2015 Vol. 33, No. 1
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2015, 33(1): 1-4,8.
doi: 10.3969/j.issn.1006-0111.2015.01.001
Abstract:
Mitochondria are the main places of cellular respiration as well as the citric acid cycle and oxidative phosphorylation.It plays an important role in controlling the life and death of cells.Mitochondrial dysfunction leads to a series of human disease...
Mitochondria are the main places of cellular respiration as well as the citric acid cycle and oxidative phosphorylation.It plays an important role in controlling the life and death of cells.Mitochondrial dysfunction leads to a series of human disease...
2015, 33(1): 5-8.
doi: 10.3969/j.issn.1006-0111.2015.01.002
Abstract:
This review made a brief summary of several pharmacokinetic methods of traditional Chinese medicine (TCM) prescription including the methods of biological effects,plasma concentration,integrated Pharmacokinetics of multiple effective components of TC...
This review made a brief summary of several pharmacokinetic methods of traditional Chinese medicine (TCM) prescription including the methods of biological effects,plasma concentration,integrated Pharmacokinetics of multiple effective components of TC...
2015, 33(1): 9-12,16.
doi: 10.3969/j.issn.1006-0111.2015.01.003
Abstract:
The delivery of therapeutical agents for brain tumors' treatment is enormously prevented by the presence of blood-brain barrier.Nano-carriers such as nano-particles,liposomes and micelles can significantly increase the transport of drugs across the b...
The delivery of therapeutical agents for brain tumors' treatment is enormously prevented by the presence of blood-brain barrier.Nano-carriers such as nano-particles,liposomes and micelles can significantly increase the transport of drugs across the b...
2015, 33(1): 13-16.
doi: 10.3969/j.issn.1006-0111.2015.01.004
Abstract:
Objective To summarize the advantage and application of evaporative light scattering detector(ELSD) for the analysis of natural drugs. Methods The application of ELSD in natural medicine analysis was reviewed in the article. Results ELSD in anal...
Objective To summarize the advantage and application of evaporative light scattering detector(ELSD) for the analysis of natural drugs. Methods The application of ELSD in natural medicine analysis was reviewed in the article. Results ELSD in anal...
2015, 33(1): 17-19,27.
doi: 10.3969/j.issn.1006-0111.2015.01.005
Abstract:
Monocyte locomotion inhibitory factor(MLIF)was an anti-inflammatory pentapeptide produced by Entamoeba histolytica.In vivo and in vitro study showed that MLIF displayed anti-inflammatory and immune protection effects and MLIF had protective effects o...
Monocyte locomotion inhibitory factor(MLIF)was an anti-inflammatory pentapeptide produced by Entamoeba histolytica.In vivo and in vitro study showed that MLIF displayed anti-inflammatory and immune protection effects and MLIF had protective effects o...
2015, 33(1): 20-27.
doi: 10.3969/j.issn.1006-0111.2015.01.006
Abstract:
Inflammation is the defense response of the living tissues possessing vascular system to stimulations of various injury factors,which plays a vital role in the initiation and progression of many major diseases.Drugs used to treat inflammation in the ...
Inflammation is the defense response of the living tissues possessing vascular system to stimulations of various injury factors,which plays a vital role in the initiation and progression of many major diseases.Drugs used to treat inflammation in the ...
2015, 33(1): 28-31,35.
doi: 10.3969/j.issn.1006-0111.2015.01.007
Abstract:
Objective To evaluate the therapeutic effects of Thesium chinensis Turcz extracts on IgA nephropathy (IgAN) rats. Methods The hot water extracted solution of Thesium chinensis Turcz flow through the AB-8 macroreticular resin column repeatedly,then...
Objective To evaluate the therapeutic effects of Thesium chinensis Turcz extracts on IgA nephropathy (IgAN) rats. Methods The hot water extracted solution of Thesium chinensis Turcz flow through the AB-8 macroreticular resin column repeatedly,then...
2015, 33(1): 32-35.
doi: 10.3969/j.issn.1006-0111.2015.01.008
Abstract:
Objective To study the bioequivalence of two kinds of levetiracetam extended-release tables including the reference product of Keppra XR in Beagle dogs. Methods Dogs were administrated orally with single dose of levetiracetam tablets (1 000 mg).Th...
Objective To study the bioequivalence of two kinds of levetiracetam extended-release tables including the reference product of Keppra XR in Beagle dogs. Methods Dogs were administrated orally with single dose of levetiracetam tablets (1 000 mg).Th...
2015, 33(1): 36-39,43.
doi: 10.3969/j.issn.1006-0111.2015.01.009
Abstract:
Objective To prepare and characterize salinomycin sodium-loaded nano liposomes(SLN). Methods The nano liposomes were prepared by a thin-film dispersion method.The formula of SLN was optimized by regulating the cholesterol ratio of the nano liposom...
Objective To prepare and characterize salinomycin sodium-loaded nano liposomes(SLN). Methods The nano liposomes were prepared by a thin-film dispersion method.The formula of SLN was optimized by regulating the cholesterol ratio of the nano liposom...
