The improve of the method for determination compound fluocinonide ointment

YANG Xi-Xiang; GU Li

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Volume 20 Issue 3

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2002 > (3): 171-173

YANG Xi-Xiang, GU Li. The improve of the method for determination compound fluocinonide ointment[J]. Journal of Pharmaceutical Practice and Service, 2002, (3): 171-173.

Citation:

YANG Xi-Xiang, GU Li. The improve of the method for determination compound fluocinonide ointment[J]. Journal of Pharmaceutical Practice and Service, 2002, (3): 171-173.

The improve of the method for determination compound fluocinonide ointment

Huainan Institute for Drug Control, Huainan 232007, China;
2. The 534th Hospital of PLA, Luoyang 471003, China

Received Date: 2002-01-15

Abstract

OBJECTIVE To improve the method for determination compound fluocinonide ointment.METHODS A method of RP HPLC be used, plus the internal standard after extraction and filter.ODS column (250mm×4.6mm, 5μm) was selected and the mobile phase was consisted of methanol-water-ether(62:38:2,v/v/v) at flow rate of 1.0ml·min^-1.The detection wavelength was 240nm.RESULTS The precision and the accuracy of improved method are good.CONCLUSION The problem of the old method was solved with this improved method and have a universal significance for the determination of ointment preparation.
- compound fluocinonide,
- RP-HPLC,
- ointment
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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