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Volume 23 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2005  >  (6): 342-344

Su Juan, Fu Peng, Zhang Wei-dong, Liu Run-hui, Xu Xi-ke, Zhang Chuan. Experimenntal study on extracts of Hypericum japonicum in liver-protective effect[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 342-344.
Citation: Su Juan, Fu Peng, Zhang Wei-dong, Liu Run-hui, Xu Xi-ke, Zhang Chuan. Experimenntal study on extracts of Hypericum japonicum in liver-protective effect[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 342-344.
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Experimenntal study on extracts of Hypericum japonicum in liver-protective effect

  • School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • Received Date: 2005-09-22
  • Objective To study the protecting effects of extracts of the Hypericum japonicum Thunb. for the acute liver injury in rats. Methods The extracts of the Hypericum japonicum Thunb. were intraperitoneally given to every SD rat with acute liver injury induced by D-galactoasmine. It was detected that the activities of ALT and AST by using colorimetric method. Results The ethanol extract and ethyl acetate fraction of the Hypericum japonicum Thunb. significantly reduced acute liver injury induced by D-galactoasmine, by means of decreasing ALT and AST in serum. Conclusion The ethanol extract and ethyl acetate fraction of the Hypericum japonicum Thunb. have protecting effects for liver.
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Experimenntal study on extracts of Hypericum japonicum in liver-protective effect

  • School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received Date: 2005-09-22

Abstract: Objective To study the protecting effects of extracts of the Hypericum japonicum Thunb. for the acute liver injury in rats. Methods The extracts of the Hypericum japonicum Thunb. were intraperitoneally given to every SD rat with acute liver injury induced by D-galactoasmine. It was detected that the activities of ALT and AST by using colorimetric method. Results The ethanol extract and ethyl acetate fraction of the Hypericum japonicum Thunb. significantly reduced acute liver injury induced by D-galactoasmine, by means of decreasing ALT and AST in serum. Conclusion The ethanol extract and ethyl acetate fraction of the Hypericum japonicum Thunb. have protecting effects for liver.

Su Juan, Fu Peng, Zhang Wei-dong, Liu Run-hui, Xu Xi-ke, Zhang Chuan. Experimenntal study on extracts of Hypericum japonicum in liver-protective effect[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 342-344.
Citation: Su Juan, Fu Peng, Zhang Wei-dong, Liu Run-hui, Xu Xi-ke, Zhang Chuan. Experimenntal study on extracts of Hypericum japonicum in liver-protective effect[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 342-344.
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