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ZHAO Nan, TANG Zhen, LI Jian, WANG Yan-ping, WANG Wei-dong, XIE Hua-tong, YAN Xiao-peng. A new solid dosage form:orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 326-330.
Citation:
ZHAO Nan, TANG Zhen, LI Jian, WANG Yan-ping, WANG Wei-dong, XIE Hua-tong, YAN Xiao-peng. A new solid dosage form:orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 326-330.
A new solid dosage form:orally disintegrating tablets
The Pharmacy College of Yan Bian University, Yanji 133000, China
2.
No. 208 Hospital of PLA, Changchun 130062, China
Received Date: 2005-08-02
Abstract
A new oral solid dosage form of rapidly disintegrating tablets have attracted increasing attention by its novel characteristics, such as fast disintegration, rapid absorption, high bioavailability, convient taking and so on. The dosage form brings great benefits to children and elderly people, especially those who have difficulities in swallowing. This article mainly describes the fast disintegration mechanism of orally disintegrating tablets, some preparation methods and excipients. The key quality properties are disintegrating time and dissolution. Finally, the article introduces some products that have already come into market.
Abstract: A new oral solid dosage form of rapidly disintegrating tablets have attracted increasing attention by its novel characteristics, such as fast disintegration, rapid absorption, high bioavailability, convient taking and so on. The dosage form brings great benefits to children and elderly people, especially those who have difficulities in swallowing. This article mainly describes the fast disintegration mechanism of orally disintegrating tablets, some preparation methods and excipients. The key quality properties are disintegrating time and dissolution. Finally, the article introduces some products that have already come into market.
ZHAO Nan, TANG Zhen, LI Jian, WANG Yan-ping, WANG Wei-dong, XIE Hua-tong, YAN Xiao-peng. A new solid dosage form:orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 326-330.
Citation:
ZHAO Nan, TANG Zhen, LI Jian, WANG Yan-ping, WANG Wei-dong, XIE Hua-tong, YAN Xiao-peng. A new solid dosage form:orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2005, (6): 326-330.