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2013 Vol. 31, No. 4

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Proteomics in study of traditional Chinese medicine
LI Min, JIANG Peng, WANG Shu-ping, HAN Lin, HUANG Hui-mei, CHANG Wan-lin, LIU Run-hui
2013, 31(4): 241-245. doi: 10.3969/j.issn.1006-0111.2013.04.001
Abstract(4356) PDF (724KB)(121)
Abstract:
Systems biology focused on constitute dynamic and development of system components, which was consistent with traditional Chinese medicine as a whole and dynamic adjustment to the body. It brought the dawn to reveal the mystery of TCM. As an importan...
Clinical pharmacology in the prophylaxis and treatment of high-altitude illness
MA Jun, FAN Peng-cheng, ZHANG Qiang, MA Hui-ping, WANG Rong, JIA Zheng-ping
2013, 31(4): 246-250. doi: 10.3969/j.issn.1006-0111.2013.04.002
Abstract:
The use choice of acetazolamide, dexamethasone, nifedipine, sildenafil, and salmeterol in the management of altitude illness such as acute mountain sickness, high-altitude cerebral edema, high-altitude pulmonary edema, and with underlying medical pro...
Application of in situ gel in cancer therapy
FAN Li, HE Wen-ting, GAO Shen
2013, 31(4): 251-253,285. doi: 10.3969/j.issn.1006-0111.2013.04.003
Abstract(2828) PDF (541KB)(242)
Abstract:
In situ gel has shown special advantages in cancer therapy due to high local drug concentration and convenient administration, which made it be promising in future clinical application. In this paper, the application of in situ gel in different tumor...
Chemical constituents and pharmacological research on Cremanthodium
FAN Xiao-fei, JING Lin-lin, GAO Rong-min, JIA Zheng-ping
2013, 31(4): 254-257,282. doi: 10.3969/j.issn.1006-0111.2013.03.004
Abstract(1110) PDF (752KB)(323)
Abstract:
Objective Cremanthodium genus had been proved to have good biological activity and attracted more and more scholars attention.Several plants of Cremanthodium genus had been used as Tibetan traditional herbal medicine to treat fever, inflammation, pa...
Preparation of nicardipine hydrochloride sustained-release pellets
YUAN Li-hui, BIAN Jun
2013, 31(4): 258-261. doi: 10.3969/j.issn.1006-0111.2013.04.005
Abstract(3149) PDF (706KB)(513)
Abstract:
Objective To prepare nicardipine hydrochloride sustained-release pellets and investigate the influencing factors of the drug release in vitro. Methods The rapid-release pellets were prepared by fluidized bed coating method based on blank pill core...
Effect of icariin and curculigoside on inhibition of osteoclastic formation, differentiation and bone absorption
GUO Yuan-hui, XUE Li-ming, NIE Yan, WANG Ying, ZHAO Lu, QIN Lu-Ping, ZHANG Qiao-yan, YU Yuan
2013, 31(4): 262-266. doi: 10.3969/j.issn.1006-0111.2013.04.006
Abstract(4263) PDF (901KB)(596)
Abstract:
Objective To investigate the interaction relationship of icariin and curculigoside on the osteoclastic formation, differentiation and bone resorbing. Methods Multinucleated osteoclasts were induced by 1, 25-dihydroxyvitamine D3 and dexamethasone fr...
Seasonal dynamics and tissue distribution of endophytic fungi in Cephalotaxus fortunei Hook. f.
XIANG Yan-ying, MING Qian-liang, LI Wen-chao, HAN Ting, QIN Lu-ping
2013, 31(4): 267-270,289. doi: 10.3969/j.issn.1006-0111.2013.04.007
Abstract:
Objective To investigated the species composition, number and distribution of endophytes in medicinal plants Cephalotaxus fortunei Hook. f. in different seasons and different tissues. Methods Endophytic fungi were isolated by tissue-culture method...
