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2015 Vol. 33, No. 3

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New technologies for high throughput screening of effective traditional Chinese medicine components
DING Xuan, HONG Zhanying, CHAI Yifeng
2015, 33(3): 193-197. doi: 10.3969/j.issn.1006-0111.2015.03.001
Abstract(7488) PDF (3013KB)(1194)
Abstract:
The research progress on new technologies for high throughput screening of effective traditional Chinese medicine (TCM) components was summarized based on the recent documents at home and abroad, among which bio-chromatography, chip-technology and co...
Research progress on chemical constituents and pharmacological activities of Rosa chinensis
LIU Mouzhi, SONG Xia, JIANG Yuanying, CAO Yongbing, YAN Tianhua
2015, 33(3): 198-200,249. doi: 10.3969/j.issn.1006-0111.2015.03.002
Abstract(5576) PDF (813KB)(742)
Abstract:
The chemical constituents of Rosa chinensis Jacq were diverse, mainly including flavonoids, flavonoid glycosides, phenolic acids, aromatic oils, tannins and pigments. Its extract and some chemical constituents had shown multiple pharmacological activ...
Progress on active compositions and pharmacological effects of Celastrus orbiculatus
BIAN Jun
2015, 33(3): 201-204,220. doi: 10.3969/j.issn.1006-0111.2015.03.003
Abstract(4468) PDF (1415KB)(1121)
Abstract:
Celastrus orbiculatus Thunb. (Celastraceae) was widely distributed in China and more in the south area of the Yangtze River. Research showed the main chemical components including terpenoids, lipids, glycosides and flavonoids. Its pharmacological eff...
Research progress of novel drug gel
XIA Aixiao, SUN Yuan, MEN Xian
2015, 33(3): 205-208,216. doi: 10.3969/j.issn.1006-0111.2015.03.004
Abstract(3765) PDF (935KB)(969)
Abstract:
The novel drug gel was a new formulation, which was applied more and more in medicine field recently. The intelligent hydrogel, liposome gels, clathrate gels were summarized, which could be provide reference for counterparts.
Metabolic analysis of miconazole-treated Candida albicans by GC-MS
YANG Yua, WANG Hui, CAO Yingying, ZHU Zhenyu
2015, 33(3): 209-212. doi: 10.3969/j.issn.1006-0111.2015.03.005
Abstract:
Objective To investigate the metabolism in miconazole-treated Candida albicans, search for possible biomarkers and discuss the mechanism of miconazole. Methods GC-MS was employed to determine the metabolic fingerprint of Candida albicans before an...
Rapid identification of dye adulteration in Kadsura longipedunculata by paper-based SERS
ZHANG Guoqing, LI Dan, WANG Kebing
2015, 33(3): 213-216. doi: 10.3969/j.issn.1006-0111.2015.03.006
Abstract:
Objective To establish a paper-based surface-enhanced Raman scattering (SERS) method for the detection of dyed Kadsura longipedunculata Finet et Gagnep. Methods Supported silver nanoparticles on filter paper were synthesized simply by soaking meth...
The preparation of electret fluorouracil gel patch
WEI Pingyan, YUAN Wang, YANG Feng, CUI Lili
2015, 33(3): 217-220. doi: 10.3969/j.issn.1006-0111.2015.03.007
Abstract:
Objective To study and optimize the preparation process and abserve the related properties of electret fluorouracil gel patch. Methods the adhesives and moistening agents were screened by preliminary experiment. The optimal matrix proportion in th...
Effect of raw material purity on the degree of substitution of hydrophobically modified Bletilla striata polysaccharide
ZHAO Xuezhu, LIU Yang, WANG Yanping, LIU Fuqiang, ZHANG Qi, LIU Dan, ZHAO Nan, HAN Dan, ZHAO Qinglan
2015, 33(3): 221-225. doi: 10.3969/j.issn.1006-0111.2015.03.008
Abstract:
Objective To improve the degree of substitution of the cholesteryl by purifying cholesteryl succinyl ester(CHS), one of the raw materials. Methods CHS was purified by recrystallization, the pure CHS structure was characterizate by differential sca...
