Pharmacokineties of Vitamin E microcapsules in rabbits

Feng Lin; Fu Junpeng; WangBo; Wang Jingxiang

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Volume 16 Issue 4

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Article Navigation > Journal of Pharmaceutical Practice and Service > 1998 > (4): 193-195

Feng Lin, Fu Junpeng, WangBo, Wang Jingxiang. Pharmacokineties of Vitamin E microcapsules in rabbits[J]. Journal of Pharmaceutical Practice and Service, 1998, (4): 193-195.

Citation:

Feng Lin, Fu Junpeng, WangBo, Wang Jingxiang. Pharmacokineties of Vitamin E microcapsules in rabbits[J]. Journal of Pharmaceutical Practice and Service, 1998, (4): 193-195.

Pharmacokineties of Vitamin E microcapsules in rabbits

General Hospital of Jinan Command, Jinan 250031

Abstract

The pharmacokineties of vitamine E microcapsules were studied. Concentration of plasma was determined by UV after ig 100mg/kg Vitamin E of vitamin E microcapsules being given rabbits.The pharmacokineties of vitamin E fitted to a two-compartment medal with lag time using PKBP-N1 program. The results of vitamin E microcapsules is: t_1/2Ka=3. 246±1.667h, t_1/2α=7.150±1.899, t_1/2β=38.305±13.34h, C_max=8.625±2.404mg/L;T_max=12. 10±3.807;AUC_0～∞=298.36±80.20h·mg/L.
- vitamin E microcapsules,
- pharmacokineties
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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