Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 28 Issue 1
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(1): 45-47

WANG Shu-dong, PAN Jing, FANG Li, XIA Shu-hui, SONG Bing-sheng. Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(1): 45-47.
Citation: WANG Shu-dong, PAN Jing, FANG Li, XIA Shu-hui, SONG Bing-sheng. Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(1): 45-47.
shu

Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC

  • Deptarment of Pharmaceuticals,Nanjing General Hospital of Nanjing Military Command,Nanjing 210002,China

  • Received Date: 2009-04-22
  • Rev Recd Date: 2009-10-16
  • Objective To establish a quantitative determination method for lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC. Methods The determination was carried out with a Hedera-ODS-3 C18 column(4.6 mm×250 mm,5 μm).The mobile phase consisted of acetonitrile-1%phosphoric acid solution(12:88),with pH adjusted to 3.0±0.1 by using triethylamine.Detecting wavelength was at 254 nm. Results The linear range for lidocaine hydrochloride and norfloxacine was both 0.025～0.100 mg/ml.The average recovery and RSD of norfloxacine were 98.84% and 1.72%,and those of lidocaine hydrochloride were 100.24% and 1.86%. Conclusion The method offers simple instrumental operation,good stability,and high accuracy for the determination of the chitosan hemostatic sponge.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2720) PDF downloads(624) Cited by()

Related
Proportional views

Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC

  • Deptarment of Pharmaceuticals,Nanjing General Hospital of Nanjing Military Command,Nanjing 210002,China
  • Received Date: 2009-04-22
  • Rev Recd Date: 2009-10-16

Abstract: Objective To establish a quantitative determination method for lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC. Methods The determination was carried out with a Hedera-ODS-3 C18 column(4.6 mm×250 mm,5 μm).The mobile phase consisted of acetonitrile-1%phosphoric acid solution(12:88),with pH adjusted to 3.0±0.1 by using triethylamine.Detecting wavelength was at 254 nm. Results The linear range for lidocaine hydrochloride and norfloxacine was both 0.025～0.100 mg/ml.The average recovery and RSD of norfloxacine were 98.84% and 1.72%,and those of lidocaine hydrochloride were 100.24% and 1.86%. Conclusion The method offers simple instrumental operation,good stability,and high accuracy for the determination of the chitosan hemostatic sponge.

WANG Shu-dong, PAN Jing, FANG Li, XIA Shu-hui, SONG Bing-sheng. Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(1): 45-47.
Citation: WANG Shu-dong, PAN Jing, FANG Li, XIA Shu-hui, SONG Bing-sheng. Determination of lidocaine hydrochloride and norfloxacine in chitosan hemostatic sponge by RP-HPLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(1): 45-47.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return