Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

WU Yue, WANG Aihua, HAN Chaohong, FENG Xin. A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 552-555. doi: 10.3969/j.issn.1006-0111.2016.06.017
Citation: WU Yue, WANG Aihua, HAN Chaohong, FENG Xin. A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 552-555. doi: 10.3969/j.issn.1006-0111.2016.06.017

A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy

doi: 10.3969/j.issn.1006-0111.2016.06.017
  • Received Date: 2016-05-04
  • Rev Recd Date: 2016-09-01
  • Objective To study the conservative treatment for cesarean scar pregnancy (CSP) with proper medications. Methods One case of CSP with uterine apoplexy was reported. Medication regimens were illustrated as the conservative treatments for the patient with β-HCG>20 000 IU/L, in whom surgery was contraindicated. Results After two times of uterine artery embolization and chemotherapy (MTX50 mg), followed by three times of MTX50 mg cervical injection combined with oral mifepristone, serum β-HCG dropped to normal level and no adverse reactions were observed. Conclusion Clinical pharmacists could strengthen the safety and effectiveness of rational drug use by participating in the integrated pharmacy care.
  • [1] 中华医学会计划生育学分会. 剖宫产瘢痕妊娠诊断与治疗共识[J]. 中华医学杂志, 2012, 92(25):1731-1733.
    [2] 施腾飞, 童晓文. 剖宫产瘢痕妊娠的诊断与治疗进展[J]. 国际妇产科学杂志, 2014, 41(1):10-13
    [3] 李瑾瑾, 刘欣燕. 剖宫产瘢痕妊娠的治疗选择[J].中国医学科学院学报, 2014, 36(2):209-213.
    [4] 陈国强, 谢春明. 子宫动脉栓塞/化疗栓塞术在治疗剖宫产后子宫切口妊娠中的应用价值[J]. 当代医学, 2009, 15(17):325-327.
    [5] Zhang B, Jiang ZB, Huang MS,et al.Uterine arteryembolization combined with methotrexate in the treatment of cesarean scar pregnancy:results of a case series and review of the literature[J]. J Vasc Interv Radiol, 2012, 23(12):1582-1588.
    [6] Gómez García MT, Aguarón Benitez G, Barberá Belda B,et al. Medical therapy (methotrexate and mifepristone) alone or in combination with another type of therapy for the management of cervical or interstitial ectopic pregnancy[J]. Eur J Obstet Gynecol Reprod Biol, 2012, 165(1):77-81.
    [7] Kalampokas E, Boutas I, Panoulis K, et al. Novel medical therapy of cesarean scar pregnancy with a viable embryo combining multidose methotrexate and mifepristone:a case report[J]. Medicine (Baltimore), 2015,94(41):e1697.
    [8] Garbin O, de Tayrac R, de Poncheville L,et al. Medical treatment of ectopic pregnancy:a randomized clinical trial comparing metotrexate-mifepristone and methotrexate-placebo[J]. J Gynecol Obstet Biol Reprod (Paris), 2004,33(5):391-400.
    [9] 罗丹, 钟玲, 赵腾飞. 甲氨蝶呤联合米非司酮与单用甲氨蝶呤治疗异位妊娠的疗效评价[J].解放军医学杂志, 2011, 36(2):184-187.
    [10] 裴海英,张大微,吴钦兰, 等. 甲氨蝶呤联合宫外孕Ⅱ号方与米非司酮治疗异位妊娠的随机对照试验[J]. 中国循证医学杂志, 2012, 12(2):168-172.
    [11] 李景会, 刘聪慧, 夏凤艳. 3种方案治疗异位妊娠的疗效及成本-效果分析[J]. 现代预防医学, 2013, 40(11):2044-2048.
    [12] 张淑贤. 不同剂量米非司酮治疗异位妊娠的临床观察[J]. 实用妇产科杂志, 2006,22(4):210-212.
    [13] 龚寅芸. 不同剂量米非司酮联合甲氨蝶呤治疗异位妊娠疗效观察[J]. 中国医药导报, 2010,7(32):60-61.
    [14] 陈新磊, 张君娜. 甲氨蝶呤、米非司酮及两者联用保守治疗异位妊娠的临床观察[J]. 中国妇幼保健, 2011,26(2):297-298.
    [15] 刘馨, 张丽. 氨甲蝶呤联合米非司酮不同给药方案治疗异位妊娠疗效观察[J]. 中国妇幼保健, 2007,22(27):3909-3910.
    [16] Shrestha E, Yang Y, Li X, et al. Successful conservative management with methotrexate and mifepristone of cervical pregnancy[J]. J Biomed Res, 2011, 25(1):71-73.
    [17] 任月月, 劳利迪.甲氨蝶呤联合米非司酮治疗异位妊娠的疗效及不良反应观察[J]. 中国基层医药, 2014,21(18):2868-2869.
    [18] 陈青文, 吴学明, 陈燕娥. 氨甲蝶呤宫颈注射与肌肉注射治疗异位妊娠疗效分析[J].中国妇幼保健, 2009, 24(13):1865-1866.
    [19] 孙海艳, 尹珊珊. 宫颈注射与全身用药应用甲氨蝶呤治疗异位妊娠疗效对比[J]微量元素与健康研究, 2015, 32(1):17-18.
    [20] 邓新粮, 何小丽, 肖松舒. 剖宫产术后子宫切口部位妊娠保守治疗16例疗效分析[J]. 实用妇产科杂志, 2008, 24(6):372-373.
    [21] 马静, 苑学, 蒋利东, 等. 宫颈注射甲氨蝶呤保守治疗宫外孕临床观察[J]. 河北医药, 2010, 32(23):3295-3296.
    [22] 左文莉. 提高剖宫产瘢痕妊娠的诊治水平,降低妇女的生殖危害——对《剖宫产瘢痕妊娠诊断与治疗共识》的解读[J]. 中国医学杂志, 2012, 92(25):1729-1730.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(2618) PDF downloads(334) Cited by()

Related
Proportional views

A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy

doi: 10.3969/j.issn.1006-0111.2016.06.017

Abstract: Objective To study the conservative treatment for cesarean scar pregnancy (CSP) with proper medications. Methods One case of CSP with uterine apoplexy was reported. Medication regimens were illustrated as the conservative treatments for the patient with β-HCG>20 000 IU/L, in whom surgery was contraindicated. Results After two times of uterine artery embolization and chemotherapy (MTX50 mg), followed by three times of MTX50 mg cervical injection combined with oral mifepristone, serum β-HCG dropped to normal level and no adverse reactions were observed. Conclusion Clinical pharmacists could strengthen the safety and effectiveness of rational drug use by participating in the integrated pharmacy care.

WU Yue, WANG Aihua, HAN Chaohong, FENG Xin. A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 552-555. doi: 10.3969/j.issn.1006-0111.2016.06.017
Citation: WU Yue, WANG Aihua, HAN Chaohong, FENG Xin. A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 552-555. doi: 10.3969/j.issn.1006-0111.2016.06.017
Reference (22)

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return