Combination effect of traditional Chinese medicine penetration enhancers with titanoreine suppositories on treatment of external dissection for thrombotic external hemorrhoids
-
摘要: 目的 临床观察中药透皮吸收促进剂联合复方角菜酸酯栓治疗血栓外痔术后术区疼痛、岀血、水肿的疗效。 方法 选择本院普外科病房的痔病患者,分为3组:治疗组采用中药透皮促进剂联合外用复方角菜酸酯栓治疗;对照组(1)采用热水熏洗联合外用复方角菜酸酯栓治疗,对照组(2)仅外用复方角菜酸酯栓进行治疗。3组均用药1周。 结果 通过对2009年6月~2011年2月135例普外科病房病人入选研究发现,在术后第4天,治疗组的出血、疼痛改善明显好于对照组(1)和对照组(2),差异有统计学意义(P<0.05)。 结论 中药透皮促进剂联合复方角菜酸酯栓治疗血栓外痔术后止血、止痛方面具有更好的疗效。Abstract: Objective To detect the effect of traditional Chinese medicine penetration enhancers with titanoreine suppositories on the treatment of external dissection for thrombotic external hemorrhoids. Methods 90 outpatients were randomly divided into the treatment group (n=45) and the control group (n=45). The treatment groups were treated by traditional Chinese medicine penetration enhancers with titanoreine suppositories, on the while, the control group's were only treated by titanoreine suppositories. After a course of treatment, the general efficacy, reducing blood-stasis and swelling and alleviating anal pain were observed. Statistical analysis was conducted. Results The blooding and pain indicator of the treatment group were significantly lower than the control group in the 4th day after external dissection. (P<0.05). Conclusion Treatment of Chinese medicine penetration enhancers combined with titanoreine suppositories hada better efficacy.
-
[1] 吴阶平, 裘法祖,黄家驷.外科学[M].第六版.北京:人民卫生出版社,2000,1182. [2] 周映林. 血栓外痔剥离术后外科护理的疗效比较[J].中国医药指南,2010, 8(35):142. [3] 刘 淼. 痔切术后联合应用白敬宇痔疮膏及太宁栓40例分析[J].现代中西医结合杂志,2011,20(28):3580. [4] 徐 敏. 中药透皮吸收制剂的研究概况[J]. 中国中医药科技, 2008, 15(2):159. [5] 马 卓,沈 雄,陈前锋,等. 中药透皮吸收制剂的研究进展[J].中药材,2005, 28(12):1136. [6] 国家中医药管理局. 中医病证诊断疗效标准[M].南京:南京大学出版社,1994:131. [7] 国家中医药管理局. 中华人民共和国中医药行业标准·中医肛肠科病证诊断疗效标准[M].南京:南京大学出版社, 1995,1. [8] Walter RB. Pharmaceutic skin penetration enhancement[M]. New York:Marcel Dekker Inc, 1993:113. [9] Kunta JR,Goskonda VR,Brotherton HO,et al.Effect of menthol and related terpenes on the percutaneous absorption of propranolol across ex-cised hairless mouse skin[J].J Pharm Sci,1997,86(12):1369. [10] 朱健平, 王宗锐, 吴宋夏, 等. 龙脑促进药物经皮渗透作用研究[J].中国药学杂志,1999,34(2):104. [11] 难波恒雄.生药浴刺的研究(1):生药提取物的透皮吸收及透皮促进作用[J].国外医学:中医中药分册,1993,15(10):41. [12] 杨新庆. 复方角菜酸酯治疗痔全国多中心临床疗效分析[J].中国实用外科杂志,2002,22(11):685.
计量
- 文章访问数: 2568
- HTML全文浏览量: 301
- PDF下载量: 270
- 被引次数: 0