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2020 Vol. 38, No. 2

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Recommendations for prevention and treatment of device-related pressure injuries during COVID-19 period
ZHANG Yunchang, SHENG Chunquan, WANG Bingkai, MA Zhiqiang, YANG Feng
2020, 38(2): 97-100, 109. doi: 10.3969/j.issn.1006-0111.202003018
Abstract(5382) HTML (2805) PDF (518KB)(47) Cited By (1)
Abstract:
With the outbreak of COVID-19, non-stop working medical staff need to wear protective equipment for a long time, which could easily cause device-related pressure injuries to nose, cheek, forehead or the back of auricle, and might even cause facial sk...
Traditional Chinese medicine in the treatment and rehabilitation for Coronavirus Disease 2019
YOU Benming, WANG Zhongzhuang
2020, 38(2): 101-104. doi: 10.3969/j.issn.1006-0111.202003061
Abstract(5680) HTML (2258) PDF (452KB)(44) Cited By (13)
Abstract:
Based on national health insurance policy, traditional Chinese medicine (TCM) clinical practice and newly revealed pathological changes in Coronavirus Disease 2019 (COVID-19), the early TCM utilization was recommended to promote blood circulation and...
Advances in research on the impact of the plateau environmental on the drug metabolism
GAO Zizhao, WANG Rong, ZHAO Anpeng
2020, 38(2): 105-109. doi: 10.3969/j.issn.1006-0111.201912096
Abstract(4787) HTML (2524) PDF (518KB)(26) Cited By (6)
Abstract:
Plateau environment will affect the metabolism of drugs in the body, which will cause changes in pharmacokinetic parameters, expression and function of drug metabolizing enzymes and transporters. With the rapid development of the pharmaceutical indus...
Research on chemical components and biological activities of the iridoids in Morinda genus
SHEN Yi, ZHANG Qi, LIU Mengqin, HE Yuqiong, XIN Hailiang, QIN Luping, ZHANG Qiaoyan
2020, 38(2): 110-114, 119. doi: 10.3969/j.issn.1006-0111.201907143
Abstract(6288) HTML (3152) PDF (501KB)(25) Cited By (9)
Abstract:
Morinda genus of Rubiaceae has been widely used in medicine at home and abroad. Many parts of Morinda tree are utilized in research, mainly including roots, stems, leaves, branches and seeds. Through the research of online databases, the chemical com...
Establishment of mouse myocardial infarction model and early electrocardio- gram assessment
HU Wenjun, WANG Pin, ZHENG Sili, WANG Dongsheng, MIAO Chaoyu
2020, 38(2): 115-119. doi: 10.3969/j.issn.1006-0111.202001011
Abstract(8010) HTML (6637) PDF (643KB)(101) Cited By (6)
Abstract:
Objective  To establish and optimize a mouse myocardial infarction (MI) model, and to use twice limb lead ECGs immediately after coronary ligation and 4 h after surgery to evaluate the occurrence of myocardial infarction.  Methods  Twenty-nine mal...
Microdialysis recovery of cefradine in vitro
YANG Xianmi, XU Xiaojian, WANG Xuebin, WANG Zhuo, Wang Tongsheng
2020, 38(2): 120-123, 128. doi: 10.3969/j.issn.1006-0111.201910044
Abstract(5306) HTML (2623) PDF (783KB)(21) Cited By (2)
Abstract:
Objective  To determine the in vitro recovery rate and influencing factors of cefradine microdialysis.  Methods  Two different methods (loss method, gain method) of microdialysis concentration and LC-MS/MS were used to determine the in vitro recov...
Determination of the content of Gd3+ in gadoteric acid meglumine salt injection by ICP-MS method
WANG Qirong, CHEN Jieyi, SUN Miao, CHEN Yuping, YANG Feng
2020, 38(2): 124-128. doi: 10.3969/j.issn.1006-0111.201908132
Abstract(4112) HTML (1883) PDF (578KB)(33) Cited By (2)
Abstract:
Objective  To establish a method for determining the content of Gd3+ in gadoteric acid meglumine salt injection.  Methods  ICP-MS was used. The separation column was a metal chelate column (1-ml Chelating Sepharose column), column temperature was ...
