2024 Vol. 42, No. 3
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2024, 42(3): 89-93, 120.
doi: 10.12206/j.issn.2097-2024.202303012
Abstract:
The domestic and international research progress on the regulation of gut microbiota by Traditional Chinese Medicine (TCM) ingredients and their impact on intestinal absorption and transportation were summarized, which provided assistance for subsequ...
The domestic and international research progress on the regulation of gut microbiota by Traditional Chinese Medicine (TCM) ingredients and their impact on intestinal absorption and transportation were summarized, which provided assistance for subsequ...
2024, 42(3): 94-100.
doi: 10.12206/j.issn.2097-2024.202306013
Abstract:
Heart failure is the terminal stage of various cardiovascular diseases and a leading cause of death. For a long time, natural medicines have been used to treat heart failure（HF） with remarkable effects. In this paper, the Traditional Chinese Medicine...
Heart failure is the terminal stage of various cardiovascular diseases and a leading cause of death. For a long time, natural medicines have been used to treat heart failure（HF） with remarkable effects. In this paper, the Traditional Chinese Medicine...
2024, 42(3): 101-107.
doi: 10.12206/j.issn.2097-2024.202206051
Abstract:
Objective To prepare silymarin phospholipids complex（SM-PC） and investigate its physicochemical properties. Methods On the basis of single-factor tests, the drug-lipid ratio, drug concentration and reaction temperature were selected as the fac...
2024, 42(3): 108-113.
doi: 10.12206/j.issn.2097-2024.202305038
Abstract:
Objective To prepare flumazenil sublingual tablets and study its bioavailability. Methods Flumazenil sublingual tablets were prepared by compressing flumazenil inclusion compound with hydroxypropyl-β-cyclodextrin as the inclusion material. In ...
2024, 42(3): 114-120.
doi: 10.12206/j.issn.2097-2024.202309057
Abstract:
Objective Alpha-1-acid glycoprotein （ORM） was a new target for the development of weight loss drugs. To search for potential weight loss drugs that could target ORM from the compound library of already marketed drugs based on drug repurposing. M...
2024, 42(3): 121-126.
doi: 10.12206/j.issn.2097-2024.202209018
Abstract:
Objective To study the effect and mechanism of the thapsigargin combined with gefitinib on the proliferation of human lung adenocarcinoma gefitinib resistance cell line PC9/GR. Methods The cell viability of PC9/GR treated with gefitinib alone ...
2024, 42(3): 127-130.
doi: 10.12206/j.issn.2097-2024.202306043
Abstract:
Objective To establish a method for the simultaneous determination of DOX·HCl and LND. Methods HPLC was performed on Agilent 5 HC-C18（2） （4.6 mm × 250 mm, 5 µm） column. The mobile phase was methanol-0.1% TFA aqueous solution, and the gradient ...
2024, 42(3): 131-134.
doi: 10.12206/j.issn.2097-2024.202210060
Abstract:
Objective To analyze the postoperative therapeutic effect of prokinetic agents in patients after tricuspid valve replacement （TVR） under cardiopulmonary bypass. Methods Patients received TVR under cardiopulmonary bypass （during June 2010 to De...
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