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LIU Mei-juan, LOU Ping. Determination of ephedrine hydrochloride in kegan nasal drops by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 369-370.
Citation:
LIU Mei-juan, LOU Ping. Determination of ephedrine hydrochloride in kegan nasal drops by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 369-370.
Determination of ephedrine hydrochloride in kegan nasal drops by HPLC
Linyi hospitaL for heath protection of woman and child, Linyi 276003, China
2.
Linyi Institute for Drug ControL
Received Date: 2003-10-28
Abstract
OBJECTIVE To develop a method for the determination of ephedrine hydrochloride in kegan nasal drops by HPLC. METHODS The chromatographic condition included ODS column and the mobile phase consisting of 0.01 mol/L KH2PO4 solution-acetonitrile(40:60).The detection wavelengthwas at 215nm,flow rate at 1.0mL/min. RESULTS:The calibration curve was linear over the rage of 40-96μg/mL. The average recovery was 96.1%.The method precision(RSD%)was 1.2%(n=5).CONCLUSION The method was convenient and accurate for the quality control of the preparation.
Abstract: OBJECTIVE To develop a method for the determination of ephedrine hydrochloride in kegan nasal drops by HPLC. METHODS The chromatographic condition included ODS column and the mobile phase consisting of 0.01 mol/L KH2PO4 solution-acetonitrile(40:60).The detection wavelengthwas at 215nm,flow rate at 1.0mL/min. RESULTS:The calibration curve was linear over the rage of 40-96μg/mL. The average recovery was 96.1%.The method precision(RSD%)was 1.2%(n=5).CONCLUSION The method was convenient and accurate for the quality control of the preparation.
LIU Mei-juan, LOU Ping. Determination of ephedrine hydrochloride in kegan nasal drops by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 369-370.
Citation:
LIU Mei-juan, LOU Ping. Determination of ephedrine hydrochloride in kegan nasal drops by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 369-370.