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Volume 24 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2006  >  (6): 339-341,356

GONG Chun-gui, ZHANG Guo-qing, WANG Xi-ying, LEI Yan-hui. Experimental studies of anti-inflammatory and analgesic effects of extract from Herba agrimoniae[J]. Journal of Pharmaceutical Practice and Service, 2006, (6): 339-341,356.
Citation: GONG Chun-gui, ZHANG Guo-qing, WANG Xi-ying, LEI Yan-hui. Experimental studies of anti-inflammatory and analgesic effects of extract from Herba agrimoniae[J]. Journal of Pharmaceutical Practice and Service, 2006, (6): 339-341,356.
shu

Experimental studies of anti-inflammatory and analgesic effects of extract from Herba agrimoniae

  • Department of Pharmacy,Eastern Hospital of Hepatobiliary Surgery,Second Military Medical University,Shanghai 200438,China

  • Received Date: 2006-06-29
  • Objective: To investigate the anti-inflammatory and analgesic effects of extract of Herba agrimoniae. Methods: The anti- inflammatory and analgesic effects of alcohol extract and water extract from Herba agrimoniae were observed by means of acetic acid in- ducing mouse writhing model,hot plate method,dimethylbenzene inducing ear edema model and carrageenan inducing rat voix pedis swell model. Results: It was found that alcohol extract and water extract from Herba agrimoniae markedly reducing the writhing fre- quency induced by acetic acid,significantly increasing the pain threshold in mice induced by hot plate,evidently suppressing the mouse's ear edema induced by dimethylbenzene and significantly mitigating the rat voix pedis swell inducing by carrageenan.The action of alcohol extract was better than which of water extract. Conclusion: The alcohol extract from Herba agrimoniae has notable effects on anti-inflammation and analgesia.
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Experimental studies of anti-inflammatory and analgesic effects of extract from Herba agrimoniae

  • Department of Pharmacy,Eastern Hospital of Hepatobiliary Surgery,Second Military Medical University,Shanghai 200438,China
  • Received Date: 2006-06-29

Abstract: Objective: To investigate the anti-inflammatory and analgesic effects of extract of Herba agrimoniae. Methods: The anti- inflammatory and analgesic effects of alcohol extract and water extract from Herba agrimoniae were observed by means of acetic acid in- ducing mouse writhing model,hot plate method,dimethylbenzene inducing ear edema model and carrageenan inducing rat voix pedis swell model. Results: It was found that alcohol extract and water extract from Herba agrimoniae markedly reducing the writhing fre- quency induced by acetic acid,significantly increasing the pain threshold in mice induced by hot plate,evidently suppressing the mouse's ear edema induced by dimethylbenzene and significantly mitigating the rat voix pedis swell inducing by carrageenan.The action of alcohol extract was better than which of water extract. Conclusion: The alcohol extract from Herba agrimoniae has notable effects on anti-inflammation and analgesia.

GONG Chun-gui, ZHANG Guo-qing, WANG Xi-ying, LEI Yan-hui. Experimental studies of anti-inflammatory and analgesic effects of extract from Herba agrimoniae[J]. Journal of Pharmaceutical Practice and Service, 2006, (6): 339-341,356.
Citation: GONG Chun-gui, ZHANG Guo-qing, WANG Xi-ying, LEI Yan-hui. Experimental studies of anti-inflammatory and analgesic effects of extract from Herba agrimoniae[J]. Journal of Pharmaceutical Practice and Service, 2006, (6): 339-341,356.
shu

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