2015, 33(1): 40-43.
doi: 10.3969/j.issn.1006-0111.2015.01.010
Abstract:
Objective To establish a HPLC method for determination of related substances of risedronate sodium tablets. Methods The C18 column,5 μm,150 mm×4.6 mm,the buffer solution (3.22 g tetrabutyl ammonium bromide was added to a buffer solution of 1 000 m...
Objective To establish a HPLC method for determination of related substances of risedronate sodium tablets. Methods The C18 column,5 μm,150 mm×4.6 mm,the buffer solution (3.22 g tetrabutyl ammonium bromide was added to a buffer solution of 1 000 m...
2015, 33(1): 44-48.
doi: 10.3969/j.issn.1006-0111.2015.01.011
Abstract:
Objective To construct an active targeting drug delivery system- polymer vesicles(PVs),and examined the cellular uptake. Methods Maleimide-polyethylene glycol-poly(lactic-co-glycolic acid)(MAL-PEG-PLGA)was used as carrier materials to prepare PVs ...
Objective To construct an active targeting drug delivery system- polymer vesicles(PVs),and examined the cellular uptake. Methods Maleimide-polyethylene glycol-poly(lactic-co-glycolic acid)(MAL-PEG-PLGA)was used as carrier materials to prepare PVs ...
2015, 33(1): 49-52,71.
doi: 10.3969/j.issn.1006-0111.2015.01.012
Abstract:
Objective To analyze chemical constituents of Xionggui Decotion by rapid-resolution (high performance) liquid chromatography-time of flight mass spectrometry (HPLC-TOF-MS). Methods A Shelloseido column(100 mm×3.0 mm,3 μm)was used to separate.The m...
Objective To analyze chemical constituents of Xionggui Decotion by rapid-resolution (high performance) liquid chromatography-time of flight mass spectrometry (HPLC-TOF-MS). Methods A Shelloseido column(100 mm×3.0 mm,3 μm)was used to separate.The m...
2015, 33(1): 53-54,57.
doi: 10.3969/j.issn.1006-0111.2015.01.013
Abstract:
Objective To explore method for determination of calycosin contents in Wujin capsule by HPLC. Methods The sample was studied on ZORBA Bonus-RP (4.6 mm×260 mm,5 μm) column,the mobile phase consisted of acetonitrile and H2O-0.1% HCOOH (gradient elut...
Objective To explore method for determination of calycosin contents in Wujin capsule by HPLC. Methods The sample was studied on ZORBA Bonus-RP (4.6 mm×260 mm,5 μm) column,the mobile phase consisted of acetonitrile and H2O-0.1% HCOOH (gradient elut...
2015, 33(1): 55-57.
doi: 10.3969/j.issn.1006-0111.2015.01.014
Abstract:
Objective To establish the quantitative determination method of dexamethasone acetate in Kelaweiding liniment by HPLC. Methods Column:Diamonsil-C18(150 mm×4.6 mm,5 μm),mobile phase:methanol-water-glacialaceticacid (80:20:0.5),flow rate:1.0 ml/min,...
Objective To establish the quantitative determination method of dexamethasone acetate in Kelaweiding liniment by HPLC. Methods Column:Diamonsil-C18(150 mm×4.6 mm,5 μm),mobile phase:methanol-water-glacialaceticacid (80:20:0.5),flow rate:1.0 ml/min,...
2015, 33(1): 58-59,82.
doi: 10.3969/j.issn.1006-0111.2015.01.015
Abstract:
Objective To establish an HPLC method for assay determination of fluoxetine hydrochloride. Methods Agilent Eclipse XDB-C8 (4.6 mm × 250 mm,5 μm) was used,mobile phase was tetrahydrofuran-methanol-triethylamine buffer (to 10 ml of triethylamine in ...
Objective To establish an HPLC method for assay determination of fluoxetine hydrochloride. Methods Agilent Eclipse XDB-C8 (4.6 mm × 250 mm,5 μm) was used,mobile phase was tetrahydrofuran-methanol-triethylamine buffer (to 10 ml of triethylamine in ...
2015, 33(1): 60-62.
doi: 10.3969/j.issn.1006-0111.2015.01.016
Abstract:
Objective To optimize the preparation technology of compound Chuanxiong dropping pills. Methods Ratio of intermediate material to matrix,dripping temperature and condensate temperature were used as factors,with spherical degree,pill weight variatc...
Objective To optimize the preparation technology of compound Chuanxiong dropping pills. Methods Ratio of intermediate material to matrix,dripping temperature and condensate temperature were used as factors,with spherical degree,pill weight variatc...
2015, 33(1): 63-64,93.
doi: 10.3969/j.issn.1006-0111.2015.01.017
Abstract:
Objective To study the stability of sodium nitroprusside for injection in 5% glucose injection and 0.9% sodium chloride injection,and provide reference for clinical rational drug use. Methods The content of sodium nitroprusside for injection in di...
