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LAI Wei, YANG Yang, ZHAN Qin, SUN Lian-na, CHEN Wan-sheng. Study on chemical constituents of Semen Allii Fistulosi[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(1): 38-39,57.
Citation:
LAI Wei, YANG Yang, ZHAN Qin, SUN Lian-na, CHEN Wan-sheng. Study on chemical constituents of Semen Allii Fistulosi[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(1): 38-39,57.
Study on chemical constituents of Semen Allii Fistulosi
School of Pharmacy, Second Military Medical University, Shanghai 200433, China; Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
2.
Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
3.
School of Pharmacy, Second Military Medical University, Shanghai 200433, China
Received Date: 2008-11-06
Abstract
Objective : To study the chemical constituents of Semen Allii Fistulosi. Methods :Isolation and purification were carried out by macroporous absorption resin,silica gel,Sephadex LH-20 and RP-silica.The compounds of Semem Allii Fistulosi were identified and elucidated by spectral and chemical methods. Results :Seven compounds were obtained from water extract of Semen Allii Fistulosi and their structures were determined as adenosine(Ⅰ),2,3,4,5,6-pentahydroxyhexanoic acid(Ⅱ),2-methoxyhydroquinone(Ⅲ),S-(cis-1-propenyl)-L-cysteine(Ⅳ),S-(trans-1-propenyl)-L-cysteine(Ⅴ),trans-hinokiresinol(Ⅵ),and β-sitosterol(Ⅶ). Conclusion :All the compounds are found in Semen Allii Fistulosi for the first time,and compound Ⅵ is found in Allium for the first time.
1. School of Pharmacy, Second Military Medical University, Shanghai 200433, China; Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
2. Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
3. School of Pharmacy, Second Military Medical University, Shanghai 200433, China
Abstract: Objective : To study the chemical constituents of Semen Allii Fistulosi. Methods :Isolation and purification were carried out by macroporous absorption resin,silica gel,Sephadex LH-20 and RP-silica.The compounds of Semem Allii Fistulosi were identified and elucidated by spectral and chemical methods. Results :Seven compounds were obtained from water extract of Semen Allii Fistulosi and their structures were determined as adenosine(Ⅰ),2,3,4,5,6-pentahydroxyhexanoic acid(Ⅱ),2-methoxyhydroquinone(Ⅲ),S-(cis-1-propenyl)-L-cysteine(Ⅳ),S-(trans-1-propenyl)-L-cysteine(Ⅴ),trans-hinokiresinol(Ⅵ),and β-sitosterol(Ⅶ). Conclusion :All the compounds are found in Semen Allii Fistulosi for the first time,and compound Ⅵ is found in Allium for the first time.
LAI Wei, YANG Yang, ZHAN Qin, SUN Lian-na, CHEN Wan-sheng. Study on chemical constituents of Semen Allii Fistulosi[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(1): 38-39,57.
Citation:
LAI Wei, YANG Yang, ZHAN Qin, SUN Lian-na, CHEN Wan-sheng. Study on chemical constituents of Semen Allii Fistulosi[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(1): 38-39,57.