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HUANG Wei, YU Juan, DENG XiaoLi, WANG LiQin, SUN Qiang. Study on the application of epinephrine hydrochloride in senile ptosis surgery[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 180-182. doi: 10.3969/j.issn.1006-0111.2018.02.018
Citation: HUANG Wei, YU Juan, DENG XiaoLi, WANG LiQin, SUN Qiang. Study on the application of epinephrine hydrochloride in senile ptosis surgery[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 180-182. doi: 10.3969/j.issn.1006-0111.2018.02.018

Study on the application of epinephrine hydrochloride in senile ptosis surgery

doi: 10.3969/j.issn.1006-0111.2018.02.018
  • Received Date: 2017-01-24
  • Rev Recd Date: 2017-12-05
  • Objective To explore the application of mixed anesthesia with epinephrine hydrochloride and lidocaine in senile ptosis surgery. Methods 90 senile ptosis cases (180 eyes) treated from January 2016 to June 2016 were randomly divided into experimental group and control group. Subcutaneous infiltration anesthesia with lidocaine and epinephrine hydrochloride was used in the experimental group, while the control group received lidocaine only. The heart rate, blood pressure, blood loss, visual field definition, operation time, incision state, cornea and recovery rate of the two groups were observed. Results ① The systolic blood pressure of the patients in the experimental group was significantly higher than that of the control group (P<0.05). There was no significant difference between two groups in diastolic blood pressure and heart rate (P>0.05). ② The experimental group achieved better results than the control group in operation time, anesthesia time, amount of bleeding, visual field clarity, eyelid congestion and wound healing (P<0.05); ③ There was no significant difference (P> 0.05) between two groups in incisional dressing bleeding, fluid seepage and cornea status. Conclusion The mixed anesthesia of epinephrine hydrochloride and lidocaine had little effect on the patients' diastolic blood pressure and heart rate. It reduced the blood loss during operation and the postoperative eyelid congestion. The clarity of intraoperative vision and recovery time were also improved with the mixed anesthesia.
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Study on the application of epinephrine hydrochloride in senile ptosis surgery

doi: 10.3969/j.issn.1006-0111.2018.02.018

Abstract: Objective To explore the application of mixed anesthesia with epinephrine hydrochloride and lidocaine in senile ptosis surgery. Methods 90 senile ptosis cases (180 eyes) treated from January 2016 to June 2016 were randomly divided into experimental group and control group. Subcutaneous infiltration anesthesia with lidocaine and epinephrine hydrochloride was used in the experimental group, while the control group received lidocaine only. The heart rate, blood pressure, blood loss, visual field definition, operation time, incision state, cornea and recovery rate of the two groups were observed. Results ① The systolic blood pressure of the patients in the experimental group was significantly higher than that of the control group (P<0.05). There was no significant difference between two groups in diastolic blood pressure and heart rate (P>0.05). ② The experimental group achieved better results than the control group in operation time, anesthesia time, amount of bleeding, visual field clarity, eyelid congestion and wound healing (P<0.05); ③ There was no significant difference (P> 0.05) between two groups in incisional dressing bleeding, fluid seepage and cornea status. Conclusion The mixed anesthesia of epinephrine hydrochloride and lidocaine had little effect on the patients' diastolic blood pressure and heart rate. It reduced the blood loss during operation and the postoperative eyelid congestion. The clarity of intraoperative vision and recovery time were also improved with the mixed anesthesia.

HUANG Wei, YU Juan, DENG XiaoLi, WANG LiQin, SUN Qiang. Study on the application of epinephrine hydrochloride in senile ptosis surgery[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 180-182. doi: 10.3969/j.issn.1006-0111.2018.02.018
Citation: HUANG Wei, YU Juan, DENG XiaoLi, WANG LiQin, SUN Qiang. Study on the application of epinephrine hydrochloride in senile ptosis surgery[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(2): 180-182. doi: 10.3969/j.issn.1006-0111.2018.02.018
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