Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC

SUN Xue-xiong; LUO Chen-qu

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Volume 29 Issue 4

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2011 > 29(4): 278-280

SUN Xue-xiong, LUO Chen-qu. Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 278-280.

Citation:

SUN Xue-xiong, LUO Chen-qu. Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 278-280.

Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC

SUN Xue-xiong¹,
LUO Chen-qu²

1.
Department of Pharmacy, Loudi Center Hospital,Loudi 417000,China
2.
Loudi Institute for Drug control, Loudi 417000 China

Received Date: 2010-07-09
Rev Recd Date: 2011-03-04

Abstract

Objective To develop a HPLC method for determining the content of Chlorogenic acid in QingRexiaozhong Oral Liquid. Methods The phenomenex Luna-C₁₈(200 mm×4.60 mm ,5 μm)was used ;the mobile phase consisted of water-1%Acetic acid (20：80),the flow rate of 1.00 ml/min,and the detecting wavelength was 326 nm.The column temperature was at 30 ℃. Results There was a good linearity for Chlorogenic Acid in the range of 0.163 1~1.087 2 μg, r=1.000(n=5),and the average recovery rate was 100.40%, RSD=1.20%(n=9). Conclusions The method was simple,accurate,reliable and reproducible,which could be available for the quality control of QingRexiaozhong Oral Liquid
- Qingrexiaozhong oral liquid,
- Chlorogenic acid,
- HPLC,
- Content determination

References

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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