The damage compensation for participants in clinical trail in USA
SHEN Yu-hong, ZHANG Zheng-fu, LI Zheng-qi
2013, 31(4): 271-272,276. doi: 10.3969/j.issn.1006-0111.2013.04.008
Abstract(3187) PDF (508KB)(455)
Abstract:
Objective To give advice and reference for establishment of compensation mechanism of drug clinical trial subjects in China. Methods The drug clinical trials to the subjects' impairment of the determination and compensation scheme liability in USA...
Qualitative and quantitative analysis of metronidazole injection solutions by confocal microprobe Raman spectroscopy
YANG Ming-hua, SUN Xue-mei, CHEN Gui-liang, ZHANG Yu-min
2013, 31(4): 273-276. doi: 10.3969/j.issn.1006-0111.2013.04.009
Abstract:
Objective To explore the application of Raman spectroscopy in metronidazole injection solution analysis. Methods The variation of metronidazole (MET) injections' Raman spectra was analyzed when the pH varied from 1 to 12, and the related substance...
Determination of sterols in Candida albicans by GC-SIM-MS
WANG Tian-qi, LI Xiang, LI Ling, WU Hai-tang, XU Li
2013, 31(4): 277-279,320. doi: 10.3969/j.issn.1006-0111.2013.04.010
Abstract(3466) PDF (498KB)(331)
Abstract:
Objective To establish a method of GC-SIM-MS for the determination of sterols in Candida albicans, including lanosterol and ergosterol. Methods The sterols extracted from Candida albicans were analyzed by gas chromatography with a HP 50 capillary ...
Study on the hypolipidemic effects of polydatin
GAO Yue, JI Qian
2013, 31(4): 280-282. doi: 10.3969/j.issn.1006-0111.2013.04.011
Abstract:
Objective To investigate the hypolipidemic effects of polydatin on hyperlipidemic animals. Methods The models of hyperlipidemic rabbits and rats were established. Model animals were orally given polydatin for continuous 7 or 14 days and the serum ...
The influence of butylphthalide on amino acid in epileptic mice's brain
HAN Lin
2013, 31(4): 283-285. doi: 10.3969/j.issn.1006-0111.2013.04.012
Abstract:
Objective Aim to investigate the influence of butylphthalide (NBP) on amino acid content in epileptic mice's brain. Methods NBP was intraperitoneally injected (ip) mice and acute epileptic mice models were made after 30 min. The change of the four...
Optimization of preparation of matrine liposome in ammonium sulfate gradient method by orthogonal experiment
LI Sha, WU Wen-ying, XU Xiao-na, LI Xing-hua, MA Xiao-ya
2013, 31(4): 286-289. doi: 10.3969/j.issn.1006-0111.2013.04.013
Abstract(3784) PDF (713KB)(309)
Abstract:
Objective To study the preparation method of matrine liposome and screen the optimal technological conditions by the encapsulation efficiencies. Methods Liposome was made of hydrogenated soybean phosphatidylcholine (HSPC) and cholesterol (Ch) by fi...
Study on stability of tinidazole and spironolactone cream
PENG Xian-dong, LONG Feng, TANG Zhi-li, XIE Jun
2013, 31(4): 290-292,299. doi: 10.3969/j.issn.1006-0111.2013.04.014
Abstract(3154) PDF (559KB)(217)
Abstract:
Objective To study the stability of tinidazole and spironolactone cream. Methods The content of tinidazole and spironolactone in cream were determined simultaneously by HPLC, and the period of validity of tinidazole spironolactone cream was predic...
Selection of auxiliary material of nature based for Compound Danshen Dropping Pills
SUN Qing, ZHANG Xiao-jie, WANG Wei
2013, 31(4): 293-295. doi: 10.3969/j.issn.1006-0111.2013.04.015
Abstract(3166) PDF (431KB)(107)
Abstract:
Objective To explore a new pure nature based auxiliary material for Compound Danshen Dropping Pills. Methods A single herbal auxiliary material was used to produce Compound Danshen Dropping Pills.Then two auxiliary materials were mixed to produce ...
