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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2016  >  34(6): 526-529

LIANG Ruishu, XIONG Liyan, LI Ling, ZHANG Chuan. Analysis of liposoluble chemicals from Achillea Alpina L. by GC-MS[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 526-529. doi: 10.3969/j.issn.1006-0111.2016.06.011
Citation: LIANG Ruishu, XIONG Liyan, LI Ling, ZHANG Chuan. Analysis of liposoluble chemicals from Achillea Alpina L. by GC-MS[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 526-529. doi: 10.3969/j.issn.1006-0111.2016.06.011
shu

Analysis of liposoluble chemicals from Achillea Alpina L. by GC-MS

doi: 10.3969/j.issn.1006-0111.2016.06.011

  • School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2016-03-31
  • Rev Recd Date: 2016-07-20
  • Objective To identify the chemical structures for the components in the liposoluble portion of Achillea alpina L. by gas chromatography/mass spectrometry (GC-MS). Methods Achillea alpina L. was extracted with 95% alcohol and petroleum ether. The chemical compositions in the extract were analyzed with GC-MS. The structures were identified by comparing to the authentic samples and searching NIST 10 database. The relative content of each compound in the extract was calculated by area normalization method. Results Twenty-nine compounds were separated and identified, which accounted for 82.74% of petroleum ether extract. The major constituents were octamethylpicen-3-ol (33.16%), Lup20(29)-en-3-ol,acetate(3b)(10.99%), n-Hexadecanoic acid(7.98%), Stigmasterol(3.68%), Octadecanoic acid(3.55%), Friedelan-3-one (3.51%). Conclusion This simple and accurate method can be used for the assay of liposoluble chemicals from Achillea alpina L. The results provide a foundation for pharmacological research and better use the resource of Achillea alpina L.
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Analysis of liposoluble chemicals from Achillea Alpina L. by GC-MS

doi: 10.3969/j.issn.1006-0111.2016.06.011
  • School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2016-03-31
  • Rev Recd Date: 2016-07-20

Abstract: Objective To identify the chemical structures for the components in the liposoluble portion of Achillea alpina L. by gas chromatography/mass spectrometry (GC-MS). Methods Achillea alpina L. was extracted with 95% alcohol and petroleum ether. The chemical compositions in the extract were analyzed with GC-MS. The structures were identified by comparing to the authentic samples and searching NIST 10 database. The relative content of each compound in the extract was calculated by area normalization method. Results Twenty-nine compounds were separated and identified, which accounted for 82.74% of petroleum ether extract. The major constituents were octamethylpicen-3-ol (33.16%), Lup20(29)-en-3-ol,acetate(3b)(10.99%), n-Hexadecanoic acid(7.98%), Stigmasterol(3.68%), Octadecanoic acid(3.55%), Friedelan-3-one (3.51%). Conclusion This simple and accurate method can be used for the assay of liposoluble chemicals from Achillea alpina L. The results provide a foundation for pharmacological research and better use the resource of Achillea alpina L.

LIANG Ruishu, XIONG Liyan, LI Ling, ZHANG Chuan. Analysis of liposoluble chemicals from Achillea Alpina L. by GC-MS[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 526-529. doi: 10.3969/j.issn.1006-0111.2016.06.011
Citation: LIANG Ruishu, XIONG Liyan, LI Ling, ZHANG Chuan. Analysis of liposoluble chemicals from Achillea Alpina L. by GC-MS[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 526-529. doi: 10.3969/j.issn.1006-0111.2016.06.011
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