2017 Vol. 35, No. 2
Display Method:
2017, 35(2): 97-101.
doi: 10.3969/j.issn.1006-0111.2017.02.001
Abstract:
Acute mountain sickness (AMS) is a self-limiting medical condition characterized by headache, nausea, fatigue, dizziness, and insomnia. AMS usually occurs after rapid ascent to high altitudes in non-altitude acclimatized individuals. Extensive studie...
Acute mountain sickness (AMS) is a self-limiting medical condition characterized by headache, nausea, fatigue, dizziness, and insomnia. AMS usually occurs after rapid ascent to high altitudes in non-altitude acclimatized individuals. Extensive studie...
2017, 35(2): 102-107,149.
doi: 10.3969/j.issn.1006-0111.2017.02.002
Abstract:
Nitidine is a benzophenanthridine alkaloid derived from Zanthorulum nitidum (Roxb.) DC root. Research shows that nitidine displays rich biological activities, such as anti-tumor, anti-inflammatory, anti-malaria and etc. This paper reviewed the progre...
Nitidine is a benzophenanthridine alkaloid derived from Zanthorulum nitidum (Roxb.) DC root. Research shows that nitidine displays rich biological activities, such as anti-tumor, anti-inflammatory, anti-malaria and etc. This paper reviewed the progre...
2017, 35(2): 108-111,140.
doi: 10.3969/j.issn.1006-0111.2017.02.003
Abstract:
In recent years, pharmacokinetics of traditional Chinese medicine has become essential for the modernization of traditional Chinese medicine. Pharmacokinetics is an important means for connecting traditional Chinese medicine with western medicine. Me...
In recent years, pharmacokinetics of traditional Chinese medicine has become essential for the modernization of traditional Chinese medicine. Pharmacokinetics is an important means for connecting traditional Chinese medicine with western medicine. Me...
2017, 35(2): 112-115,153.
doi: 10.3969/j.issn.1006-0111.2017.02.004
Abstract:
Rhizoma Corydalis, a herb with analgesic effects and being able to promote blood circulation, has been used for more than hundreds of years in China. Rhizoma Corydalis mainly comes from Zhejiang, Jiangsu, Hubei and Hunan province. The major effective...
Rhizoma Corydalis, a herb with analgesic effects and being able to promote blood circulation, has been used for more than hundreds of years in China. Rhizoma Corydalis mainly comes from Zhejiang, Jiangsu, Hubei and Hunan province. The major effective...
2017, 35(2): 116-120,125.
doi: 10.3969/j.issn.1006-0111.2017.02.005
Abstract:
Objective To study the protective effects of the total bakkenolides from P. tricholobus on high altitude hypoxia. Method Normobaric hypoxia model and acute hypobaric hypoxia model in mice, hypobaric hypoxia model in rats were established for this s...
Objective To study the protective effects of the total bakkenolides from P. tricholobus on high altitude hypoxia. Method Normobaric hypoxia model and acute hypobaric hypoxia model in mice, hypobaric hypoxia model in rats were established for this s...
2017, 35(2): 121-125.
doi: 10.3969/j.issn.1006-0111.2017.02.006
Abstract:
Objective To study the mechanisms of the drug resistance of DNA mismatch repair (MMR) deficient colorectal cancer (CRC) HCT-116 to 5-fluorouracil (5-Fu). Methods MLH1 deficiency HCT-116 cells were transfected with pcDNA3.1-MLH1 Vector.The expressio...
Objective To study the mechanisms of the drug resistance of DNA mismatch repair (MMR) deficient colorectal cancer (CRC) HCT-116 to 5-fluorouracil (5-Fu). Methods MLH1 deficiency HCT-116 cells were transfected with pcDNA3.1-MLH1 Vector.The expressio...
2017, 35(2): 126-129,192.
doi: 10.3969/j.issn.1006-0111.2017.02.007
Abstract:
Objective To prepare monoclonal antibodies (mAb) against mouse Metrnl and identify its specificity. Methods Mouse Metrnl polypeptide fragments and full-length protein were prepared as antigens to immunize mice.Then mice spleen cells were fused with...
Objective To prepare monoclonal antibodies (mAb) against mouse Metrnl and identify its specificity. Methods Mouse Metrnl polypeptide fragments and full-length protein were prepared as antigens to immunize mice.Then mice spleen cells were fused with...
2017, 35(2): 130-133.
doi: 10.3969/j.issn.1006-0111.2017.02.008
Abstract:
Objective To develop a HPLC method for determining 14 hydrolyzed amino acids in Pfaffia. Methods The sample was derivatized with phenyl isothiocyanate (PITC). Amino acids were separated on Waters XBridge Shield RP18 (4.6 mm×250 mm, 5 μm) column at ...
