2019 Vol. 37, No. 3
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2019, 37(3): 193-200,253.
doi: 10.3969/j.issn.1006-0111.2019.03.001
Abstract:
More and more attentions had been paid to the chemical constituents of epiphytic fungi in coral.By the end of 2014,95 species of epiphytic fungi,involving 44 genera,were isolated from 38 coral species.More than 200 compounds were isolated from them.T...
More and more attentions had been paid to the chemical constituents of epiphytic fungi in coral.By the end of 2014,95 species of epiphytic fungi,involving 44 genera,were isolated from 38 coral species.More than 200 compounds were isolated from them.T...
2019, 37(3): 201-205.
doi: 10.3969/j.issn.1006-0111.2019.03.002
Abstract:
Virus infection threatens human health.At present,the existing antiviral drugs have several problems including drug resistance and side effects.Thus,the study of new antiviral drugs has still become an urgent need in clinical practice.In this paper,s...
Virus infection threatens human health.At present,the existing antiviral drugs have several problems including drug resistance and side effects.Thus,the study of new antiviral drugs has still become an urgent need in clinical practice.In this paper,s...
2019, 37(3): 206-211,278.
doi: 10.3969/j.issn.1006-0111.2019.03.003
Abstract:
Dihydroartemisinin(DHA),an important artemisinin derivative,is one of new anti-malarial medicines developed by Chinese scientists.In recent years,it was reported that DHA is a promising anti-cancer medicine besides its extraordinary antimalarial acti...
Dihydroartemisinin(DHA),an important artemisinin derivative,is one of new anti-malarial medicines developed by Chinese scientists.In recent years,it was reported that DHA is a promising anti-cancer medicine besides its extraordinary antimalarial acti...
2019, 37(3): 212-215,221.
doi: 10.3969/j.issn.1006-0111.2019.03.004
Abstract:
Micro gels are functional polymer with intramolecular crosslinked network structure and particle size between 0.1 and 100 μm.Micro gels have the characteristics of small particle size,high drug loading,and good environmental responsiveness and biocom...
Micro gels are functional polymer with intramolecular crosslinked network structure and particle size between 0.1 and 100 μm.Micro gels have the characteristics of small particle size,high drug loading,and good environmental responsiveness and biocom...
2019, 37(3): 216-221.
doi: 10.3969/j.issn.1006-0111.2019.03.005
Abstract:
Objective To investigate effects of different dosages of fungal biofertilizer from Trichoderma atroviride D16 on the growth and secondary metabolism of Salvia miltiorrhiza. Methods S.miltiorrhiza and fungal biofertilizer from T.atroviride D16 were ...
Objective To investigate effects of different dosages of fungal biofertilizer from Trichoderma atroviride D16 on the growth and secondary metabolism of Salvia miltiorrhiza. Methods S.miltiorrhiza and fungal biofertilizer from T.atroviride D16 were ...
2019, 37(3): 222-225.
doi: 10.3969/j.issn.1006-0111.2019.03.006
Abstract:
Objective To optimize the formulation of polyvinyl alcohol-propranolol hydrochloride porous hydrogel by central composite design-response surface method. Methods The amount of polyvinyl alcohol and chitosan were taken as the investigation factors,t...
Objective To optimize the formulation of polyvinyl alcohol-propranolol hydrochloride porous hydrogel by central composite design-response surface method. Methods The amount of polyvinyl alcohol and chitosan were taken as the investigation factors,t...
2019, 37(3): 226-230.
doi: 10.3969/j.issn.1006-0111.2019.03.007
Abstract:
Objective To explore the possible mechanism of total flavonoids from Armeniaca mume(TFAM) through observing its effects on neuroendocrine and oxidative stress of rats with depression induced by chronic mild stress. Methods The SD rats were randomly...
Objective To explore the possible mechanism of total flavonoids from Armeniaca mume(TFAM) through observing its effects on neuroendocrine and oxidative stress of rats with depression induced by chronic mild stress. Methods The SD rats were randomly...
2019, 37(3): 231-236.
doi: 10.3969/j.issn.1006-0111.2019.03.008
Abstract:
Objective To investigate the anti-oxidative effects of the Schisandra chinensis extract in skin cells and develop the application as skin anti-oxidant. Methods The ethanol extraction process of Schisandra chinensis was optimized with hot water pre-...
Objective To investigate the anti-oxidative effects of the Schisandra chinensis extract in skin cells and develop the application as skin anti-oxidant. Methods The ethanol extraction process of Schisandra chinensis was optimized with hot water pre-...
2019, 37(3): 237-240.
doi: 10.3969/j.issn.1006-0111.2019.03.009
Abstract:
Objective To study the role of nicotinamide phosphoribosyltransferase(Nampt)gene in the growth of human embryonic stem cells. Methods CRISPR/Cas9 technology was used for Nampt gene knockout in human embryonic stem cells by introducing frame-shift m...
Objective To study the role of nicotinamide phosphoribosyltransferase(Nampt)gene in the growth of human embryonic stem cells. Methods CRISPR/Cas9 technology was used for Nampt gene knockout in human embryonic stem cells by introducing frame-shift m...
2019, 37(3): 241-245.
doi: 10.3969/j.issn.1006-0111.2019.03.010
Abstract:
Objective To study the therapeutic effects of matrine derivative M19 on type Ⅱcollagen-induced arthritis (CIA) in rats. Methods Sixty rats were randomly divided into six groups:blank group,model group,indomethacin treatment group,M19 low,medium and...
