Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 26 Issue 3
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (3): 217-219

GU Wei-feng, PIAO Shu-juan, ZHANG Chun. Determination of salicylic acid and tetracation hydrochloride in Compound onychomycosis cream by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (3): 217-219.
Citation: GU Wei-feng, PIAO Shu-juan, ZHANG Chun. Determination of salicylic acid and tetracation hydrochloride in Compound onychomycosis cream by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (3): 217-219.
shu

Determination of salicylic acid and tetracation hydrochloride in Compound onychomycosis cream by HPLC

  • Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003

  • Received Date: 2007-07-05
  • Objective: To establish a HPLC method for the determination of salicylic acid and tetracation hydrochloride in compound onychomycosis cream. Methods: Agilent-C18(4.6 mm×150 mm,5 μm) column was used with a mobile phase of methanol-water-phosphoric(50500.04) and a flow rate of l.0 mL/min,at the detection wavelength of 313 nm. Results: This method showed good linear relation(r= 0.999 9) in the range of 82.00～410.00 μg/mL for salicylic acid,and 5.00～25.00 μg/mL for tetracation hydrochloride.The average recoveries were 99.80% and 99.75%,with the relative standard deviation of 1.68% and 1.36%,respectively. Conclusion: The method is simple,quick,accurate and suitable for the quality control of compound onychomycosis cream.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2051) PDF downloads(1038) Cited by()

Related
Proportional views

Determination of salicylic acid and tetracation hydrochloride in Compound onychomycosis cream by HPLC

  • Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003
  • Received Date: 2007-07-05

Abstract: Objective: To establish a HPLC method for the determination of salicylic acid and tetracation hydrochloride in compound onychomycosis cream. Methods: Agilent-C18(4.6 mm×150 mm,5 μm) column was used with a mobile phase of methanol-water-phosphoric(50500.04) and a flow rate of l.0 mL/min,at the detection wavelength of 313 nm. Results: This method showed good linear relation(r= 0.999 9) in the range of 82.00～410.00 μg/mL for salicylic acid,and 5.00～25.00 μg/mL for tetracation hydrochloride.The average recoveries were 99.80% and 99.75%,with the relative standard deviation of 1.68% and 1.36%,respectively. Conclusion: The method is simple,quick,accurate and suitable for the quality control of compound onychomycosis cream.

GU Wei-feng, PIAO Shu-juan, ZHANG Chun. Determination of salicylic acid and tetracation hydrochloride in Compound onychomycosis cream by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (3): 217-219.
Citation: GU Wei-feng, PIAO Shu-juan, ZHANG Chun. Determination of salicylic acid and tetracation hydrochloride in Compound onychomycosis cream by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2008, (3): 217-219.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return