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XI Rong-gang, WANG Xiao-bo, LI Zhong-liang, YAO Wen, LI Jian. Studies on the dissolubility and liberation of aspirin enteric coatel tablet[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 83-85.
Citation:
LU Song-wei, SONG Hong-jie, CHEN Fang-jian. Simultaneous determination of phenol and camphor in compound camphor liniment by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(5): 347-349.
Simultaneous determination of phenol and camphor in compound camphor liniment by HPLC
Department of Pharmacy, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
Received Date: 2011-01-05
Rev Recd Date:
2011-04-08
Abstract
Objective To establish a method for simultaneous determination of phenol and camphor in compound camphor liniment by HPLC. Methods The separation was performed on a Kromasil C18 analytical column(150 mm×4.6 mm, 5 μm)with the mobile phase consisting of methanol-water(55:45).The detection wavelength was 287 nm.The flow rate was 0.8 ml/min. Results The standard curves were linear in the range of 103.4~827.2 μg/ml for phenol (r=0.999 1, n=5) and 205.1~1 640.8μg/ml(r=0.999 5, n=5)for camphor. The average recoveries of phenol and camphor were 99.61%(RSD=1.19%, n=9) and 99.83%(RSD=1.18%, n=9). Conclusion The method was simple and accurate with a good reproducibility, and could be used as a quality control method for compound camphor liniment.
Abstract: Objective To establish a method for simultaneous determination of phenol and camphor in compound camphor liniment by HPLC. Methods The separation was performed on a Kromasil C18 analytical column(150 mm×4.6 mm, 5 μm)with the mobile phase consisting of methanol-water(55:45).The detection wavelength was 287 nm.The flow rate was 0.8 ml/min. Results The standard curves were linear in the range of 103.4~827.2 μg/ml for phenol (r=0.999 1, n=5) and 205.1~1 640.8μg/ml(r=0.999 5, n=5)for camphor. The average recoveries of phenol and camphor were 99.61%(RSD=1.19%, n=9) and 99.83%(RSD=1.18%, n=9). Conclusion The method was simple and accurate with a good reproducibility, and could be used as a quality control method for compound camphor liniment.
XI Rong-gang, WANG Xiao-bo, LI Zhong-liang, YAO Wen, LI Jian. Studies on the dissolubility and liberation of aspirin enteric coatel tablet[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 83-85.
Citation:
LU Song-wei, SONG Hong-jie, CHEN Fang-jian. Simultaneous determination of phenol and camphor in compound camphor liniment by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(5): 347-349.
XI Rong-gang, WANG Xiao-bo, LI Zhong-liang, YAO Wen, LI Jian. Studies on the dissolubility and liberation of aspirin enteric coatel tablet[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 83-85.
XI Rong-gang, WANG Xiao-bo, LI Zhong-liang, YAO Wen, LI Jian. Studies on the dissolubility and liberation of aspirin enteric coatel tablet[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 83-85.
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