Objective To study the therapeutic effects of matrine derivative M19 on type Ⅱcollagen-induced arthritis (CIA) in rats. Methods Sixty rats were randomly divided into six groups:blank group,model group,indomethacin treatment group,M19 low,medium and...
2019, 37(3): 246-248,259.
doi: 10.3969/j.issn.1006-0111.2019.03.011
Abstract:
Objective To prepare cabazitaxel albumin nanoparticles(CBZ-BSA-Gd-NP) to reduce drug toxicity,and to evaluate its biocompatibility in vitro. Methods CBZ-BSA-Gd-NP was prepared by biomineralization method.The formulation process was optimized,and th...
Objective To prepare cabazitaxel albumin nanoparticles(CBZ-BSA-Gd-NP) to reduce drug toxicity,and to evaluate its biocompatibility in vitro. Methods CBZ-BSA-Gd-NP was prepared by biomineralization method.The formulation process was optimized,and th...
2019, 37(3): 249-253.
doi: 10.3969/j.issn.1006-0111.2019.03.012
Abstract:
Objective To optimized the ethanol extraction process of Ligustrum lucidum Ait. Methods L9(34) orthogonal experiment was adopted with the change of the contents of oleanolic acid,specnuezhenide and extraction yield.The best ethanol extraction proce...
Objective To optimized the ethanol extraction process of Ligustrum lucidum Ait. Methods L9(34) orthogonal experiment was adopted with the change of the contents of oleanolic acid,specnuezhenide and extraction yield.The best ethanol extraction proce...
2019, 37(3): 254-259.
doi: 10.3969/j.issn.1006-0111.2019.03.013
Abstract:
Objective To determine the water absorption coefficient of each individual whole grass Chinese herbal medicine pieces at room temperature,and to guide the water addition in the decoction process of Chinese herbal by the decocting machine. Methods T...
Objective To determine the water absorption coefficient of each individual whole grass Chinese herbal medicine pieces at room temperature,and to guide the water addition in the decoction process of Chinese herbal by the decocting machine. Methods T...
2019, 37(3): 260-265.
doi: 10.3969/j.issn.1006-0111.2019.03.014
Abstract:
Objective To provide advice to further promote the rational use of drugs in children. Methods Bibliometric and visualization methods were used through data mining,information extraction,keyword co-occurrence analysis and other techniques to analyze...
Objective To provide advice to further promote the rational use of drugs in children. Methods Bibliometric and visualization methods were used through data mining,information extraction,keyword co-occurrence analysis and other techniques to analyze...
2019, 37(3): 266-267.
doi: 10.3969/j.issn.1006-0111.2019.03.015
Abstract:
Objective To screen the samples of stronger antagonism to anti-endotoxin in vitro from Ampelopsis radix through a preliminary comparative analysis on before and after processing of Ampelopsis radix. Methods The principle of agglutination produced b...
Objective To screen the samples of stronger antagonism to anti-endotoxin in vitro from Ampelopsis radix through a preliminary comparative analysis on before and after processing of Ampelopsis radix. Methods The principle of agglutination produced b...
2019, 37(3): 268-273.
doi: 10.3969/j.issn.1006-0111.2019.03.016
Abstract:
Objective To explore the effect of clostridium butyricum enterococcus triple viable tablet on the efficacy and adverse reactions of gemcitabine plus platinum(GP) regimen for the patients with advanced non-small cell lung cancer(NSCLC). Methods The ...
Objective To explore the effect of clostridium butyricum enterococcus triple viable tablet on the efficacy and adverse reactions of gemcitabine plus platinum(GP) regimen for the patients with advanced non-small cell lung cancer(NSCLC). Methods The ...
2019, 37(3): 274-278.
doi: 10.3969/j.issn.1006-0111.2019.03.017
Abstract:
Objective To investigate the causes of acute kidney injury in patients with augmented renal clearance during individualized application of vancomycin. Methods Three cases of acute kidney injury caused by vancomycin in our hospital were taken pharma...
Objective To investigate the causes of acute kidney injury in patients with augmented renal clearance during individualized application of vancomycin. Methods Three cases of acute kidney injury caused by vancomycin in our hospital were taken pharma...
2019, 37(3): 279-282.
doi: 10.3969/j.issn.1006-0111.2019.03.018
Abstract:
Objective To explore the key points of pharmaceutical care in patients with thrombocytopenia (HIT) induced by low molecular weight heparin,and to provide reference for clinical pharmacists to participate in the clinical treatment of such patients. M...
Objective To explore the key points of pharmaceutical care in patients with thrombocytopenia (HIT) induced by low molecular weight heparin,and to provide reference for clinical pharmacists to participate in the clinical treatment of such patients. M...
2019, 37(3): 283-288.
doi: 10.3969/j.issn.1006-0111.2019.03.019
Abstract:
Objective To provide reference for clinical pharmacists to promote rational medication use in elderly patients by analyzing the current situation of elderly patients with multiple medication use in nursing institution. Methods A total of 258 elderl...
Objective To provide reference for clinical pharmacists to promote rational medication use in elderly patients by analyzing the current situation of elderly patients with multiple medication use in nursing institution. Methods A total of 258 elderl...
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