2013 Vol. 31, No. 5
Display Method:
2013, 31(5): 321-325,379.
doi: 10.3969/j.issn.1006-0111.2013.05.001
Abstract:
Objective To review recent progress of antifungal drug targets and their inhibitors. Methods Literatures in recent five years were analyzed in combination of the authors'own research work and recent developments of antifungal targets and inhibitors...
Objective To review recent progress of antifungal drug targets and their inhibitors. Methods Literatures in recent five years were analyzed in combination of the authors'own research work and recent developments of antifungal targets and inhibitors...
2013, 31(5): 326-329.
doi: 10.3969/j.issn.1006-0111.2013.05.002
Abstract:
In recent years, the increasing incidence of ischemic disease, especially for myocardial ischemia and other vascular diseases had become one of the most important causes of human death. Therapeutic angiogenesis attracted many scientists' attention, a...
In recent years, the increasing incidence of ischemic disease, especially for myocardial ischemia and other vascular diseases had become one of the most important causes of human death. Therapeutic angiogenesis attracted many scientists' attention, a...
2013, 31(5): 330-333,350.
doi: 10.3969/j.issn.1006-0111.2013.05.003
Abstract:
The lack of folic acid which could cause hyperhomocysteine had revealed an obviously relationship with cardiovascular and cerebrovascular diseases. Plenty of studies had shown that hyperhomocysteine was an independent risk factor of cardiovascular an...
The lack of folic acid which could cause hyperhomocysteine had revealed an obviously relationship with cardiovascular and cerebrovascular diseases. Plenty of studies had shown that hyperhomocysteine was an independent risk factor of cardiovascular an...
2013, 31(5): 334-337.
doi: 10.3969/j.issn.1006-0111.2013.05.004
Abstract:
Objective To evaluate the differential proteomics of human keratinocytes with transient receptor potential vanilloid-1(TRPV1) activated by capsaicin. Methods Human keratinocytes were cultured and treated by capsaicin. Two-dimensional polyacrylamide...
Objective To evaluate the differential proteomics of human keratinocytes with transient receptor potential vanilloid-1(TRPV1) activated by capsaicin. Methods Human keratinocytes were cultured and treated by capsaicin. Two-dimensional polyacrylamide...
2013, 31(5): 338-343,346.
doi: 10.3969/j.issn.1006-0111.2013.05.005
Abstract:
Objective To establish a population pharmacokinetic (PPK) model of metformin in healthy Chinese subjects, and evaluate the effect of different physiological factors on pharmacokinetic parameters of metformin. Methods A single dose, open label PK st...
Objective To establish a population pharmacokinetic (PPK) model of metformin in healthy Chinese subjects, and evaluate the effect of different physiological factors on pharmacokinetic parameters of metformin. Methods A single dose, open label PK st...
2013, 31(5): 344-346.
doi: 10.3969/j.issn.1006-0111.2013.05.006
Abstract:
Objective To develop and evaluate the stable method for the determination of impurity D (kanamycin) in amikacin sulfate injection with pre-column derivatization HPLC. Methods The lower concentration of sample was used. An Agilent ZORBAX SB-C18 col...
Objective To develop and evaluate the stable method for the determination of impurity D (kanamycin) in amikacin sulfate injection with pre-column derivatization HPLC. Methods The lower concentration of sample was used. An Agilent ZORBAX SB-C18 col...
2013, 31(5): 347-350.
doi: 10.3969/j.issn.1006-0111.2013.05.007
Abstract:
Objective To construct the recombinant adenovirus expression vector containing ribosomal protein RPS3a and detect its expression in NIH3T3 cells. Method The RPS3a gene was obtained by RT-PCR.,total RNA was extracted from human HEK293 cell as the t...
Objective To construct the recombinant adenovirus expression vector containing ribosomal protein RPS3a and detect its expression in NIH3T3 cells. Method The RPS3a gene was obtained by RT-PCR.,total RNA was extracted from human HEK293 cell as the t...
2013, 31(5): 351-354.
doi: 10.3969/j.issn.1006-0111.2013.05.008
Abstract:
Objective To study the chemical constituents and antioxidant activityof the root tubers of Cynanchum auriculatum Royle ex Wight (asclepiadaceae). Methods The root tubers were extracted with 95% EtOH, and the ethanol extract was further separated an...
Objective To study the chemical constituents and antioxidant activityof the root tubers of Cynanchum auriculatum Royle ex Wight (asclepiadaceae). Methods The root tubers were extracted with 95% EtOH, and the ethanol extract was further separated an...
2013, 31(5): 355-356.
doi: 10.3969/j.issn.1006-0111.2013.05.009
Abstract:
Objective To observe clinical efficacy of budesonide suspension for inhalation (pulmicort respules) for treatment of upper airway cough syndrome. Methods The treatment group(31 patients) used 1mg budesonide suspension for inhalation partly by atomi...
