2014 Vol. 32, No. 1
Display Method:
2014, 32(1): 1-4,8.
doi: 10.3969/j.issn.1006-0111.2014.01.001
Abstract:
Objective Amphotericin B (AmB) was a polyene antifungal agent. Because of its lowest resistance rate and broad antibiotic spectrum, AmB was considered as a "gold standard" for the treatment of deep fungal infections. However, the occurrence of toxic...
Objective Amphotericin B (AmB) was a polyene antifungal agent. Because of its lowest resistance rate and broad antibiotic spectrum, AmB was considered as a "gold standard" for the treatment of deep fungal infections. However, the occurrence of toxic...
2014, 32(1): 5-8.
doi: 10.3969/j.issn.1006-0111.2014.01.002
Abstract:
Objective To update the application of Caenorhabditis elegans as a model host of infection in anti-infection research field, and provide references for the further application of C. elegans in the research field. Methods The related literatures at...
Objective To update the application of Caenorhabditis elegans as a model host of infection in anti-infection research field, and provide references for the further application of C. elegans in the research field. Methods The related literatures at...
2014, 32(1): 9-15,34.
doi: 10.3969/j.issn.1006-0111.2014.01.003
Abstract:
Computer aided drug design had become part of the drug discovery process, greatly improved the speed of drug development compared with traditional drug finding methods. In particular, the de novo drug design method could be used to identify ligands w...
Computer aided drug design had become part of the drug discovery process, greatly improved the speed of drug development compared with traditional drug finding methods. In particular, the de novo drug design method could be used to identify ligands w...
2014, 32(1): 16-18,22.
doi: 10.3969/j.issn.1006-0111.2014.01.004
Abstract:
Objective To summarize the new dosage forms and new ways to the quality research of Rupixiao in the modern dosage forms. Methods The literatures were reviewed, sorted, and summarized. Results Mostly modern dosage forms of Rupixiao were tablets, c...
Objective To summarize the new dosage forms and new ways to the quality research of Rupixiao in the modern dosage forms. Methods The literatures were reviewed, sorted, and summarized. Results Mostly modern dosage forms of Rupixiao were tablets, c...
2014, 32(1): 19-22.
doi: 10.3969/j.issn.1006-0111.2014.01.005
Abstract:
Magnesium stearate as a lubricant plays an important role in the direct compression of tablet technology, but the use of magnesium stearate often causes negative effect on tablet strength. The reasons of decreasing tablet strength from the aspects of...
Magnesium stearate as a lubricant plays an important role in the direct compression of tablet technology, but the use of magnesium stearate often causes negative effect on tablet strength. The reasons of decreasing tablet strength from the aspects of...
2014, 32(1): 23-26,30.
doi: 10.3969/j.issn.1006-0111.2014.01.006
Abstract:
Objective To compare the effect and safety of the two regimens of topotecan by means of Meta-analysis, in order to give evidences for doctors when selecting regimens. Methods All the studies that have been searched in Pub Med from setup data base ...
Objective To compare the effect and safety of the two regimens of topotecan by means of Meta-analysis, in order to give evidences for doctors when selecting regimens. Methods All the studies that have been searched in Pub Med from setup data base ...
2014, 32(1): 27-30.
doi: 10.3969/j.issn.1006-0111.2014.01.007
Abstract:
Objective To explore the anti-hyperlipidemic effects and mechanism of polysaccharide MA from Mytilus coruscus in the experimental atherosclerosis rabbits and to observe the effects of MA on liver and aorta. Methods The atherosclerosis rabbit model ...
Objective To explore the anti-hyperlipidemic effects and mechanism of polysaccharide MA from Mytilus coruscus in the experimental atherosclerosis rabbits and to observe the effects of MA on liver and aorta. Methods The atherosclerosis rabbit model ...
2014, 32(1): 31-34.
doi: 10.3969/j.issn.1006-0111.2014.01.008
Abstract:
Objective To prepare proanthocyanidins phospholipids complex, investigate the physicochemical properties and study the formulation. Methods Proanthocyanidins phospholipids complex was prepared and optimized by solvent evaporation method and physic...
Objective To prepare proanthocyanidins phospholipids complex, investigate the physicochemical properties and study the formulation. Methods Proanthocyanidins phospholipids complex was prepared and optimized by solvent evaporation method and physic...
2014, 32(1): 35-41,48.
doi: 10.3969/j.issn.1006-0111.2014.01.009
Abstract:
Salvia miltiorrhiza (Bung), a famous medicinal plant, is widely used in China, Japan, America and European countries to treat various conditions, such as cardiovascular and cerebrovascular disease, due to their excellent medicinal values. A novel fru...
Salvia miltiorrhiza (Bung), a famous medicinal plant, is widely used in China, Japan, America and European countries to treat various conditions, such as cardiovascular and cerebrovascular disease, due to their excellent medicinal values. A novel fru...
2014, 32(1): 42-44.
doi: 10.3969/j.issn.1006-0111.2014.01.010
Abstract:
Objective To purify the total flavones from Resina Draconis using D101 resin, and set up a method of simultaneously determining the contents of loureirin A and B in the extract. Methods Fractions in 70% and 95% ethanol were collected. Mixture of a...
Objective To purify the total flavones from Resina Draconis using D101 resin, and set up a method of simultaneously determining the contents of loureirin A and B in the extract. Methods Fractions in 70% and 95% ethanol were collected. Mixture of a...
