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Volume 26 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2008  >  (1): 35-37

GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37.
Citation: GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37.
shu

Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry

  • 1.

    Department of Pharmacy,Central Hospital of Yiyang of Hunan Province, Yiyang 413000,China

  • 2.

    Department of Pharmacy,Central Hospital of Yiyang of Hunan Province, Yiyang 413000,China

  • Received Date: 2007-12-11
  • Rev Recd Date: 2007-01-15
  • Objective: To establish a new method for the determination of rabeprazole. Methods: Anodic adsorptive voltammetry with a carbon paste electeode(CPE) was used. Rabeprazole was concentrated on the electrode and determined by adsorptive voltammetry in supporting solution of 1.8 mol/L H2SO4. Results: The anthodic peak potential of raberazole was at 0.498 V(vs.SCE). The peak currents were linear with the concentration of rabeprazole over the range of 4.15×10-7～3.73×10--6mol/L, with the detection limit 6.705×10--11 mol/L. Conclusion: This method is suitable for the determination of rabeprazole, and it is covenient and accurate.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry

  • 1. Department of Pharmacy,Central Hospital of Yiyang of Hunan Province, Yiyang 413000,China
  • 2. Department of Pharmacy,Central Hospital of Yiyang of Hunan Province, Yiyang 413000,China
  • Received Date: 2007-12-11
  • Rev Recd Date: 2007-01-15

Abstract: Objective: To establish a new method for the determination of rabeprazole. Methods: Anodic adsorptive voltammetry with a carbon paste electeode(CPE) was used. Rabeprazole was concentrated on the electrode and determined by adsorptive voltammetry in supporting solution of 1.8 mol/L H2SO4. Results: The anthodic peak potential of raberazole was at 0.498 V(vs.SCE). The peak currents were linear with the concentration of rabeprazole over the range of 4.15×10-7～3.73×10--6mol/L, with the detection limit 6.705×10--11 mol/L. Conclusion: This method is suitable for the determination of rabeprazole, and it is covenient and accurate.

GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37.
Citation: GUO Li-min, ZHONG Shi-hua, LI Wei, HUANG Ye-ju. Determination of rabeprazole at a carbon paste electrode by anodic adsorptive voltammetry[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 35-37.
shu

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