Objective To observe clinical efficacy of budesonide suspension for inhalation (pulmicort respules) for treatment of upper airway cough syndrome. Methods The treatment group(31 patients) used 1mg budesonide suspension for inhalation partly by atomi...
2013, 31(5): 357-358,395.
doi: 10.3969/j.issn.1006-0111.2013.05.010
Abstract:
Objective To evaluate the value and safety of combined therapy of growth hormone and gonadotropin on male delayed puberty caused by hypogonadotropic hypogonadism. Methods A retrospective analysis was undergoing in Shanghai First Maternity and Infan...
Objective To evaluate the value and safety of combined therapy of growth hormone and gonadotropin on male delayed puberty caused by hypogonadotropic hypogonadism. Methods A retrospective analysis was undergoing in Shanghai First Maternity and Infan...
2013, 31(5): 359-361,365.
doi: 10.3969/j.issn.1006-0111.2013.05.011
Abstract:
Objective To study the effect of butenafine on ergosterol biosynthesis in fungi by measuring incorporation of nuclide. Methods The inhibitory effect of butenafine on ergosterol biosynthesis in whole-cell fungi was studied by measuring the incorpora...
Objective To study the effect of butenafine on ergosterol biosynthesis in fungi by measuring incorporation of nuclide. Methods The inhibitory effect of butenafine on ergosterol biosynthesis in whole-cell fungi was studied by measuring the incorpora...
2013, 31(5): 362-365.
doi: 10.3969/j.issn.1006-0111.2013.05.012
Abstract:
Objective To study the antioxidant effects of grape seed proanthocyanidins phospholipid complex(GSPPC). Methods Eighty rats were randomly divided into eight groups: normal control, model control, Proanthocyanidins, Soybean phospholipids, Vitamin C ...
Objective To study the antioxidant effects of grape seed proanthocyanidins phospholipid complex(GSPPC). Methods Eighty rats were randomly divided into eight groups: normal control, model control, Proanthocyanidins, Soybean phospholipids, Vitamin C ...
2013, 31(5): 366-367,383.
doi: 10.3969/j.issn.1006-0111.2013.05.013
Abstract:
Objective To prepare ropivacaine hydrochloride thermosensitive gel injection and establish the determination methods of contents. Methods Ropivacaine hydrochloride thermosensitive gel injection was prepared by cold methods with poloxamer as thermos...
Objective To prepare ropivacaine hydrochloride thermosensitive gel injection and establish the determination methods of contents. Methods Ropivacaine hydrochloride thermosensitive gel injection was prepared by cold methods with poloxamer as thermos...
2013, 31(5): 368-370.
doi: 10.3969/j.issn.1006-0111.2013.03.014
Abstract:
Objective To establish a method for determining the microbial assays of doxycycline by turbidimetric method in order to provide a basis for further development. Methods Staphylococcus aureus was chosen as the test organism that the microbiological ...
Objective To establish a method for determining the microbial assays of doxycycline by turbidimetric method in order to provide a basis for further development. Methods Staphylococcus aureus was chosen as the test organism that the microbiological ...
2013, 31(5): 371-372,400.
doi: 10.3969/j.issn.1006-0111.2013.05.015
Abstract:
Objective To study the alcohol-soluble component abstraction procedure of Xinshu Granula. Methods The optional extraction process was selected for the yields of extracts & Tanshinone ⅡA by using L9(34) orthogonal design.The effects of alcohol conce...
Objective To study the alcohol-soluble component abstraction procedure of Xinshu Granula. Methods The optional extraction process was selected for the yields of extracts & Tanshinone ⅡA by using L9(34) orthogonal design.The effects of alcohol conce...
2013, 31(5): 373-376.
doi: 10.3969/j.issn.1006-0111.2013.05.016
Abstract:
Objective To design and synthesis novel triazole antifungal derivatives and study the antifungal activity. Methods All the target compounds were prepared from 1,3-difluorobenzene via click reaction;The antibacterial activities of the title compound...
Objective To design and synthesis novel triazole antifungal derivatives and study the antifungal activity. Methods All the target compounds were prepared from 1,3-difluorobenzene via click reaction;The antibacterial activities of the title compound...
2013, 31(5): 377-379.
doi: 10.3969/j.issn.1006-0111.2013.05.017
Abstract:
Objective To improve the synthetic process of 2-methyl-5-methoxy benzoic acid ethyl ester. Methods The target compounds were prepared from 2-methyl-5-nitro-benzoic acid through esterification, reduction, diazotization hydrolysis and methylation. R...
