丹参素及其衍生物心血管作用机制的研究进展

焦育强; 刘文斌; 袁夏; 姜玉; 田霖; 金磊; 张川

doi:10.3969/j.issn.1006-0111.2015.05.002

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丹参素及其衍生物心血管作用机制的研究进展

焦育强, 刘文斌, 袁夏, 姜玉, 田霖, 金磊, 张川

文章导航 > 药学实践与服务 > 2015 > 33(5): 389-391,405

焦育强, 刘文斌, 袁夏, 姜玉, 田霖, 金磊, 张川. 丹参素及其衍生物心血管作用机制的研究进展[J]. 药学实践与服务, 2015, 33(5): 389-391,405. doi: 10.3969/j.issn.1006-0111.2015.05.002

引用本文:

JIAO Yuqiang, LIU Wenbin, YUAN Xia, JIANG Yu, TIAN Lin, JIN Lei, ZHANG Chuan. Study progress of Danshensu and its derivatives in cardiovascular mechanism[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(5): 389-391,405. doi: 10.3969/j.issn.1006-0111.2015.05.002

Citation:

JIAO Yuqiang, LIU Wenbin, YUAN Xia, JIANG Yu, TIAN Lin, JIN Lei, ZHANG Chuan. Study progress of Danshensu and its derivatives in cardiovascular mechanism[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(5): 389-391,405. doi: 10.3969/j.issn.1006-0111.2015.05.002

丹参素及其衍生物心血管作用机制的研究进展

doi: 10.3969/j.issn.1006-0111.2015.05.002

焦育强¹,
刘文斌²,
袁夏²,
姜玉²,
田霖¹,
金磊²,
张川^2,

1.
福建中医药大学药学院, 福建福州 350108
2.
第二军医大学药学院, 上海 200433

Study progress of Danshensu and its derivatives in cardiovascular mechanism

1.
School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China
2.
School of Pharmacy, Second Military Medical University, Shanghai 200433, China

摘要: 丹参素是丹参的主要水溶性活性成分之一,具有多种药理活性,尤其对心血管系统具有明显的保护作用。笔者从抗凋亡、抗氧化、抑制钙超载和作用于炎症反应通路等方面,对丹参素及其衍生物心血管药理作用机制进行综述。
- 丹参素 /
- 丹参素衍生物 /
- 抗凋亡 /
- 抗氧化 /
- 钙超载 /
- 炎症反应
Abstract: Danshensu is one of the main water soluble active ingredients of Salvia miltiorrhiza, which has many pharmacological activities, especially in cardiovascular system. The cardiovascular pharmacological mechanism of Danshensu and its derivatives from the view of anti-apoptosis, antioxidant, inhibiting calcium overload and role in the inflammatory reaction pathways etc. were summarized in this article.
- Danshensu /
- derivatives /
- anti-apoptosis /
- antioxidant /
- calcium overload /
- inflammatory reaction

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