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Volume 28 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(6): 451-455

ZHANG Qi, XIA Ai-jun. Meta-analysis of combining rh-endostatin with chemotherapy in treatment of NSCLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 451-455.
Citation: ZHANG Qi, XIA Ai-jun. Meta-analysis of combining rh-endostatin with chemotherapy in treatment of NSCLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 451-455.
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Meta-analysis of combining rh-endostatin with chemotherapy in treatment of NSCLC

  • Department of pharmacy,303 hospital of PLA,Nanning 530021,China

  • Received Date: 2010-04-02
  • Rev Recd Date: 2010-04-02
  • Objective To evaluate the efficacy of combining rh-endostatin with chemotherapy for non-small cell lung cancer(NSCLC) compared with chemotherapy alone. Methods The literature of randomized clinical trials(RCTs) that compared the efficacy of combining rh-endostatin with chemotherapy and chemotherapy alone form 2000 to 2009 were collected.Meta-analysis was employed to evaluate the Results of these therapies by RevMan 4.2.11 literature was seclected including 915 cases. Results Compared with control group,the total OR of efficiency rate of combining rh-endostatin with chemotherapy was 2.49,(95%CI,1.83-3.40),OR of the disease control rate were 1.91,(95%CI,1.40-2.59),both showing significant difference(P<0.01). Conclusion Combining rh-endostatin with chemotherapy was superior to chemotherapy alone in treatment of NSCLC in total efficiency rate and disease control rate.
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Meta-analysis of combining rh-endostatin with chemotherapy in treatment of NSCLC

  • Department of pharmacy,303 hospital of PLA,Nanning 530021,China
  • Received Date: 2010-04-02
  • Rev Recd Date: 2010-04-02

Abstract: Objective To evaluate the efficacy of combining rh-endostatin with chemotherapy for non-small cell lung cancer(NSCLC) compared with chemotherapy alone. Methods The literature of randomized clinical trials(RCTs) that compared the efficacy of combining rh-endostatin with chemotherapy and chemotherapy alone form 2000 to 2009 were collected.Meta-analysis was employed to evaluate the Results of these therapies by RevMan 4.2.11 literature was seclected including 915 cases. Results Compared with control group,the total OR of efficiency rate of combining rh-endostatin with chemotherapy was 2.49,(95%CI,1.83-3.40),OR of the disease control rate were 1.91,(95%CI,1.40-2.59),both showing significant difference(P<0.01). Conclusion Combining rh-endostatin with chemotherapy was superior to chemotherapy alone in treatment of NSCLC in total efficiency rate and disease control rate.

ZHANG Qi, XIA Ai-jun. Meta-analysis of combining rh-endostatin with chemotherapy in treatment of NSCLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 451-455.
Citation: ZHANG Qi, XIA Ai-jun. Meta-analysis of combining rh-endostatin with chemotherapy in treatment of NSCLC[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(6): 451-455.
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