Comparative analysis of different states of polarized BV2 cells by GC-MS combined with metabonomic technology
WANG Yan, YU Zhongwang, CHEN Si, LI Ling, ZHU Zhenyu
2015, 33(3): 226-230. doi: 10.3969/j.issn.1006-0111.2015.03.009
Abstract(4647) PDF (1011KB)(1023)
Abstract:
Objective To analyze the different metabolites of the classical activated(M1), alternatively activated(M2) and resting BV2 cells by metabolomics method. Methods The mRNAs of several potential biomarkers were determined by real-time PCR analyses to...
Repeat-dose toxicity study of fibrin sealant in SD rats
DAI Xiaoyu, ZHU Hai, ZHANG Xiaodong, ZHANG Xiaofang, ZONG Ying, DAI Yimin, ZHANG Shuying, YUAN Bojun, LU Guocai
2015, 33(3): 231-234. doi: 10.3969/j.issn.1006-0111.2015.03.010
Abstract(4154) PDF (1160KB)(1010)
Abstract:
Objective To evaluate the safety of fibrin sealant (FS) intraperitoneal injection in SD rats. Methods 80 male and female SD rats were randomly divided into four groups (0, 85.5, 171.0, 342.0 mg/kg) by body weight. All rats were intraperitoneally i...
Screening for the hemostatic active extracts of Callicarpa nudiflora, in mice in vivo
YI Bo, ZHANG Min, LIN Hai, CHEN Tao, XU Wentong, FENG Shixiu
2015, 33(3): 235-237,241. doi: 10.3969/j.issn.1006-0111.2015.03.011
Abstract(3482) PDF (708KB)(661)
Abstract:
Objective To screen the hemostatic active extracts from Callicarpa nudiflora. Methods The powdered Callicarpa nudiflora was extracted with 70% EtOH and concentrated to give EtOH-extract. The EtOH-extract was further chromatographed over HP-20 macro...
The research of separation and purification technology for effective parts from Zhizichi decoction by macroporous absorption resina
HAN Yan, WEN Jun, ZHOU Tingting, FAN Guorong
2015, 33(3): 238-241. doi: 10.3969/j.issn.1006-0111.2015.03.012
Abstract:
Objective To optimize separation and purification technology of Zhizichi decoction by macroporous resina. Methods The content of total iridoid glycosides and total isoflavones were determined by ultraviolet spectrophotometry. Taking the content of...
Study on chemical constitunts of sponge Agelas mauritiana from the South China Sea
FANG Fengkai, TANG Hua, LIU Baoshu, ZHUANG Chunlin, SUN Peng, ZHANG Wen
2015, 33(3): 242-245,274. doi: 10.3969/j.issn.1006-0111.2015.03.013
Abstract:
Objective To investigate the chemical constituents of marine sponge Agelas mauritiana collected from the South China Sea. Methods The n-butanol extract of marine sponge Agelas mauritiana was separated and purified by repeated column chromatography...
Volatile components of different parts of Cryptotaenia japonica through GC-MS analysis and Kovats retention index
HU Siyi, BAO Qingqing, HAN Anbang, XIANG Zheng, LIN Chongliang
2015, 33(3): 246-249. doi: 10.3969/j.issn.1006-0111.2015.03.014
Abstract(4210) PDF (625KB)(908)
Abstract:
Objective To analyze and compare the chemical components of the volatile oil in different parts of Cryptotaenia japonica. Methods Essential oils were extracted from the root, stem, leaf, fruit of Cryptotaenia japonica through steam distillation. G...
Simultaneous determination of four ingredients in Gan Bawei capsule by HPLC-DAD
WU Lihong, CHU Zhongying, LIU Huijun
2015, 33(3): 250-252. doi: 10.3969/j.issn.1006-0111.2015.03.015
Abstract(3655) PDF (683KB)(837)
Abstract:
Objective To establish an HPLC-DAD method for simultaneous determination of four ingredients in Gan Bawei capsule. Methods HPLC method was adopted with C18 column(250 mm ×4.6 mm, 5 μm), Acetonitrile as mobile phase A and water as mobile phase B in...
Validation for sterility test method of nitroglycerin ointment
TAN Qiaoting, YAN Jia, ZHONG Guixiang, SONG Hongtao
2015, 33(3): 253-254. doi: 10.3969/j.issn.1006-0111.2015.03.016
Abstract(4279) PDF (364KB)(881)
Abstract:
Objective To establish and validate a method of sterility test for nitroglycerin ointment and validate this method. Methods Ten nitroglycerin ointments of 1 g were preheated oven to 45 ℃ for sample, and added to conical flask which containing melte...
