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ZHANG Yihan, BIAN Yanfang. Concentration measurement of the quercetin in Folium Apocyni Veneti from various commercial markets and harvest time[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(1): 67-69. doi: 10.3969/j.issn.1006-0111.2017.01.016
Citation: ZHANG Yihan, BIAN Yanfang. Concentration measurement of the quercetin in Folium Apocyni Veneti from various commercial markets and harvest time[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(1): 67-69. doi: 10.3969/j.issn.1006-0111.2017.01.016

Concentration measurement of the quercetin in Folium Apocyni Veneti from various commercial markets and harvest time

doi: 10.3969/j.issn.1006-0111.2017.01.016
  • Received Date: 2015-08-29
  • Rev Recd Date: 2015-12-26
  • Objective To determine the quercetin content in Folium Apocyni Veneti from different commercial markets and harvest time by HPLC. Methods The determination was performed on an Aglient Eclipse XDB-C18 column (250 mm×4.6 mm,5 μm)at 30℃ with a mobile phase composed of Methanol:0.1% phosphoric acid run at gradient elution; the detection wavelength was 360 nm. Results It is a better timing to harvest when the flower is turning fruit and the leaf color is turning from green to yellow. Our results have demonstrated that at that time, the content of quercetin in Folium Apocyni Veneti was relatively higher. In addition, this report also shows that the concentration of quercetin in most medicinal materials from domestic market complies with the requirement of the Pharmacopoeia, but there were still a small percent of samples that didn't meet the Pharmacopoeia standards. Conclusion We suggested that the quality supervision and inspection on Folium Apocyni Veneti needs to be strengthened.
  • [1] 上海市食品药品监督管理局.上海市中药饮片炮制规范[S].上海:上海科技出版社,2008:245.
    [2] 张志琴,朱双雪.槲皮素的药理活性与临床应用研究进展[J].药学研究,2013,1(7):400-403.
    [3] 国家药典委员会.中华人民共和国药典2005年版一部[S].北京:化学工业出版社,2005:146-147.
    [4] 孟庆艳,马玲,吴增志,等. 不同采收期大花罗布麻叶中槲皮素的含量测定[J]. 塔里木大学学报,2010,22(3):22-24.
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Concentration measurement of the quercetin in Folium Apocyni Veneti from various commercial markets and harvest time

doi: 10.3969/j.issn.1006-0111.2017.01.016

Abstract: Objective To determine the quercetin content in Folium Apocyni Veneti from different commercial markets and harvest time by HPLC. Methods The determination was performed on an Aglient Eclipse XDB-C18 column (250 mm×4.6 mm,5 μm)at 30℃ with a mobile phase composed of Methanol:0.1% phosphoric acid run at gradient elution; the detection wavelength was 360 nm. Results It is a better timing to harvest when the flower is turning fruit and the leaf color is turning from green to yellow. Our results have demonstrated that at that time, the content of quercetin in Folium Apocyni Veneti was relatively higher. In addition, this report also shows that the concentration of quercetin in most medicinal materials from domestic market complies with the requirement of the Pharmacopoeia, but there were still a small percent of samples that didn't meet the Pharmacopoeia standards. Conclusion We suggested that the quality supervision and inspection on Folium Apocyni Veneti needs to be strengthened.

ZHANG Yihan, BIAN Yanfang. Concentration measurement of the quercetin in Folium Apocyni Veneti from various commercial markets and harvest time[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(1): 67-69. doi: 10.3969/j.issn.1006-0111.2017.01.016
Citation: ZHANG Yihan, BIAN Yanfang. Concentration measurement of the quercetin in Folium Apocyni Veneti from various commercial markets and harvest time[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(1): 67-69. doi: 10.3969/j.issn.1006-0111.2017.01.016
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