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Volume 20 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2002  >  (1): 17-18

MU Bing, XU Gui-li, PENG Xian-ping, YANG Yan, FANG Li-sha. Study on mutual action of granisetron with pharmorubicin,doxorubicin[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 17-18.
Citation: MU Bing, XU Gui-li, PENG Xian-ping, YANG Yan, FANG Li-sha. Study on mutual action of granisetron with pharmorubicin,doxorubicin[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 17-18.
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Study on mutual action of granisetron with pharmorubicin,doxorubicin

  • 1.

    Pharmacy of Kunming General Hospital of Chengdu Military Region, Kunming 650032, China

  • 2.

  • 3.

  • Received Date: 2001-05-14
  • OBJECTIVE To study the compatible stability of granisetron with two kinds of anticancer drugs(pharmorubicin,doxorubicin)in 0.9% NaCl solution.METHODS Absorption ratioes of compatible content of granisetron with pharmorubicin,doxorubicin were investigatal by ultrariolet spectrophotometry,and the pH,new substemces formed were determined by TLC.RESULTS There were no evident changes in appearance,pH and spectrum at room temperature 25℃ within 0～8 hours. There was no new substances formed by TLC.CONCLUSION Granisetron with pharmorubicin,doxorubicin in 0.9%NaCl can be used.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Study on mutual action of granisetron with pharmorubicin,doxorubicin

  • 1. Pharmacy of Kunming General Hospital of Chengdu Military Region, Kunming 650032, China
  • 2. 
  • 3. 
  • Received Date: 2001-05-14

Abstract: OBJECTIVE To study the compatible stability of granisetron with two kinds of anticancer drugs(pharmorubicin,doxorubicin)in 0.9% NaCl solution.METHODS Absorption ratioes of compatible content of granisetron with pharmorubicin,doxorubicin were investigatal by ultrariolet spectrophotometry,and the pH,new substemces formed were determined by TLC.RESULTS There were no evident changes in appearance,pH and spectrum at room temperature 25℃ within 0～8 hours. There was no new substances formed by TLC.CONCLUSION Granisetron with pharmorubicin,doxorubicin in 0.9%NaCl can be used.

MU Bing, XU Gui-li, PENG Xian-ping, YANG Yan, FANG Li-sha. Study on mutual action of granisetron with pharmorubicin,doxorubicin[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 17-18.
Citation: MU Bing, XU Gui-li, PENG Xian-ping, YANG Yan, FANG Li-sha. Study on mutual action of granisetron with pharmorubicin,doxorubicin[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 17-18.
shu

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