect and mechanism of anhydrous ethanol extract of areca catechu linn against hypoxia in H9C2 cells. Methods Myocardial cell hypoxic mold was established by H9C2 cell line.The effect of areca catechu linn anhydro...
Objective To study the protective effect and mechanism of anhydrous ethanol extract of areca catechu linn against hypoxia in H9C2 cells. Methods Myocardial cell hypoxic mold was established by H9C2 cell line.The effect of areca catechu linn anhydro...
2019, 37(4): 299-303.
doi: 10.3969/j.issn.1006-0111.2019.04.003
Abstract:
Objective To investigate the protective effect and primary mechanism of Gallic acid on 60Co-γ ray induced Human Intestinal Epithelial cell (HIEC) damage. Methods HIEC in the exponential phase were inoculated in petri dishes and were randomly divide...
Objective To investigate the protective effect and primary mechanism of Gallic acid on 60Co-γ ray induced Human Intestinal Epithelial cell (HIEC) damage. Methods HIEC in the exponential phase were inoculated in petri dishes and were randomly divide...
2019, 37(4): 304-308.
doi: 10.3969/j.issn.1006-0111.2019.04.004
Abstract:
Objective To study the protective effect of Shengxian decoction (SXT) and its each single herb component against doxorubicin induced cardiomyocyte injury. Methods Myocardial cells isolated from the neonatal rats with hypoxia/reoxygenation injury of...
Objective To study the protective effect of Shengxian decoction (SXT) and its each single herb component against doxorubicin induced cardiomyocyte injury. Methods Myocardial cells isolated from the neonatal rats with hypoxia/reoxygenation injury of...
2019, 37(4): 309-313,317.
doi: 10.3969/j.issn.1006-0111.2019.04.005
Abstract:
Objective To investigate the chemical constituents and cytotoxic activities of breast cancer in the roots of Euphorbia ebracteolata. Methods The chemical constituents were isolated and purified by various chromatographic techniques.The in vitro cyt...
Objective To investigate the chemical constituents and cytotoxic activities of breast cancer in the roots of Euphorbia ebracteolata. Methods The chemical constituents were isolated and purified by various chromatographic techniques.The in vitro cyt...
2019, 37(4): 314-317.
doi: 10.3969/j.issn.1006-0111.2019.04.006
Abstract:
Objective To investigate the secondary metabolites of the marine fungi Chaetomium sp. Methods The EtOAc extract of Chaetomium sp.fermentation was purified by repeated column chromatography on silica gel,Sephadex LH-20,and high-performance liquid ch...
Objective To investigate the secondary metabolites of the marine fungi Chaetomium sp. Methods The EtOAc extract of Chaetomium sp.fermentation was purified by repeated column chromatography on silica gel,Sephadex LH-20,and high-performance liquid ch...
2019, 37(4): 318-321.
doi: 10.3969/j.issn.1006-0111.2019.04.007
Abstract:
Objective To investigate the distribution of resources and pharmacognostical characteristics of Abri herba and provide scientific basis for the identification and utilization of Abri herba safely and rationally. Methods Through the literature sear...
Objective To investigate the distribution of resources and pharmacognostical characteristics of Abri herba and provide scientific basis for the identification and utilization of Abri herba safely and rationally. Methods Through the literature sear...
2019, 37(4): 322-331.
doi: 10.3969/j.issn.1006-0111.2019.04.008
Abstract:
Objective To develop a rapid identification method for domestic and imported hops by the establishment of PCA-SVM model using near-infrared reflectance spectroscopy (NIRS),combined with principal component analysis (PCA) and support vector machine (...
Objective To develop a rapid identification method for domestic and imported hops by the establishment of PCA-SVM model using near-infrared reflectance spectroscopy (NIRS),combined with principal component analysis (PCA) and support vector machine (...
2019, 37(4): 332-336.
doi: 10.3969/j.issn.1006-0111.2019.04.009
Abstract:
Objective To evaluate therapeutic effects of Lysimachiae Herba for crystallization kidney injury with serum metabolomics method. Methods 21 rats were randomly divided into three groups including control group,crystallization kidney injury model gro...
Objective To evaluate therapeutic effects of Lysimachiae Herba for crystallization kidney injury with serum metabolomics method. Methods 21 rats were randomly divided into three groups including control group,crystallization kidney injury model gro...
2019, 37(4): 337-341,347.
doi: 10.3969/j.issn.1006-0111.2019.04.010
Abstract:
Objective To establish a method for simultaneous determination of three triterpenoid saponins (BeesiosideⅠ、Ⅱ、Ⅲ),and investigate antioxidant effects of triterpenoid saponin extracted from Bessia calthaefolia. Methods The content assay of triterpenoi...
Objective To establish a method for simultaneous determination of three triterpenoid saponins (BeesiosideⅠ、Ⅱ、Ⅲ),and investigate antioxidant effects of triterpenoid saponin extracted from Bessia calthaefolia. Methods The content assay of triterpenoi...