Simultaneous determination of contents of four components in three different dosage forms of Liuweidihuang by HPLC
WANG Ling-xia, ZHU Dong-liang, CHAI Yi-feng
2013, 31(4): 296-299. doi: 10.3969/j.issn.1006-0111.2013.04.016
Abstract:
Objective To develop a new high performance liquid chromatography (HPLC) method for simultaneous determination of four major components (gallic acid, loganin, paeoniflorin and paeonol) in different dosage forms of Liuweidihuang. Methods The chroma...
Determination of chlorogenic acid and hesperidin in Lishi Oral Liquid by HPLC
CHU Zhong-ying, WU Li-hong, XU Hong-yan
2013, 31(4): 300-301,317. doi: 10.3969/j.issn.1006-0111.2013.04.017
Abstract:
Objective To establish a method for determining chlorogenic acid and hesheridin in Lishi Oral Liquid (Plantaginis Herba, Kochiate Frouctus, Lonicerae Japonicae Flos, Sophorpe Flavescentis Radix, Citri Reticulatae Pericarpium, Poriae Cutis, Maifahitu...
Determination of contents of ginsenoside Rg1, Re and Rb1 in Naili capsule Nov. 3 by HPLC
WANG Yan-an, WANG Xiao-bo, Liu dan, XI Rong-gang
2013, 31(4): 302-303,309. doi: 10.3969/j.issn.1006-0111.2013.04.018
Abstract:
Objective To establish a method for the determination of ginsenoside Rg1、ginsenoside Re、ginsenoside Rb1 in Naili capsule Nov. 3. Methods HPLC with C18 column was revised to control the content of Radix Panax quinguefolium, the detective wavelength ...
Case analysis of drug treatment of intra-cerebral hemorrhage patients in ICU participated by clinical pharmacists
TIAN Jing, WANG Zhou, LI Li-xia
2013, 31(4): 304-306,313. doi: 10.3969/j.issn.1006-0111.2013.04.019
Abstract(2905) PDF (661KB)(182)
Abstract:
Objective To explore the method of participating in designing therapy regimens and carrying out pharmaceutical care for clinical pharmacists. Methods The clinical pharmacists participated in therapy of a patient with severe hospital-acquired pneumo...
Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma
FAN Rong, DANG Da-sheng, ZHAO Qing-chun, SHI Guo-bing
2013, 31(4): 307-309. doi: 10.3969/j.issn.1006-0111.2013.04.020
Abstract:
Objective To discuss the service mode, contents of pharmaceutical care and the basic knowledge and skills that a clinical pharmacist should master by participating in treatment of visual impairment caused by voriconazole in a patient of multiple mye...
Study on social and administrative pharmacy graduate curriculum program based on competencies
SHU li-xin, CHEN jing, LUAN zhi-peng, LI jie-wei
2013, 31(4): 310-313. doi: 10.3969/j.issn.1006-0111.2013.04.021
Abstract(2842) PDF (787KB)(121)
Abstract:
Objective To establish the social and administrative pharmacy graduate curriculum program. Methods systems analysis, expert interviews and literature research method were used to study graduate competency and education curriculum. Results Social a...
Comparison of different experts' opinions about pharmaceutical specialists' credentials for military superior technical position
LU Juan, HUANG Wei-can, WANG Yue
2013, 31(4): 314-317. doi: 10.3969/j.issn.1006-0111.2013.04.022
Abstract(2751) PDF (548KB)(258)
Abstract:
Objective To compare different experts' opinions about pharmaceutical specialists'credentials for military superior technical position. Methods Delphi method was taken to organize two rounds of specialist consultations, the final opinions of speci...
Exploration of Clinical Training for the trainee from Traditional Pharmacy undergraduates
HUO Yan, ZHANG Jian-ping, LU Yao-hua, GUO Cheng
2013, 31(4): 318-320. doi: 10.3969/j.issn.1006-0111.2013.04.023
Abstract:
Objective The demands of hospital pharmacists are changing now according to the new pharmaceutical care mode. The pattern and contents of the clinical training need to be altered to adapt to the hospital working environment when the undergraduates o...