Objective To develop a HPLC method for determining 14 hydrolyzed amino acids in Pfaffia. Methods The sample was derivatized with phenyl isothiocyanate (PITC). Amino acids were separated on Waters XBridge Shield RP18 (4.6 mm×250 mm, 5 μm) column at ...
2017, 35(2): 134-137,173.
doi: 10.3969/j.issn.1006-0111.2017.02.009
Abstract:
Objective To establish methods for the determination of spinosin and total saponins in compound Zaoshen tablet. Methods The separation of spinosin was performed on Agilent Zorbax SB C18 column (250 mm×4.6 mm, 5 μm) at 30℃ with water and acetonitril...
Objective To establish methods for the determination of spinosin and total saponins in compound Zaoshen tablet. Methods The separation of spinosin was performed on Agilent Zorbax SB C18 column (250 mm×4.6 mm, 5 μm) at 30℃ with water and acetonitril...
2017, 35(2): 138-140.
doi: 10.3969/j.issn.1006-0111.2017.02.010
Abstract:
Objective Isolation, purification and structure identification of phthalides from Apium graveolens L. Methods Silica gel column and preparative TLC chromatography were used to isolate and purify the phthalide compounds. The structures of those comp...
Objective Isolation, purification and structure identification of phthalides from Apium graveolens L. Methods Silica gel column and preparative TLC chromatography were used to isolate and purify the phthalide compounds. The structures of those comp...
2017, 35(2): 141-145.
doi: 10.3969/j.issn.1006-0111.2017.02.011
Abstract:
Objective To synthesize a lipophilic prodrug of triptolide (TP) and improve its druggability. Methods Triptolide stearate (TP-SA) was synthesized via the DMAP-catalyzed DCC method and identified by MS, 1H-NMR and 13C-NMR. The shake-flask method was...
Objective To synthesize a lipophilic prodrug of triptolide (TP) and improve its druggability. Methods Triptolide stearate (TP-SA) was synthesized via the DMAP-catalyzed DCC method and identified by MS, 1H-NMR and 13C-NMR. The shake-flask method was...
2017, 35(2): 146-149.
doi: 10.3969/j.issn.1006-0111.2017.02.012
Abstract:
Objective To study the water extraction process of Zhuyu Zhitong gel paste. Methods With the yields of paeoniflorin and the dry paste as target, the water extraction process of Zhuyu Zhitong gel paste was optimized by an orthogonal experimental des...
Objective To study the water extraction process of Zhuyu Zhitong gel paste. Methods With the yields of paeoniflorin and the dry paste as target, the water extraction process of Zhuyu Zhitong gel paste was optimized by an orthogonal experimental des...
2017, 35(2): 150-153.
doi: 10.3969/j.issn.1006-0111.2017.02.013
Abstract:
Objective To determine telmisartan and amlodipine assay in the compound tablet. Methods First derivative UV spectrophotometry was used at wavelength 236 nm for telmisartan and 390 nm for amlodipine. Results Telmisartan content has a good linear re...
Objective To determine telmisartan and amlodipine assay in the compound tablet. Methods First derivative UV spectrophotometry was used at wavelength 236 nm for telmisartan and 390 nm for amlodipine. Results Telmisartan content has a good linear re...
2017, 35(2): 154-157,164,181.
doi: 10.3969/j.issn.1006-0111.2017.02.014
Abstract:
Objective To investigate drug brand preference and its effect on medication compliance and efficacy in patients with depression, to guide patient's rational use of limited medical resources and achieve a safe and effective drug use. Methods 459 out...
Objective To investigate drug brand preference and its effect on medication compliance and efficacy in patients with depression, to guide patient's rational use of limited medical resources and achieve a safe and effective drug use. Methods 459 out...
2017, 35(2): 158-160,181.
doi: 10.3969/j.issn.1006-0111.2017.02.015
Abstract:
Objective To evaluate the efficacy and side effects of combination therapy with aprepitant, tropisetron and dexamethasone in the prevention of nausea and vomiting induced by AC chemotherapy in patients after breast cancer surgery. Methods 72 breast...
Objective To evaluate the efficacy and side effects of combination therapy with aprepitant, tropisetron and dexamethasone in the prevention of nausea and vomiting induced by AC chemotherapy in patients after breast cancer surgery. Methods 72 breast...
2017, 35(2): 161-164.
doi: 10.3969/j.issn.1006-0111.2017.02.016
Abstract:
Objective To discuss antithrombotic drug treatment in subacute myocardial infarction patient with cerebral lacuna infarction and deep vein thrombosis. Methods Clinical pharmacists analyzed the causes of the blood clot formation, assessed ischemia a...
