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Volume 26 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (2): 145-146,153

ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
Citation: ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
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Study on stability of valproic acid and carbamazepine concentrations in serum samples

  • Department of Pharmacy & Pharmacology,First Hospital Affiliated to PLA General Hospital,Beijing 100037,China

  • Received Date: 2007-03-06
  • Objective: To investigate the effects on serum drug concentrations of valproic acid and carbamazepine with different storage requirements of serum sample. Methods: Methods The serum samples from epileptic patients were stored at normal temperature(23 ℃±2 ℃)for 7 days and 14 days or in refrigerator(5 ℃±1 ℃) for 7 days.Then these samples were determined by FPIA and the results were compared with the new ones. Results: Compared with the new samples,the samples which were stored for 7 or 14 days were no significant differences. Conclusion: Serum samples of valproic acid and carbamazepine can be stored stably at normal temperature for 14 days.
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Study on stability of valproic acid and carbamazepine concentrations in serum samples

  • Department of Pharmacy & Pharmacology,First Hospital Affiliated to PLA General Hospital,Beijing 100037,China
  • Received Date: 2007-03-06

Abstract: Objective: To investigate the effects on serum drug concentrations of valproic acid and carbamazepine with different storage requirements of serum sample. Methods: Methods The serum samples from epileptic patients were stored at normal temperature(23 ℃±2 ℃)for 7 days and 14 days or in refrigerator(5 ℃±1 ℃) for 7 days.Then these samples were determined by FPIA and the results were compared with the new ones. Results: Compared with the new samples,the samples which were stored for 7 or 14 days were no significant differences. Conclusion: Serum samples of valproic acid and carbamazepine can be stored stably at normal temperature for 14 days.

ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
Citation: ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
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