Efficacy of budesonide suspension for inhalation in the treatment of upper airway cough syndrome
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摘要: 目的 观察吸入用布地奈德混悬液(普米克令舒)治疗成人上气道咳嗽综合征的临床疗效。 方法 治疗组31例患者使用吸入布地奈德混悬液1 mg经面罩口鼻雾化吸入,每日2次,2周1疗程。对照组30例患者不使用激素。两组同时加入:口服氯雷他定10 mg,每日1次,吉诺通胶囊300 mg,每日3次,2周1疗程。两组用药连续2疗程。观察两组患者治疗前后症状变化。 结果 治疗组患者总体疗效的有效率为96.8%,明显优于对照组53.3%,统计学有差异(P<0.05)。 结论 布地奈德混悬液雾化吸入治疗上气道咳嗽综合征疗效明显,且起效时间和疗效均高于对照组。Abstract: Objective To observe clinical efficacy of budesonide suspension for inhalation (pulmicort respules) for treatment of upper airway cough syndrome. Methods The treatment group(31 patients) used 1mg budesonide suspension for inhalation partly by atomization inhalation via mask nose and mouth, which were used 2 times a day and course of two weeks. The control group (30 patients) were not used budesonide aerosol at all. At the same time, the two groups were added in oral loratadine 1 time a day and gino capsule 3 times a day and course of two weeks. Symptoms changes of twogroups used medication for 2 courses were observed before and after treatment. Results The overall effect of the patients treated with an effective rate of 96.8%, significantly better than the control group, which had a effective rate of 53.3%. (P<0.05). Conclusions Treatment of upper airway cough syndrome by aerosol inhalation budesonide suspension was effective, and the onset time and efficacy were higher than that in the control group.
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[1] 中华医学会呼吸病学分会哮喘学组. 咳嗽的诊断与治疗指南(2009版)[J].中华结核和呼吸杂志,2009,32:407. [2] 中华医学会儿科学分会呼吸学组,中华儿科杂志编辑委员会.儿童慢性咳嗽诊断与治疗指南(试行)[J].中华儿科杂志,2008,46:104. [3] Pratter MR. Chronic upper airway cough syndrome secondary to rhinosinus diseases (previously referred to as posmasal drip syndrome): ACCP evidence-based clinical practice guidelines[J]. Chest, 2006, 129(1 Suppl):63S. [4] 喻清和,邱志南. 中西医结合治疗小儿鼻后滴漏致慢性咳嗽疗效观察[J]. 中医药学刊, 2006, 24 (12): 2353. [5] 谷庆隆,陆颖霞,庞 冲,等.儿童难治性咳嗽128例病因分析[J].中华耳鼻咽喉头颈外科杂志.2010,45(1):28. [6] 时翠芹,余 莉,魏为利,等.气道炎症在上气道咳嗽综合征发生中的作用[J].中国呼吸与危重监护杂志.2009,8(3):256. -
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