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Volume 26 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (2): 133-135

GAO Jin, FU Cong, JI Yang, NIE Yu-Qiong, HU Dan. Application of bacterial endotoxin test to compound pralidoxime chloride injection[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 133-135.
Citation: GAO Jin, FU Cong, JI Yang, NIE Yu-Qiong, HU Dan. Application of bacterial endotoxin test to compound pralidoxime chloride injection[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 133-135.
shu

Application of bacterial endotoxin test to compound pralidoxime chloride injection

  • 1.

    Institute for Drug and Instrument Control of Health Dept GLD of PLA,Beijing 100071,China

  • 2.

    Department of Pharmacy,307 Hospital of PLA,Beijing 100039,China

  • Received Date: 2007-09-01
  • Objective: To establish an application of bacterial endotoxin test to compound pralidoxime chloride injection. Methods: The expriment was carried out based on the bacterial endotoxin test in Chinese pharmacopoeia 2005 edition. Results: It was proved that the maximum noninterference concentration of compound pralidoxime chloride injection was pralidoxime chloride 10 mg/mL and the sensitivity of TAL was 0.25 EU/mL. Conclusion: The results suggested that the bacterial endotoxin test was suitable for the detection of endotoxin in compound pralidoxime chloride injection and the bacterial endotoxin limit was 0.2 EU/mg.
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Application of bacterial endotoxin test to compound pralidoxime chloride injection

  • 1. Institute for Drug and Instrument Control of Health Dept GLD of PLA,Beijing 100071,China
  • 2. Department of Pharmacy,307 Hospital of PLA,Beijing 100039,China
  • Received Date: 2007-09-01

Abstract: Objective: To establish an application of bacterial endotoxin test to compound pralidoxime chloride injection. Methods: The expriment was carried out based on the bacterial endotoxin test in Chinese pharmacopoeia 2005 edition. Results: It was proved that the maximum noninterference concentration of compound pralidoxime chloride injection was pralidoxime chloride 10 mg/mL and the sensitivity of TAL was 0.25 EU/mL. Conclusion: The results suggested that the bacterial endotoxin test was suitable for the detection of endotoxin in compound pralidoxime chloride injection and the bacterial endotoxin limit was 0.2 EU/mg.

GAO Jin, FU Cong, JI Yang, NIE Yu-Qiong, HU Dan. Application of bacterial endotoxin test to compound pralidoxime chloride injection[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 133-135.
Citation: GAO Jin, FU Cong, JI Yang, NIE Yu-Qiong, HU Dan. Application of bacterial endotoxin test to compound pralidoxime chloride injection[J]. Journal of Pharmaceutical Practice and Service, 2008, (2): 133-135.
shu

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