Quality control method of peppermint water
CHEN Xu, LOU Yongming, HUANG Aiwen, SONG Hongtao
2015, 33(3): 255-257. doi: 10.3969/j.issn.1006-0111.2015.03.017
Abstract:
Objective To consummate a method of quality control of peppermint water. Methods Thin layer chromatography was used for the identification of peppermint oil.Gas chromatography was used for the determination of mentholum. Results The identificatio...
Changes of regulatory T cells in peripheral blood after gemcitabine chemotherapy for pancreatic cancer patients
KOU Xiaoxia, DING Yongmei, HUANG Yao, YUAN Zhengang, QIAN Qijun
2015, 33(3): 258-260,268. doi: 10.3969/j.issn.1006-0111.2015.03.018
Abstract:
Objective To investigate the influence of gemcitabine chemotherapy on levels of regulatory T cells(Tregs) in peripheral blood for patients with pancreatic cancer and provide evidence and reference for improving the efficacy of adoptive immunotherapy...
2015, 33(3): 261-262,288. doi: 10.3969/j.issn.1006-0111.2015.03.019
Abstract:
Lamotrigine for absence seizures in children and adolescents: a systematic review
TIAN Huaiping, GAO Huimin, ZHANG Jinlian, TANG Yuenian
2015, 33(3): 263-268. doi: 10.3969/j.issn.1006-0111.2015.03.020
Abstract:
Objective To assess the efficacy and safety of lamotrigine for absence seizures in children and adolescents. Methods Databases of PubMed, the Cochrane Library, EMbase, CENTRAL, VIP, WanFang, CBM and CNKI were electronically searched till August, 2...
Clinical efficacy of Shuxuetong injection in the treatment of 94 acute stage patients of chronic pulmonary heart disease
ZHENG Jia, WANG Shuquan
2015, 33(3): 269-271. doi: 10.3969/j.issn.1006-0111.2015.03.021
Abstract(2821) PDF (396KB)(386)
Abstract:
Objective To observe the effect of Shuxuetong injection in the improvement of heart and lung function on chronic pulmonary heart disease patients with basic treatment. Methods The control group was given low flow oxygen, sensitive antibiotics for ...
Observation of efficacy of Baidangba cream for hands and feet chap
CHANG Mingquan, WANG Yilin, CHEN Fang, WANG Gang
2015, 33(3): 272-274. doi: 10.3969/j.issn.1006-0111.2015.03.022
Abstract(3469) PDF (402KB)(495)
Abstract:
Objective To observe the curative effect of Baidangba cream for hands and feet chap. Methods 104 cases were divided into the treatment group and the control group containing typeⅠ, Ⅱ, Ⅲ according to chapped degree. The treatment group was treated b...
Impact of essential medicine system on rational drug use in Community Health Care Center of Chun'an District
WANG Jiefang, YU Zhiyong, YE Zuowu
2015, 33(3): 275-277,286. doi: 10.3969/j.issn.1006-0111.2015.03.023
Abstract(1270) PDF (783KB)(471)
Abstract:
Objective To study the impact of essential medicine system on rational drug use in Community Health Care Center of Chun'an District. Methods Essential drug system in Community Health Care Center of Chun'an District in Zhejiang Province was taken a...
Pharmacoeconomic evaluation of different dosing regimens of levofloxacin treating the bacterial infections of lower respiratory tract
FENG Shu
2015, 33(3): 278-282. doi: 10.3969/j.issn.1006-0111.2015.03.024
Abstract(3959) PDF (422KB)(353)
Abstract:
Objective To evaluate the pharmacoeconomics of two different dosing regimens of levofloxacin treating the bacterial infections of lower respiratory tract, and provide the basis for selecting the security, effective and economic treatment programs cl...
Application of Oracle and Java for the development of medicine information search software in Wangjing Hospital
ZONG Zhiyong, JIA Yingjue, LIU Xiaopeng, ZHANG Ruili, SU Shuang, LIU Quan
2015, 33(3): 283-286. doi: 10.3969/j.issn.1006-0111.2015.03.025
Abstract:
Objective Since it is a common problem for medical practice that paper instructions for medicine information are difficult to update and inconvenient to search, this article is to provide convenient service of pharmacy information for clinical pract...
2015, 33(3): 287-288. doi: 10.3969/j.issn.1006-0111.2015.03.026
Abstract(3211) PDF (389KB)(589)
Abstract: