2025 Vol. 43, No. 1
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2025, 43(1): 1-5, 16.
doi: 10.12206/j.issn.2097-2024.202404005
Abstract:
Objective To investigate the effect and mechanism of miglitol on regulating the energy metabolism of brown adipocytes by activating UCP1 and preventing cold injury in mice after cold exposure. Methods Primary brown adipocytes were induced into...
2025, 43(1): 6-9, 21.
doi: 10.12206/j.issn.2097-2024.202404006
Abstract:
Objective To establish an HPLC method to determine the concentration of inositol nicotinate（IN） in rat skin, and study the pharmacokinetic characteristics of IN after transdermal administration of heparin sodium inositol nicotinate cream in rats. ...
2025, 43(1): 10-16.
doi: 10.12206/j.issn.2097-2024.202404008
Abstract:
Object To study the efficacy and potential mechanism of Tongbianling capsule in constipation. Methods The effects of Tongbianling capsule on intestinal motility in normal mice and carbon powder propulsion rate in small intestine of constipat...
2025, 43(1): 17-21.
doi: 10.12206/j.issn.2097-2024.202404009
Abstract:
Objection To study and compare the pharmacodynamics in the treatment of chronic pharyngitis between Compound Heishen pills and Compound Heishen Drop pills. Methods Sixty healthy Wistar rats were randomly divided into blank group, positive con...
2025, 43(1): 22-25, 46.
doi: 10.12206/j.issn.2097-2024.202404030
Abstract:
Objective To establish an effective management mode, play the full role of DRGs in rational drug use, formulate the pharmaceutical clinical path, and intervene the prescription behavior of doctors, which could improve the level of rational drug us...
2025, 43(1): 26-29, 40.
doi: 10.12206/j.issn.2097-2024.202404034
Abstract:
Objective To analyze the adverse reaction reports （ADRs） of drug-induced liver injury in recent ten years, explore the characteristics and related rules of drug-induced liver injury, and provide reference for clinical safe drug use. Methods AD...
2025, 43(1): 30-40.
doi: 10.12206/j.issn.2097-2024.202409035
Abstract:
Objective To evaluate the efficacy of Puerariae lobatae radix （PLR） and Anemarrhenae Rhizoma （AR） in preventing and treating Alzheimer’s disease （AD） and explore its potential mechanism of action by LC-MS serum metabolomics strategy. Methods T...
2025, 43(1): 41-46.
doi: 10.12206/j.issn.2097-2024.202408031
Abstract:
Objective To explore the impact of national volume-based procurement policies on the use of medicines in treatment of benign prostatic hyperplasia （BPH） and provide data support for the rational clinical use of medicines in BPH treatment. Method...
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