The effects of medical sodium hyaluronate gel on the tumor proliferation and metastasis
CAI Tongkai, YANG Wensheng, CAO Yongbing, HAN Hua, YAN Lan
2020, 38(2): 129-134. doi: 10.3969/j.issn.1006-0111.201911108
Abstract(5485) HTML (2835) PDF (923KB)(19) Cited By (3)
Abstract:
Objective  To investigate the effect of medical sodium hyaluronate gel (HA) on the growth and metastasis of abdominal and pelvic tumor cells in vitro and in nude mice.  Methods  Three tumor cells, Hela, CT26 and HCT116, were used to investigate th...
Effects of hawthorn and melanoidins on the in-vitro growth of Bifidobacterium and E.coli
WANG Yun, LU Min, LIANG Jie, SUN Hua, ZHANG Mengqi, LAN Zelun, WAN Jun, ZHOU Xia
2020, 38(2): 135-137, 165. doi: 10.3969/j.issn.1006-0111.201904129
Abstract(4649) HTML (1897) PDF (594KB)(18) Cited By (14)
Abstract:
Objective  Effect of hawthorn and melanoidins on the in-vitro growth of Bifidobacterium and E.coli.  Methods  According to methods of the Chinese pharmacopoeia (2015),the charred hawthorn was prepared. The melanoidins in charred hawthorn were sepa...
Identification of chemical constituents of Xiakucao Xiaoliu mixture by HPLC-TOF/MS
DAI Yuanyuan, WANG Xiaohe, MA Minghua, JI Qiangguo, GU Xiaoyan, WU Tiejun, NIAN Hua
2020, 38(2): 138-142, 155. doi: 10.3969/j.issn.1006-0111.201907116
Abstract(4526) HTML (1892) PDF (659KB)(20) Cited By (7)
Abstract:
Objective  To identify the chemical constituents of Xiakucao Xiaoliu mixture by high performance liquid chromatography-high resolution time-of-flight mass spectrometry (HPLC-TOF/MS).  Methods  The chromatographic separation ACE (3.0mm×150 mm) colu...
Quality control and evaluation of Shengmai injection based on anti-oxidant and anti-inflammatory biological effects
YU Yue, LU Juan, CHAI Ruiping, LYU Xinkai, DENG Minghui, CHEN Xi
2020, 38(2): 143-147. doi: 10.3969/j.issn.1006-0111.201906029
Abstract(5548) HTML (2468) PDF (649KB)(18) Cited By (9)
Abstract:
Objective  To establish a quality evaluation method for Shengmai injection with antioxidant and anti-inflammatory effects as indicators.  Methods  Using water-soluble vitamin E (Trolox) and N-nitro-L-arginine methyl ester (L-NAME) as control drugs...
Cisatracurium assay in human plasma by LC-MS
XIN Bo, WAN Lili, WANG Jing, LIU Jinbian, HUO Yan, GUO Cheng
2020, 38(2): 148-151. doi: 10.3969/j.issn.1006-0111.201909001
Abstract(4823) HTML (1740) PDF (1490KB)(39) Cited By (1)
Abstract:
Objective  To establish a LC-MS method of cisatracurium assay in human plasma for clinical therapeutic drug monitoring.  Method  Propafenone Hydrochloride was used as the internal standard. The plasma samples were treated with 2% formic acid aqueo...
Comparative study on volatile oil in Rhizoma chuanxiong by steam distillation and supercritical fluid extraction
DENG Peng, WEI Feixue, WEN Yi, WANG Baoyi, CHEN Shan
2020, 38(2): 152-155. doi: 10.3969/j.issn.1006-0111.201907022
Abstract(4190) HTML (3414) PDF (651KB)(37) Cited By (12)
Abstract:
Objective  To clarify the influence of the extraction process on its active ingredients by comparing the volatile oils of Rhizoma Chuanxiong obtained under different processes.  Methods  The volatile oil of Rhizoma Chuanxiong was extracted by supe...
Study on the relationship between soil and quality of Astragalus membranaceus in Minle, Gansu
ZHANG Bo, BAN Xiaojun, YU Zheyuan, LI Xiaofang, WANG Xiaoxia
2020, 38(2): 156-160. doi: 10.3969/j.issn.1006-0111.201906077
Abstract(4356) HTML (2066) PDF (425KB)(18) Cited By (4)
Abstract:
Objective  To study the relationship between the quality of Astragalus membranaceus and soil in Gansu Minle.  Methods  we sampled the medicinal materials and soils of Astragalus membranaceus in Minle County, and determined the medicinal quality, s...