2014, 32(1): 45-48.
doi: 10.3969/j.issn.1006-0111.2014.01.011
Abstract:
Objective To establish a sensitive and specific LC-MS/MS method for the determination of mitiglinide calcium in human plasma, and investigate the pharmacokinetics of mitiglinide calcium tablets in healthy volunteers. Methods 30 healthy volunteers ...
Objective To establish a sensitive and specific LC-MS/MS method for the determination of mitiglinide calcium in human plasma, and investigate the pharmacokinetics of mitiglinide calcium tablets in healthy volunteers. Methods 30 healthy volunteers ...
2014, 32(1): 49-50,64.
doi: 10.3969/j.issn.1006-0111.2014.01.012
Abstract:
Objective To compare the stability of ethacridine solution influenced by three factors:pH value, antioxidants and inert gas, to find out the most economical and effective production of ethacridine solution for the hospital with the consideration of ...
Objective To compare the stability of ethacridine solution influenced by three factors:pH value, antioxidants and inert gas, to find out the most economical and effective production of ethacridine solution for the hospital with the consideration of ...
2014, 32(1): 51-52.
doi: 10.3969/j.issn.1006-0111.2014.01.013
Abstract:
Objective To synthesize the antitumor activity of twenty-six peptide melittin. Methods The melittin was synthesized by stepwise solid-phase peptide synthesis (SPPS). During the synthesis of melittin, wang-resin was chosen as solid supporter and HOB...
Objective To synthesize the antitumor activity of twenty-six peptide melittin. Methods The melittin was synthesized by stepwise solid-phase peptide synthesis (SPPS). During the synthesis of melittin, wang-resin was chosen as solid supporter and HOB...
2014, 32(1): 53-55.
doi: 10.3969/j.issn.1006-0111.2014.01.014
Abstract:
Objective To investigate the chemical constituents of Phyllanthus urinaria. Methods Multi-chromatographic methods were employed for the isolation and purification of chemical constituents of Phyllanthus urinaria. The structures were identified on t...
Objective To investigate the chemical constituents of Phyllanthus urinaria. Methods Multi-chromatographic methods were employed for the isolation and purification of chemical constituents of Phyllanthus urinaria. The structures were identified on t...
2014, 32(1): 56-58,67.
doi: 10.3969/j.issn.1006-0111.2014.01.016
Abstract:
Objective To establish HPLC method for the content determination of insulin in thermosensitive slow-release rectal liquid suppository, evaluate release characteristics in vitro. Methods The separation was performed on a Welch ultimate column(4.6 mm...
Objective To establish HPLC method for the content determination of insulin in thermosensitive slow-release rectal liquid suppository, evaluate release characteristics in vitro. Methods The separation was performed on a Welch ultimate column(4.6 mm...
2014, 32(1): 59-60,77.
doi: 10.3969/j.issn.1006-0111.2014.01.016
Abstract:
Objective To explore the clinical effect and identify the optimal concentration of different concentration of ropivacaine in ropivacaine combined with butorphanol in epidural anesthesia for cesarean section. Methods 1 038 patients for cesarean sec...
Objective To explore the clinical effect and identify the optimal concentration of different concentration of ropivacaine in ropivacaine combined with butorphanol in epidural anesthesia for cesarean section. Methods 1 038 patients for cesarean sec...
2014, 32(1): 61-64.
doi: 10.3969/j.issn.1006-0111.2014.01.017
Abstract:
Objective To compare the clinical effect of moxifloxacin and levofloxacin on treatment of multi-drug resistant pulmonary tuberculosis(TB). Methods From Jan 2011 to Dec 2012, 108 patients who were proved to be multi-drug resistant to tuberculosis in...
Objective To compare the clinical effect of moxifloxacin and levofloxacin on treatment of multi-drug resistant pulmonary tuberculosis(TB). Methods From Jan 2011 to Dec 2012, 108 patients who were proved to be multi-drug resistant to tuberculosis in...
2014, 32(1): 65-67.
doi: 10.3969/j.issn.1006-0111.2014.01.018
Abstract:
Objective To study the clinical effect of mifepristone combined with misoprostol and misoprostol in missed abortion curettage. Methods Seventy cases from April 2010 to August 2011 of medical termination of pregnancy in Huzhou family planning servi...
Objective To study the clinical effect of mifepristone combined with misoprostol and misoprostol in missed abortion curettage. Methods Seventy cases from April 2010 to August 2011 of medical termination of pregnancy in Huzhou family planning servi...
2014, 32(1): 68-70,73.
doi: 10.3969/j.issn.1006-0111.2014.01.019
Abstract:
Objective To investigate the utilization of clinical nutrition drugs in Hospital. Methods The utilization of EN and PN in Beijing Anzhen Union Hospital during 2009-2012 was analyzed statistically through hospital information system in respects of v...
Objective To investigate the utilization of clinical nutrition drugs in Hospital. Methods The utilization of EN and PN in Beijing Anzhen Union Hospital during 2009-2012 was analyzed statistically through hospital information system in respects of v...
2014, 32(1): 71-73.
doi: 10.3969/j.issn.1006-0111.2014.01.020
Abstract:
Objective To compare the differences in the drug utilization for infection prevention in combat injuries between the PLA and USA armed force. Methods The guidelines for the prevention of infections associated with combat-related injuries and tacti...
Objective To compare the differences in the drug utilization for infection prevention in combat injuries between the PLA and USA armed force. Methods The guidelines for the prevention of infections associated with combat-related injuries and tacti...
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