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2023 Vol. 41, No. 2

Cover Catalogue
Display Method:
Application of cellular metabolomics in central nervous system diseases
HE Xiaoli, SHI Yiwei, WANG Hui, DAI Jianying, HONG Zhanying
2023, 41(2): 63-69. doi: 10.12206/j.issn.2097-2024.202203006
Abstract(10465) HTML (3839) PDF (1317KB)(69)
Abstract:
Cell metabolomics is an important branch of metabolomics, which could dynamically monitor cell response and metabolic changes after drugs acting on cells, and look for potential biomarkers. Cell metabolomics has been widely used in illustration of di...
Research progress of anti-sepsis treatment using traditional Chinese medicine
LING Zhongyi, CHEN Linlin, XING Xinhao, WANG Yan
2023, 41(2): 70-73. doi: 10.12206/j.issn.2097-2024.202204063
Abstract(6661) HTML (4664) PDF (904KB)(40)
Abstract:
Sepsis is life-threatening with complex pathogenesis. It is a big problem in the medical field. Clinically, antibiotics, hormones and mechanical ventilation are the main treatments. There is a lack of specific therapeutic drugs. The treatment effect ...
Effect of the insulated environment on brain function and its therapeutical drugs
SONG Xingshuang, LI Qi, DU Lina
2023, 41(2): 74-80. doi: 10.12206/j.issn.2097-2024.202208042
Abstract(5297) HTML (1560) PDF (1250KB)(28)
Abstract:
The long-term insulated environment (such as burial after earthquakes, trapped elevators, etc.) can affect emotion by affecting neural plasticity and neurotransmitters, while the bad emotions can further affect normal cognition. Drugs can intervene t...
Advances in mosquito repellents
CHEN Xinlu, TAI Zongguang, ZHU Quangang, GAO Shen
2023, 41(2): 81-85, 90. doi: 10.12206/j.issn.2097-2024.202103036
Abstract(20976) HTML (4951) PDF (1280KB)(248)
Abstract:
Mosquitoes are the biological vectors of many diseases. Mosquito-borne infectious diseases are serious public health problems in tropical areas. With the increasing resistance of mosquitoes to insecticides, it becomes difficult to control mosquito-bo...
Design, synthesis and antifungal activity of novel triazoles containing propyl side chains
ZHANG Haidong, YUAN Fumiao, ZHANG Dazhi, JIANG Yuanying, YU Shichong
2023, 41(2): 86-90. doi: 10.12206/j.issn.2097-2024.202208016
Abstract(4503) HTML (1664) PDF (1045KB)(16)
Abstract:
Objective  To study the antifungal activity of a new series of triazole compounds with n-propyl side chain and disubstituted benzyl structure.   Methods  Eleven target compounds were designed and synthesized. The structures were confirmed by 1H NM...
Study on material basis of cathepsin K targeted inhibitor in Erzhi Wan
JIANG Yiping, JIN Yue, ZHANG Zhiwei, XIA Tianshuang, XU Jiale, XUE Liming
2023, 41(2): 91-96, 118. doi: 10.12206/j.issn.2097-2024.202202008
Abstract(3702) HTML (1367) PDF (1505KB)(17)
Abstract:
Objective  To investigate the active ingredients and components that inhibiting cathepsin K activity in Erzhi Wan, a classic kidney-tonifying formula.   Methods  Then-butanol, dichloromethane, ethyl acetate and petroleum ether parts and 30 active ...
Cordyceps sinensis extract protects against the ovariectomy-induced bone loss via the action on osteoclasts
PENG Weibiao, WANG Ting, FENG Xu, WANG Jiachun, ZHANG Zhenzhen, CHU Zhiyong
2023, 41(2): 97-105. doi: 10.12206/j.issn.2097-2024.202105037
Abstract(4837) HTML (3006) PDF (8774KB)(49)
Abstract:
Objective  To explore the effects of Cordyceps sinensis extract (CSE) on osteoporosis and RANKL-mediated osteoclastogenesis.   Methods  Bone marrow-derived macrophages (BMMs) was isolated from the bone marrow of C57BL/6 mice. CSE was added in oste...
Research on quality control standard and safety of liquid bandage
XU Hang, WANG Tianyu, ZHANG Lingna, SONG Hongtao
2023, 41(2): 106-112, 129. doi: 10.12206/j.issn.2097-2024.202103063
Abstract(7343) HTML (2608) PDF (1419KB)(43)
Abstract:
Objective   To investigate the quality and safety of liquid bandage and establish a reliable quality control method.   Methods  The quality of liquid bandage was evaluated by appearance, film forming time, viscosity, comfort, waterproof and air pe...
Study on quality standard of Gardenia jasminoides and its effective parts
GE Wen, GAO Congcong, LI Dongyang, CHEN Weidong, ZHOU Tingting
2023, 41(2): 113-118. doi: 10.12206/j.issn.2097-2024.202210003
Abstract(4724) HTML (1920) PDF (1180KB)(22)
Abstract:
Objective   To study the quality standard of Gardenia jasminoides and its effective parts.   Methods  TLC was used to identify Gardenia jasminoides and its effective parts. The heavy metals, harmful elements, and moisture in Gardenia jasminoides a...
Optimization of microwave-assisted extraction of green tea polyphenols by response surface methodology
MA Xiaoyu, LUO Caiping, LIU Yue
2023, 41(2): 119-124, 134. doi: 10.12206/j.issn.2097-2024.202205009
Abstract(4859) HTML (2760) PDF (3496KB)(25)
Abstract:
Objective   To optimize the microwave-assisted extraction process of green tea polyphenols.   Methods   The extraction yield of tea polyphenols was figured up by building the standard curve of gallic acid and examining the concentration of tea pol...
Analgesia effect of dexamethasone combined with dexmedetomidine on femoral nerve block with ropivacaine after total knee replacement in elderly patients
DONG Fahui, HAN Jingang
2023, 41(2): 125-129. doi: 10.12206/j.issn.2097-2024.202109020
Abstract(3091) HTML (1712) PDF (974KB)(30)
Abstract:
Objective  To observe the analgesia effect of dexamethasone combined with dexmedetomidine on femoral nerve block with ropivacaine after total knee replacement in elderly patients.   Methods  96 elderly patients undergoing total knee replacement wi...
Current status and suggestions of home pharmacy services under the background of aging
SUN Mengyao, DENG Min, ZHOU Quan, WANG Zhuo
2023, 41(2): 130-134. doi: 10.12206/j.issn.2097-2024.202208099
Abstract(5193) HTML (2043) PDF (994KB)(43)
Abstract:
Objective  To explore how to further improve the quality of home pharmacy services under the background of aging.   Methods  The development history of home pharmacy service in our country in recent years was summarized, and the current status and...