Objective To discuss antithrombotic drug treatment in subacute myocardial infarction patient with cerebral lacuna infarction and deep vein thrombosis. Methods Clinical pharmacists analyzed the causes of the blood clot formation, assessed ischemia a...
2017, 35(2): 165-166,170.
doi: 10.3969/j.issn.1006-0111.2017.02.017
Abstract:
Objective To study one male patient with cirrhosis for spironolactone induced gynecomastia and promote clinical pharmacists providing better pharmaceutical cares. Methods Based on the patient's diseases and medication history, clinical pharmacists ...
Objective To study one male patient with cirrhosis for spironolactone induced gynecomastia and promote clinical pharmacists providing better pharmaceutical cares. Methods Based on the patient's diseases and medication history, clinical pharmacists ...
2017, 35(2): 167-170.
doi: 10.3969/j.issn.1006-0111.2017.02.018
Abstract:
Objective To evaluate the utilization of human serum albumin (HSA) in intensive care unit (ICU) to promote rational use of HSA clinically. Methods Data were collected from the patients received HSA therapy during the period of January 1, 2015 to De...
Objective To evaluate the utilization of human serum albumin (HSA) in intensive care unit (ICU) to promote rational use of HSA clinically. Methods Data were collected from the patients received HSA therapy during the period of January 1, 2015 to De...
2017, 35(2): 171-173.
doi: 10.3969/j.issn.1006-0111.2017.02.019
Abstract:
Objective To explore the breakthrough point of pharmaceutical care for a patient with bronchiectasis, diabetes and gout. Methods The clinical pharmacist recommended appropriate antibiotics and gout medications. The dosage and therapy regimen were o...
Objective To explore the breakthrough point of pharmaceutical care for a patient with bronchiectasis, diabetes and gout. Methods The clinical pharmacist recommended appropriate antibiotics and gout medications. The dosage and therapy regimen were o...
2017, 35(2): 174-177.
doi: 10.3969/j.issn.1006-0111.2017.02.020
Abstract:
Objective To observe the immune effect of PD-1 (programmed death-1) antibody in the treatment of patients with advanced cancer. Methods From October 2015 to March 2016, 18 patients with advanced tumor were selected to receive the PD-1 antibody trea...
Objective To observe the immune effect of PD-1 (programmed death-1) antibody in the treatment of patients with advanced cancer. Methods From October 2015 to March 2016, 18 patients with advanced tumor were selected to receive the PD-1 antibody trea...
2017, 35(2): 178-181.
doi: 10.3969/j.issn.1006-0111.2017.02.021
Abstract:
Objective To explore the factors resulting in poor medication compliance in patients with cerebral infarction and study the effect of medication education by pharmacist on the compliance of patients. Methods 128 patients with cerebral infarction re...
Objective To explore the factors resulting in poor medication compliance in patients with cerebral infarction and study the effect of medication education by pharmacist on the compliance of patients. Methods 128 patients with cerebral infarction re...
2017, 35(2): 182-183,190.
doi: 10.3969/j.issn.1006-0111.2017.02.022
Abstract:
Objective To investigate the pharmaceutical care for the special population with asthma. Methods Clinical pharmacists participated in the process of drug treatment for the patient with acute asthma during pregnancy, and put forward appropriate medi...
Objective To investigate the pharmaceutical care for the special population with asthma. Methods Clinical pharmacists participated in the process of drug treatment for the patient with acute asthma during pregnancy, and put forward appropriate medi...
2017, 35(2): 184-186.
doi: 10.3969/j.issn.1006-0111.2017.02.023
Abstract:
Objective To introduce the teaching practice and experience of Pharmacy Administration in new era using a variety of teaching methods. Methods To review the characteristics and difficulties in teaching Pharmacy Administration, as well as some pract...
Objective To introduce the teaching practice and experience of Pharmacy Administration in new era using a variety of teaching methods. Methods To review the characteristics and difficulties in teaching Pharmacy Administration, as well as some pract...
2017, 35(2): 187-190.
doi: 10.3969/j.issn.1006-0111.2017.02.024
Abstract:
Objective To explore the role of clinical pharmacists in pharmaceutical care and medication errors prevention in geriatric inpatients. Methods 702 geriatric inpatients hospitalized from May 2015 to April 2016 were enrolled in this study. The patien...
Objective To explore the role of clinical pharmacists in pharmaceutical care and medication errors prevention in geriatric inpatients. Methods 702 geriatric inpatients hospitalized from May 2015 to April 2016 were enrolled in this study. The patien...
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