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Volume 30 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(4): 275-278

WU Jian-lin, WANG Ping, GAO Peng, ZENG Na, LIU Xiang-fang, WANG Sui-yi, SHEN Yang, XU Chao-dou. Studies on the chemical constituents in leaves of Rosa Laevigata Michx[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 275-278.
Citation: WU Jian-lin, WANG Ping, GAO Peng, ZENG Na, LIU Xiang-fang, WANG Sui-yi, SHEN Yang, XU Chao-dou. Studies on the chemical constituents in leaves of Rosa Laevigata Michx[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 275-278.
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Studies on the chemical constituents in leaves of Rosa Laevigata Michx

  • 1.

    Shandong University of Traditional Chinese Medicine, Jinan 250355, China

  • 2.

    Beijing Tongrentang Herbal Medicine Company, Beijing 100035, China

  • 3.

    Shanghai Children′s Hospital, Shanghai 200040, China

  • 4.

    Institute For Drug and Instrument Control of PLA, Beijing 100071

  • Received Date: 2012-03-15
  • Rev Recd Date: 2012-06-10
  • Objective To investigate the chemical constituents from leaves of Rosa Laevigata Michx.Methods The chemical constituents were isolated and purifieated by silica gel column chromatography,Sephadex LH-20 and semi-preparative RP-HPLC. Their structures were identified by spectral data together with physicochemical analysis,Results Twelve known compounds were isolated and identified as catechin(1),quercetin(2),naringenin(3),kaempferol(4),ethyl gallate(5),p-hydroxyl ethyl cinnamate(6),ω-hydroxypropioquaiacone(7),hydroxytyrosol(8),o-hydraxybeuzoic acid(9),scopoletin(10),ethyl α-D-arabillofuranoside(11),methyl β-D-glucopyranoside(12).Conclusion Compound 11 was isolated from genus Rosa for the first time,compounds 3,5-9 were isolated from leaves of Rosa Laevigata Michx for the first time.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Studies on the chemical constituents in leaves of Rosa Laevigata Michx

  • 1. Shandong University of Traditional Chinese Medicine, Jinan 250355, China
  • 2. Beijing Tongrentang Herbal Medicine Company, Beijing 100035, China
  • 3. Shanghai Children′s Hospital, Shanghai 200040, China
  • 4. Institute For Drug and Instrument Control of PLA, Beijing 100071
  • Received Date: 2012-03-15
  • Rev Recd Date: 2012-06-10

Abstract: Objective To investigate the chemical constituents from leaves of Rosa Laevigata Michx.Methods The chemical constituents were isolated and purifieated by silica gel column chromatography,Sephadex LH-20 and semi-preparative RP-HPLC. Their structures were identified by spectral data together with physicochemical analysis,Results Twelve known compounds were isolated and identified as catechin(1),quercetin(2),naringenin(3),kaempferol(4),ethyl gallate(5),p-hydroxyl ethyl cinnamate(6),ω-hydroxypropioquaiacone(7),hydroxytyrosol(8),o-hydraxybeuzoic acid(9),scopoletin(10),ethyl α-D-arabillofuranoside(11),methyl β-D-glucopyranoside(12).Conclusion Compound 11 was isolated from genus Rosa for the first time,compounds 3,5-9 were isolated from leaves of Rosa Laevigata Michx for the first time.

WU Jian-lin, WANG Ping, GAO Peng, ZENG Na, LIU Xiang-fang, WANG Sui-yi, SHEN Yang, XU Chao-dou. Studies on the chemical constituents in leaves of Rosa Laevigata Michx[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 275-278.
Citation: WU Jian-lin, WANG Ping, GAO Peng, ZENG Na, LIU Xiang-fang, WANG Sui-yi, SHEN Yang, XU Chao-dou. Studies on the chemical constituents in leaves of Rosa Laevigata Michx[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(4): 275-278.
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