Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review, editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!
ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
Citation:
ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
Study on stability of valproic acid and carbamazepine concentrations in serum samples
Department of Pharmacy & Pharmacology,First Hospital Affiliated to PLA General Hospital,Beijing 100037,China
Received Date: 2007-03-06
Abstract
Objective: To investigate the effects on serum drug concentrations of valproic acid and carbamazepine with different storage requirements of serum sample. Methods: Methods The serum samples from epileptic patients were stored at normal temperature(23 ℃±2 ℃)for 7 days and 14 days or in refrigerator(5 ℃±1 ℃) for 7 days.Then these samples were determined by FPIA and the results were compared with the new ones. Results: Compared with the new samples,the samples which were stored for 7 or 14 days were no significant differences. Conclusion: Serum samples of valproic acid and carbamazepine can be stored stably at normal temperature for 14 days.
Abstract: Objective: To investigate the effects on serum drug concentrations of valproic acid and carbamazepine with different storage requirements of serum sample. Methods: Methods The serum samples from epileptic patients were stored at normal temperature(23 ℃±2 ℃)for 7 days and 14 days or in refrigerator(5 ℃±1 ℃) for 7 days.Then these samples were determined by FPIA and the results were compared with the new ones. Results: Compared with the new samples,the samples which were stored for 7 or 14 days were no significant differences. Conclusion: Serum samples of valproic acid and carbamazepine can be stored stably at normal temperature for 14 days.
ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
Citation:
ZHOU Liang, WANG Ming-Mei, MA Jian-Li. Study on stability of valproic acid and carbamazepine concentrations in serum samples[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 145-146,153.
DownLoad: