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2024 Vol. 42, No. 7

Cover Catalogue
Display Method:
Research progress on quantitative detection methods of lateral flow immunochromatography assay
GU Jiayu, HU Xiner, WANG Xiaofei, ZHANG Ying, ZHANG Hai, CAO Yan
2024, 42(7): 273-277, 284. doi: 10.12206/j.issn.2097-2024.202307037
Abstract(6265) HTML (3164) PDF (1282KB)(98)
Abstract:
Lateral flow immunochromatography assay is a new instantaneous detection technology that employs a chromatographic membrane and labeling materials for detection. This detection technology is convenient, fast, and inexpensive, and is therefore widely ...
Progress on pharmaceutical characteristics of potassium-competitive acid blocker
WANG Yaozhen, XU Can, LV Shunli, TIAN Jing, ZHANG Dongwei
2024, 42(7): 278-284. doi: 10.12206/j.issn.2097-2024.202306040
Abstract(10910) HTML (3672) PDF (1004KB)(73)
Abstract:
As a new class of acid inhibitors, potassium-competitive acid blocker(P-CAB) inhibits the conformational transition of H+, K+-ATPase with subsequent suppression of H+, K+ exchanging by binding reversibly near the K+ binding site of H+, K+-ATPase, whi...
The roles of Bajitianwan formula on Aβ-injured osteoblasts and the mechanism based on network pharmacology
JIANG Tao, XU Weifan, JIANG Yiping, XIA Tianshuang, XIN Hailiang
2024, 42(7): 285-290, 296. doi: 10.12206/j.issn.2097-2024.202305011
Abstract(9540) HTML (1541) PDF (2487KB)(17)
Abstract:
Objective  To explore the effect of Bajitianwan(BJTW)formula on bone formation of Aβ-injured osteoblasts and its mechanism.   Methods  Osteoblasts isolated from neonatal 24-hour Wistar rats were used for the study, and osteoblasts were subjected t...
Exploration of the role and mechanism of all-trans retinoic acid on activation and oxidative stress of hepatic stellate cell
XIU Jianping, YANG Chaoai, LIU Xi’ao, PAN Qianyu, WEI Guangxu, WANG Weixing
2024, 42(7): 291-296. doi: 10.12206/j.issn.2097-2024.202312054
Abstract(7968) HTML (1640) PDF (1501KB)(45)
Abstract:
Objective  To explore the role and potential mechanisms of all-trans retinoic acid (ATRA) on activation and oxidative stress of hepatic stellate cell (HSC).   Methods  Platelet-derived growth factor (PDGF-bb, 10 ng/ml) was applied to induce the ac...
HPLC fingerprint of Radix Rhubarb and forbidden pesticide residues
MAO Zeling, WEN Bo
2024, 42(7): 297-304, 314. doi: 10.12206/j.issn.2097-2024.202310057
Abstract(3778) HTML (1055) PDF (1662KB)(6)
Abstract:
Objective   To establish the HPLC fingerprint and pesticide residue detection methods for different kinds of rhubarb, and evaluate the quality of rhubarb comprehensively.   Methods   20 batches of three types of rhubarb were collected and analyzed...
Effects of dulaglutide combined with metformin on body metabolism, body fat composition and serum adipokines in obese patients with type 2 diabetes mellitus
MAO Zhiyi, WANG Xiaoyan, CHEN Xiaoying, TANG Yifei
2024, 42(7): 305-309. doi: 10.12206/j.issn.2097-2024.202305032
Abstract(6205) HTML (1811) PDF (882KB)(13)
Abstract:
Objective  To explore the clinical efficacy of dulaglutide combined with metformin in the treatment of obese patients with type 2 diabetes mellitus(T2DM).   Methods  A total of 200 obese patients with T2DM who were treated in Shanghai Jiading Dist...
Some thoughts on compulsory licensing of pharmaceutical patents in emergency situations
FEI Yonghe, CUI Lijun, CHEN Jing
2024, 42(7): 310-314. doi: 10.12206/j.issn.2097-2024.202309047
Abstract(3240) HTML (1820) PDF (926KB)(12)
Abstract:
Objective  To explore the conditions for compulsory licensing of pharmaceutical patents and the steps for implementing compulsory licensing of pharmaceutical patents.   Methods   The current situation and problem of compulsory licensing of pharmac...
Analysis of drug procurement model of multiple areas based on joint inventory in public hospitals
QU Wenjun, BAI Ruonan, CUI Li, ZHOU Yan
2024, 42(7): 315-318. doi: 10.12206/j.issn.2097-2024.202401002
Abstract(4176) HTML (2011) PDF (853KB)(25)
Abstract:
Objective  To evaluate the application effect of joint inventory management method in drug procurement and control management in multiple hospital areas.   Methods  Based on the joint inventory management model, four pilot drugs were selected from...