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DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.
Citation:
DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.
Orthogonal design of formula optimization for Huanggui enema
Wuxi Maternal and Child Health Hospital,Wuxi 214002,China
Received Date: 2009-11-04
Rev Recd Date:
2010-01-22
Abstract
Objective To choose the best formula for Huanggui enema. Methods The orthogonal test was used to optimize formula,and the clearance index in mice and antibacterial action in vitro were observation index.The best formula was designed according to the result of this study. Results The formula is: Rhizoma Coptids 60 g,Cortex phellodendn 180 g,Ramulus Cinnamoni 120 g,Radixet Rhizoma Rhei 48 g per 1 000 ml.The clearance index in mice is greater 20%,diameter of inhibition zone is greater 35 mm. Conclusion The optimized formula is reasonable and provided an experimental basis for clinical application.
Abstract: Objective To choose the best formula for Huanggui enema. Methods The orthogonal test was used to optimize formula,and the clearance index in mice and antibacterial action in vitro were observation index.The best formula was designed according to the result of this study. Results The formula is: Rhizoma Coptids 60 g,Cortex phellodendn 180 g,Ramulus Cinnamoni 120 g,Radixet Rhizoma Rhei 48 g per 1 000 ml.The clearance index in mice is greater 20%,diameter of inhibition zone is greater 35 mm. Conclusion The optimized formula is reasonable and provided an experimental basis for clinical application.
DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.
Citation:
DENG Li-qin, ZHANG Yan. Orthogonal design of formula optimization for Huanggui enema[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 203-205.