Objective To study the stability of sodium nitroprusside for injection in 5% glucose injection and 0.9% sodium chloride injection,and provide reference for clinical rational drug use. Methods The content of sodium nitroprusside for injection in di...
2015, 33(1): 65-67.
doi: 10.3969/j.issn.1006-0111.2015.01.018
Abstract:
Objective To analyze the occurrence rate of gastrointestinal and pulmonary infection and hospital acquired pneumonia (HAP)in severe craniocerebral injuries in my hospital using proton pump inhibitors (PPIs),discuss the right way to use PPIs for seve...
Objective To analyze the occurrence rate of gastrointestinal and pulmonary infection and hospital acquired pneumonia (HAP)in severe craniocerebral injuries in my hospital using proton pump inhibitors (PPIs),discuss the right way to use PPIs for seve...
2015, 33(1): 68-71.
doi: 10.3969/j.issn.1006-0111.2015.01.019
Abstract:
Objective To report experience on pharmaceutical care in a renal transplantation recipient with herpes zoster. Methods The methods and measures of pharmaceutical care of a renal transplantation recipient with herpes zoster were retrospectively sum...
Objective To report experience on pharmaceutical care in a renal transplantation recipient with herpes zoster. Methods The methods and measures of pharmaceutical care of a renal transplantation recipient with herpes zoster were retrospectively sum...
2015, 33(1): 72-72,87.
doi: 10.3969/j.issn.1006-0111.2015.01.020
Abstract:
Objective To observe adverse reactions of the subcutaneous etanercept with different injection site. Methods 60 patients with ankylosing spondylitis treated in our hospital from March 2012 to March 2013 were divided randomly into two groups.A grou...
Objective To observe adverse reactions of the subcutaneous etanercept with different injection site. Methods 60 patients with ankylosing spondylitis treated in our hospital from March 2012 to March 2013 were divided randomly into two groups.A grou...
2015, 33(1): 73-75.
doi: 10.3969/j.issn.1006-0111.2015.01.021
Abstract:
Objective To investigate the rationality of prophylactic use of anti-bacterial in 251 type Ⅰ incision operations. Methods The anti-bacterial use of 251 type Ⅰ incision operations sampled randomly from May 2012 to May 2013 were retrospectively anal...
Objective To investigate the rationality of prophylactic use of anti-bacterial in 251 type Ⅰ incision operations. Methods The anti-bacterial use of 251 type Ⅰ incision operations sampled randomly from May 2012 to May 2013 were retrospectively anal...
2015, 33(1): 76-79.
doi: 10.3969/j.issn.1006-0111.2015.01.022
Abstract:
Objective To investigate the utility of antibiotics in elderly patients of respiratory department in No.210 Hospital of PLA,and to understand the rational use of antibiotics in respiratory department. Methods A total of 534 patients >60 in respira...
Objective To investigate the utility of antibiotics in elderly patients of respiratory department in No.210 Hospital of PLA,and to understand the rational use of antibiotics in respiratory department. Methods A total of 534 patients >60 in respira...
2015, 33(1): 80-82.
doi: 10.3969/j.issn.1006-0111.2015.01.023
Abstract:
Objective To evaluate two treatment schemes of liver protection and choose the optimal radiotherapy using pharmacoeconomics principle and methods. Methods In-patients who were diagnosed as decompensated cirrhosis patients and simultaneously confor...
Objective To evaluate two treatment schemes of liver protection and choose the optimal radiotherapy using pharmacoeconomics principle and methods. Methods In-patients who were diagnosed as decompensated cirrhosis patients and simultaneously confor...
2015, 33(1): 83-87.
doi: 10.3969/j.issn.1006-0111.2015.01.024
Abstract:
Objective To assess the effectiveness of western routine treatments combined with Tongxinluo capsule for angina pectoris. Methods The randomized controlled trials(RCTs) of western routine treatments combined with tongxinluo capsule for angina pect...
Objective To assess the effectiveness of western routine treatments combined with Tongxinluo capsule for angina pectoris. Methods The randomized controlled trials(RCTs) of western routine treatments combined with tongxinluo capsule for angina pect...
2015, 33(1): 88-90.
doi: 10.3969/j.issn.1006-0111.2015.01.025
Abstract:
Objective To discuss the important role of clinical pharmacists in medication reconciliation through the practice of clinical pharmacists of nephrology department. Methods The medication reconciliation serviced for the patients newly admitted to n...
Objective To discuss the important role of clinical pharmacists in medication reconciliation through the practice of clinical pharmacists of nephrology department. Methods The medication reconciliation serviced for the patients newly admitted to n...
2015, 33(1): 91-93.
doi: 10.3969/j.issn.1006-0111.2015.01.026
Abstract:
Objective To contrast the different specialties of clinical pharmacists in internal medicine and surgery and guide the direction for clinical pharmacists to work deeply. Methods The clinical pharmacist's work records were reviewed and summarized i...
Objective To contrast the different specialties of clinical pharmacists in internal medicine and surgery and guide the direction for clinical pharmacists to work deeply. Methods The clinical pharmacist's work records were reviewed and summarized i...
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