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Volume 22 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2004  >  (4): 224-225

LI Bing. Studies on compatible stability between cefotaxime sodium and oflaxacin injection[J]. Journal of Pharmaceutical Practice and Service, 2004, (4): 224-225.
Citation: LI Bing. Studies on compatible stability between cefotaxime sodium and oflaxacin injection[J]. Journal of Pharmaceutical Practice and Service, 2004, (4): 224-225.
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Studies on compatible stability between cefotaxime sodium and oflaxacin injection

  • Department of Pharmacy, Anqing Municipal Hospital, Anqing 246003, China

  • Received Date: 2003-01-07
  • Objective To study the compatible stability between cefotaxime sodium and oflaxacin injection. Methods The UVmethod for determination of cefotaxime and ofloxacin in their mixed solution was established, by which they were assayed when the mixed solution was set at 24℃ during 8h. The appearance, pH values and UV spectrum of the mixed solution were also examined. Results The appearance, pH values and UV spectrum of the mixed solution didn't change obviously during 4h. The assay values for cefotaxime sodium and ofloxacin 6h late were higher than 4h. The UV spectrum of the mixed solution changed obviously 8h late. Conclusion They were stable when cefotaxime was dissolved in oflaxacin injection, suggesting oflaxacin injection containing cefotaxime should be used up within 4h.
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Studies on compatible stability between cefotaxime sodium and oflaxacin injection

  • Department of Pharmacy, Anqing Municipal Hospital, Anqing 246003, China
  • Received Date: 2003-01-07

Abstract: Objective To study the compatible stability between cefotaxime sodium and oflaxacin injection. Methods The UVmethod for determination of cefotaxime and ofloxacin in their mixed solution was established, by which they were assayed when the mixed solution was set at 24℃ during 8h. The appearance, pH values and UV spectrum of the mixed solution were also examined. Results The appearance, pH values and UV spectrum of the mixed solution didn't change obviously during 4h. The assay values for cefotaxime sodium and ofloxacin 6h late were higher than 4h. The UV spectrum of the mixed solution changed obviously 8h late. Conclusion They were stable when cefotaxime was dissolved in oflaxacin injection, suggesting oflaxacin injection containing cefotaxime should be used up within 4h.

LI Bing. Studies on compatible stability between cefotaxime sodium and oflaxacin injection[J]. Journal of Pharmaceutical Practice and Service, 2004, (4): 224-225.
Citation: LI Bing. Studies on compatible stability between cefotaxime sodium and oflaxacin injection[J]. Journal of Pharmaceutical Practice and Service, 2004, (4): 224-225.
shu

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