Objective To improve the synthetic process of 2-methyl-5-methoxy benzoic acid ethyl ester. Methods The target compounds were prepared from 2-methyl-5-nitro-benzoic acid through esterification, reduction, diazotization hydrolysis and methylation. R...
2013, 31(5): 380-383.
doi: 10.3969/j.issn.1006-0111.2013.05.018
Abstract:
Objective To establish a method for the simultaneous determination of vitamin C and vitamin B1 in ferrous fumarate granules. Methods The procedure was performed on the Insteril ODS-3 C18 column at 30℃, detected at 244 nm. The mobile phase was compo...
Objective To establish a method for the simultaneous determination of vitamin C and vitamin B1 in ferrous fumarate granules. Methods The procedure was performed on the Insteril ODS-3 C18 column at 30℃, detected at 244 nm. The mobile phase was compo...
2013, 31(5): 384-385,392.
doi: 10.3969/j.issn.1006-0111.2013.05.019
Abstract:
Objective To develop a method for determination of assiticoside in Centella asiatica and its formula particles. Methods Hypersil ODS C18 column was used(4.6 mmá250 mm,5 μm),withacetonitrile-water(v/v=3:8) as mobile phase, and a flow rate of 0.6 ml/...
Objective To develop a method for determination of assiticoside in Centella asiatica and its formula particles. Methods Hypersil ODS C18 column was used(4.6 mmá250 mm,5 μm),withacetonitrile-water(v/v=3:8) as mobile phase, and a flow rate of 0.6 ml/...
2013, 31(5): 386-387.
doi: 10.3969/j.issn.1006-0111.2013.05.020
Abstract:
Objective To establish a HPLC method for determination of stilbene glucoside in Yangxueanshen Pills. Methods The Waters C18 column (4.6 mm×250 mm, 5 μm) was used. The mobile phase was acetonitrile-water (20:80).The flow rate was 1.0 ml/min.The det...
Objective To establish a HPLC method for determination of stilbene glucoside in Yangxueanshen Pills. Methods The Waters C18 column (4.6 mm×250 mm, 5 μm) was used. The mobile phase was acetonitrile-water (20:80).The flow rate was 1.0 ml/min.The det...
2013, 31(5): 388-389.
doi: 10.3969/j.issn.1006-0111.2013.05.021
Abstract:
Objective To study the validity and affordability between joint venture entercavier and domestic entercavier in treating patients with chronic hepatitis B. Methods 65 patients with chronic hepatitis B were select who were treated with entercavier b...
Objective To study the validity and affordability between joint venture entercavier and domestic entercavier in treating patients with chronic hepatitis B. Methods 65 patients with chronic hepatitis B were select who were treated with entercavier b...
2013, 31(5): 390-392.
doi: 10.3969/j.issn.1006-0111.2013.05.022
Abstract:
Objective To summarize the experience and lessens after intervention in outpatient return drugs process. Methods Return-drugs prescriptions in 2011 and 2012 in our hospital were retrospectively analyzed, focusing on reasons of return drugs events a...
Objective To summarize the experience and lessens after intervention in outpatient return drugs process. Methods Return-drugs prescriptions in 2011 and 2012 in our hospital were retrospectively analyzed, focusing on reasons of return drugs events a...
2013, 31(5): 393-395.
doi: 10.3969/j.issn.1006-0111.2015.03.023
Abstract:
Objective To evaluate and analyze the prescription writing and irrational drug uses in order to improve the quality of prescription and promote rational drug use in clinic. Methods 14 872 pieces of prescriptions were randomly selected one day per m...
Objective To evaluate and analyze the prescription writing and irrational drug uses in order to improve the quality of prescription and promote rational drug use in clinic. Methods 14 872 pieces of prescriptions were randomly selected one day per m...
2013, 31(5): 396-397.
doi: 10.3969/j.issn.1006-0111.2013.05.024
Abstract:
Objective To improve the ability of medical material service in contract tactical maneuver in order to prevent the drug backlog and out-dated. Method The medical material services in contract tactical maneuver in recent years were analyzed. The pl...
Objective To improve the ability of medical material service in contract tactical maneuver in order to prevent the drug backlog and out-dated. Method The medical material services in contract tactical maneuver in recent years were analyzed. The pl...
2013, 31(5): 398-400.
doi: 10.3969/j.issn.1006-0111.2013.05.025
Abstract:
Objective To build up the teaching tactics of research in the current organic chemistry course teaching for pharmic students,promote the ability of practicing and innovation,discuss how to accommodate the development of modern pharmacy education. Me...
Objective To build up the teaching tactics of research in the current organic chemistry course teaching for pharmic students,promote the ability of practicing and innovation,discuss how to accommodate the development of modern pharmacy education. Me...
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