Determination of total polysaccharide content and analysis of monosaccharide components in the caulis polygoni multiflori mixture
YE Caifa, CAI Yuehui, ZENG Qiping, CAO Yixiang, CHEN Jinshan
2020, 38(2): 161-165. doi: 10.3969/j.issn.1006-0111.201908021
Abstract(4739) HTML (2484) PDF (630KB)(31) Cited By (6)
Abstract:
Objective  To establish a method for analyzing total polysaccharide content and its monosaccharide composition in the caulis polygoni multiflori mixture.  Methods  The polysaccharides of the caulis polygoni multiflori mixture were extracted by wat...
Simultaneously detect three illegal additive components in Yinhuang soft capsule by TLC-SERS
SONG Weiguo, LU Yonghui, ZHANG Zhonghu, ZHANG Huimin
2020, 38(2): 166-169. doi: 10.3969/j.issn.1006-0111.201908092
Abstract(5562) HTML (1724) PDF (683KB)(22) Cited By (4)
Abstract:
Objective  To establish a simultaneous detection of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added in Yinhuang soft capsules by TLC-SERS.  Methods  The samples to be measured were placed on the silica gel plate, and the th...
Clinical efficacy of TCM syndrome differentiation combined with entecavir in chronic hepatitis B patients
SHEN Qigang, HAN Zongru, MIN Xiaochun, YAO Qin, MA Weina
2020, 38(2): 170-173. doi: 10.3969/j.issn.1006-0111.201904148
Abstract(4565) HTML (2288) PDF (439KB)(16) Cited By (19)
Abstract:
Objective  To investigate the clinical effect of traditional Chinese medicine syndrome differentiation-based treatment combined with entecavir in the treatment of chronic hepatitis B.  Methods  A total of 80 outpatients with chronic hepatitis B we...
Analysis of adverse reactions in 312 cases of gemcitabine
YAO Nannan, LIN Lili, HUANG Shan, FU Wenqian, SONG Hongtao
2020, 38(2): 174-178. doi: 10.3969/j.issn.1006-0111.201905052
Abstract(5370) HTML (2997) PDF (463KB)(32) Cited By (9)
Abstract:
Objective  Based on the data of gemcitabine adverse reactions (ADR), the characteristics and patterns of ADR occurrence were analyzed. The guidance for the rational clinical use of gemcitabine was provided.  Methods  From our information system, t...
A retrospective analysis of the efficacy and safety of dicycloplatin in the treatment of malignant tumor
ZHANG Shuang, CHEN Mengli, YIN Hong, XU Fenghua
2020, 38(2): 179-183. doi: 10.3969/j.issn.1006-0111.201904096
Abstract(5977) HTML (3066) PDF (629KB)(32)
Abstract:
Objective  To observe the short-term efficacy and adverse reactions of dicycloplatin in the treatment of malignant tumors.  Methods  A retrospective analysis was performed in our hospital from January 2017 to August 2018 using dicycloplatin to tre...
Medical big data analysis of the clinical off-label use of proton pump inhibitors
MAO Xufeng, YANG Zhangwei
2020, 38(2): 184-188. doi: 10.3969/j.issn.1006-0111.201909086
Abstract(4174) HTML (2514) PDF (554KB)(59) Cited By (18)
Abstract:
Objective  To explore the main causes of the overuse of proton pump inhibitor (PPIs) in domestic hospitalized patients.  Methods  The electronic medical records of patients in 20 general hospitals from January 1, 2015 to March 31, 2018 were analyz...
Effects of comprehensive intervention on the application of special-use-grade antibacterial agents and on bacterial resistance in oncology department
WANG Tao, ZHOU Baozhu, YU Fang, ZHU Jie, WANG Ying
2020, 38(2): 189-192. doi: 10.3969/j.issn.1006-0111.201908070
Abstract(3845) HTML (2195) PDF (445KB)(26) Cited By (8)
Abstract:
Objective  To investigate the comprehensive intervention of special-use-grade antibacterial agents and their effects on bacterial resistance in oncology department, and analyze the effects of comprehensive intervention.  Methods  The medical recor...