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Th2相关炎症因子在湿疹发病中的作用机制

朱聪聪 潘会君 朱全刚

朱聪聪, 潘会君, 朱全刚. Th2相关炎症因子在湿疹发病中的作用机制[J]. 药学实践与服务, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
引用本文: 朱聪聪, 潘会君, 朱全刚. Th2相关炎症因子在湿疹发病中的作用机制[J]. 药学实践与服务, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
ZHU Congcong, PAN Huijun, ZHU Quangang. Mechanism of Th2 related inflammatory factors in the pathogenesis of eczema[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
Citation: ZHU Congcong, PAN Huijun, ZHU Quangang. Mechanism of Th2 related inflammatory factors in the pathogenesis of eczema[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003

Th2相关炎症因子在湿疹发病中的作用机制

doi: 10.3969/j.issn.1006-0111.2019.01.003
基金项目: 上海市科委资助项目(17401901800)

Mechanism of Th2 related inflammatory factors in the pathogenesis of eczema

  • 摘要: 湿疹是临床常见的炎症性皮肤病,具有剧烈瘙痒、反复发作等特点。其病因复杂,包括多种内、外因素相互作用。主要发病机制与Th2免疫应答失衡有关,相关的炎症因子更是发挥十分重要的作用。上皮衍生因子胸腺基质淋巴细胞生成素以及白介素-33(IL-33)能够引发Th2免疫失衡,促进IL-4、IL-5、IL-13等炎症因子分泌,后者进一步诱导嗜酸性粒细胞增多、IgE生成。综述Th2相关炎症因子在湿疹发病中的作用机制,对湿疹治疗具有重要意义。
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  • 收稿日期:  2018-09-28
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Th2相关炎症因子在湿疹发病中的作用机制

doi: 10.3969/j.issn.1006-0111.2019.01.003
    基金项目:  上海市科委资助项目(17401901800)

摘要: 湿疹是临床常见的炎症性皮肤病,具有剧烈瘙痒、反复发作等特点。其病因复杂,包括多种内、外因素相互作用。主要发病机制与Th2免疫应答失衡有关,相关的炎症因子更是发挥十分重要的作用。上皮衍生因子胸腺基质淋巴细胞生成素以及白介素-33(IL-33)能够引发Th2免疫失衡,促进IL-4、IL-5、IL-13等炎症因子分泌,后者进一步诱导嗜酸性粒细胞增多、IgE生成。综述Th2相关炎症因子在湿疹发病中的作用机制,对湿疹治疗具有重要意义。

English Abstract

朱聪聪, 潘会君, 朱全刚. Th2相关炎症因子在湿疹发病中的作用机制[J]. 药学实践与服务, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
引用本文: 朱聪聪, 潘会君, 朱全刚. Th2相关炎症因子在湿疹发病中的作用机制[J]. 药学实践与服务, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
ZHU Congcong, PAN Huijun, ZHU Quangang. Mechanism of Th2 related inflammatory factors in the pathogenesis of eczema[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
Citation: ZHU Congcong, PAN Huijun, ZHU Quangang. Mechanism of Th2 related inflammatory factors in the pathogenesis of eczema[J]. Journal of Pharmaceutical Practice and Service, 2019, 37(1): 9-13. doi: 10.3969/j.issn.1006-0111.2019.01.003
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