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Volume 26 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (4): 261-263,277

GUAN Qing-xiang, LIN Tian-mu, WANG En-si. The formula optimization of delavirdine mesylate dispersible tablets by orthogonal design test[J]. Journal of Pharmaceutical Practice and Service, 2008, (4): 261-263,277.
Citation: GUAN Qing-xiang, LIN Tian-mu, WANG En-si. The formula optimization of delavirdine mesylate dispersible tablets by orthogonal design test[J]. Journal of Pharmaceutical Practice and Service, 2008, (4): 261-263,277.
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The formula optimization of delavirdine mesylate dispersible tablets by orthogonal design test

  • 1.

    School of Pharmacy,Jilin University,Changchun 130021,China;School of Life Science,Jilin University,Changchun 130021,China

  • 2.

    School of Life Science,Jilin University,Changchun 130021,China

  • Received Date: 2008-04-28
  • Objective: To optimize the formula and prepare delavirdine mesylate dispersible tablets. Methods: The formula of delavirdine mesylate dispersible tablet was optimized in term of disintegrating time by orthogonal design test.The dissolution rates of the principal agent in dispersible tablets were determined. Results: The optimized dispersible tablets had fine appearance and disintegrated in 3 min,and the suspension screened through the 710μm mesh.The dissolution rates of the dispersible tablets were similar in 3 bat- ches formulation. Conclusion:: The prepared delavirdine mesylate dispersible tablet was reasonable in formula,feasible in technology and was accorded with the quality standards.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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The formula optimization of delavirdine mesylate dispersible tablets by orthogonal design test

  • 1. School of Pharmacy,Jilin University,Changchun 130021,China;School of Life Science,Jilin University,Changchun 130021,China
  • 2. School of Life Science,Jilin University,Changchun 130021,China
  • Received Date: 2008-04-28

Abstract: Objective: To optimize the formula and prepare delavirdine mesylate dispersible tablets. Methods: The formula of delavirdine mesylate dispersible tablet was optimized in term of disintegrating time by orthogonal design test.The dissolution rates of the principal agent in dispersible tablets were determined. Results: The optimized dispersible tablets had fine appearance and disintegrated in 3 min,and the suspension screened through the 710μm mesh.The dissolution rates of the dispersible tablets were similar in 3 bat- ches formulation. Conclusion:: The prepared delavirdine mesylate dispersible tablet was reasonable in formula,feasible in technology and was accorded with the quality standards.

GUAN Qing-xiang, LIN Tian-mu, WANG En-si. The formula optimization of delavirdine mesylate dispersible tablets by orthogonal design test[J]. Journal of Pharmaceutical Practice and Service, 2008, (4): 261-263,277.
Citation: GUAN Qing-xiang, LIN Tian-mu, WANG En-si. The formula optimization of delavirdine mesylate dispersible tablets by orthogonal design test[J]. Journal of Pharmaceutical Practice and Service, 2008, (4): 261-263,277.
shu

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