2019, 37(4): 342-347.
doi: 10.3969/j.issn.1006-0111.2019.04.011
Abstract:
Objective To investigate the effect of triamcinolone acetonide cream (TAC) delivered by microneedle roller on the treatment for human hypertrophic scar. Methods The model was established by xenografting human hypertrophic scar onto the back of nude...
Objective To investigate the effect of triamcinolone acetonide cream (TAC) delivered by microneedle roller on the treatment for human hypertrophic scar. Methods The model was established by xenografting human hypertrophic scar onto the back of nude...
2019, 37(4): 348-351.
doi: 10.3969/j.issn.1006-0111.2019.04.012
Abstract:
Objective To determine the content of α-Asarone in Piper sarmentosum Roxb.from different habitats by HPLC. Methods The chromatographic column was Lichrospher C18 (150 mm×4.6 mm,5μm).The mobile phase was acetonitrile-0.05% H3PO4 solution (47:53) wit...
Objective To determine the content of α-Asarone in Piper sarmentosum Roxb.from different habitats by HPLC. Methods The chromatographic column was Lichrospher C18 (150 mm×4.6 mm,5μm).The mobile phase was acetonitrile-0.05% H3PO4 solution (47:53) wit...
2019, 37(4): 352-356,374.
doi: 10.3969/j.issn.1006-0111.2019.04.013
Abstract:
Objective To establish a method for the determination of the content of total flavonoids in compound Huanglian clysis. Methods Three reference substances and the three coloration methods were studied to find the ideal coloration method and determin...
Objective To establish a method for the determination of the content of total flavonoids in compound Huanglian clysis. Methods Three reference substances and the three coloration methods were studied to find the ideal coloration method and determin...
2019, 37(4): 357-360,369.
doi: 10.3969/j.issn.1006-0111.2019.04.014
Abstract:
Objective To establish a microbial limit test method for compound terbinafine gel. Methods The test was carried out according to the requirements of provision 1105,1106 and 1107 of rules of preparation in volume IV of Chinese pharmacopoeia 2015 edi...
Objective To establish a microbial limit test method for compound terbinafine gel. Methods The test was carried out according to the requirements of provision 1105,1106 and 1107 of rules of preparation in volume IV of Chinese pharmacopoeia 2015 edi...
2019, 37(4): 361-364.
doi: 10.3969/j.issn.1006-0111.2019.04.015
Abstract:
Objective To establish a double wavelength HPLC method for determination of dexamethasone sodium phosphate and ethylparaben in Zhiyang dishuang cream. Methods The HPLC method was adopted with the Wondasil C18(4.6 mm×250 mm,5 μm) and triethylamine s...
Objective To establish a double wavelength HPLC method for determination of dexamethasone sodium phosphate and ethylparaben in Zhiyang dishuang cream. Methods The HPLC method was adopted with the Wondasil C18(4.6 mm×250 mm,5 μm) and triethylamine s...
2019, 37(4): 365-369.
doi: 10.3969/j.issn.1006-0111.2019.04.016
Abstract:
Objective To investigate the pharmacological monitoring in a hepatic abscess patient after radiofrequency ablation for primary hepatocellular carcinoma with type 2 diabetes mellitus. Methods The patient's liver and kidney function were monitored to...
Objective To investigate the pharmacological monitoring in a hepatic abscess patient after radiofrequency ablation for primary hepatocellular carcinoma with type 2 diabetes mellitus. Methods The patient's liver and kidney function were monitored to...
2019, 37(4): 370-374.
doi: 10.3969/j.issn.1006-0111.2019.04.017
Abstract:
Objective To explore clinical pharmacists' role in antithrombotic therapy for acute myocardial infarction (AMI) inpatients with heparin-induced thrombocytopenia (HIT) after percutaneous coronary intervention (PCI). Methods Clinical pharmacists used...
Objective To explore clinical pharmacists' role in antithrombotic therapy for acute myocardial infarction (AMI) inpatients with heparin-induced thrombocytopenia (HIT) after percutaneous coronary intervention (PCI). Methods Clinical pharmacists used...
2019, 37(4): 375-379.
doi: 10.3969/j.issn.1006-0111.2019.04.018
Abstract:
Objective To evaluate the therapeutic effects of magnesium isoglycyrrhizinate in patients with antituberculosis drug-induced liver injury. Methods The literatures related to randomized controlled trials (RCT) of magnesium isoglycyrrhizinate treatme...
Objective To evaluate the therapeutic effects of magnesium isoglycyrrhizinate in patients with antituberculosis drug-induced liver injury. Methods The literatures related to randomized controlled trials (RCT) of magnesium isoglycyrrhizinate treatme...
2019, 37(4): 380-384.
doi: 10.3969/j.issn.1006-0111.2019.04.019
Abstract:
Objective To analyze the utilization of Chinese patent medicines in a hospital outpatient pharmacy in Shanghai and evaluate the effectiveness of measures to control the component ratio of the medications. Methods The sales volume and total cost of ...
Objective To analyze the utilization of Chinese patent medicines in a hospital outpatient pharmacy in Shanghai and evaluate the effectiveness of measures to control the component ratio of the medications. Methods The sales volume and total cost of ...