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DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.
Citation: DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.

Orthogonal design of formula optimization for Huanggui enema

  • Received Date: 2009-11-04
  • Rev Recd Date: 2010-01-22
  • Objective To choose the best formula for Huanggui enema. Methods The orthogonal test was used to optimize formula,and the clearance index in mice and antibacterial action in vitro were observation index.The best formula was designed according to the result of this study. Results The formula is: Rhizoma Coptids 60 g,Cortex phellodendn 180 g,Ramulus Cinnamoni 120 g,Radixet Rhizoma Rhei 48 g per 1 000 ml.The clearance index in mice is greater 20%,diameter of inhibition zone is greater 35 mm. Conclusion The optimized formula is reasonable and provided an experimental basis for clinical application.
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    Created with Highcharts 5.0.7Chart context menuAccess Class DistributionFULLTEXT: 84.4 %FULLTEXT: 84.4 %META: 7.9 %META: 7.9 %PDF: 7.7 %PDF: 7.7 %FULLTEXTMETAPDFHighcharts.com
    Created with Highcharts 5.0.7Chart context menuAccess Area Distribution其他: 30.2 %其他: 30.2 %China: 0.2 %China: 0.2 %Korea Republic of: 0.2 %Korea Republic of: 0.2 %三明: 0.2 %三明: 0.2 %上海: 1.3 %上海: 1.3 %丽水: 0.2 %丽水: 0.2 %北京: 23.1 %北京: 23.1 %台州: 0.2 %台州: 0.2 %天津: 0.2 %天津: 0.2 %成都: 0.3 %成都: 0.3 %杭州: 1.7 %杭州: 1.7 %武汉: 0.5 %武汉: 0.5 %沈阳: 0.3 %沈阳: 0.3 %济南: 0.2 %济南: 0.2 %深圳: 0.3 %深圳: 0.3 %湖州: 0.2 %湖州: 0.2 %澳大利亚新南威尔士悉尼: 0.3 %澳大利亚新南威尔士悉尼: 0.3 %玉溪: 0.3 %玉溪: 0.3 %珀斯: 0.7 %珀斯: 0.7 %珠海: 0.2 %珠海: 0.2 %芒廷维尤: 9.4 %芒廷维尤: 9.4 %蚌埠: 0.2 %蚌埠: 0.2 %西宁: 26.6 %西宁: 26.6 %西安: 0.2 %西安: 0.2 %贵阳: 1.2 %贵阳: 1.2 %运城: 0.2 %运城: 0.2 %郑州: 0.2 %郑州: 0.2 %金华: 0.3 %金华: 0.3 %长沙: 0.8 %长沙: 0.8 %青岛: 0.3 %青岛: 0.3 %其他ChinaKorea Republic of三明上海丽水北京台州天津成都杭州武汉沈阳济南深圳湖州澳大利亚新南威尔士悉尼玉溪珀斯珠海芒廷维尤蚌埠西宁西安贵阳运城郑州金华长沙青岛Highcharts.com
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Orthogonal design of formula optimization for Huanggui enema

Abstract: Objective To choose the best formula for Huanggui enema. Methods The orthogonal test was used to optimize formula,and the clearance index in mice and antibacterial action in vitro were observation index.The best formula was designed according to the result of this study. Results The formula is: Rhizoma Coptids 60 g,Cortex phellodendn 180 g,Ramulus Cinnamoni 120 g,Radixet Rhizoma Rhei 48 g per 1 000 ml.The clearance index in mice is greater 20%,diameter of inhibition zone is greater 35 mm. Conclusion The optimized formula is reasonable and provided an experimental basis for clinical application.

DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.
Citation: DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.

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