Determination of dihydroartemisinin of compound dihydroartemisinin tablets by tri-wavelength spectrophotosmetry

Key words: 
• compound dihydroartemisinin tablets /
• trii-wavelength spectrophotometry /
• dihydroartemisinin

Abstract: OBJECTIVE To establish the method of determination of content of compound dihydroartemisinin tablets. METHODS Detected at 250nm, with baseline wavelength 1 at 271nm and baseline wavelength 2 at 301nm.301 nm. RESULTS:Within 6-30μg·mL^-1,DHA had a good linearity(r =0.99992,n=10).The average recoverty was 101.7%, with the RSD of 0.66%(n=9).CONCLUSION Tri-wavelength spectrophotosmetry can directly detected without the disturbance of trimethoprim and piperaquine phosphate,this method was simple,rapid,accurate.