Clinical efficacy on chronic hepatitis B treated by lamivudine combination with oxymatrine
- Received Date: 2002-04-12
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Key words:
- lamivudine /
- oxymatrine /
- chronic hepatitis B /
- side effects
Abstract: OBJECTIVE To study the efficacy and safety of lamivudine combination with oxymatrine in treating chronic hepatitis B.METHODS 67 patients were randomly divided into 2 groups.36 patients as a treatment group received 100mg·d-1,po,lamivudine combination with 600mg·d-1,im oxymatrine for 3 months.31 patients as a control group was treated only with routine therapy.RESULTS After completion of therapy,the change of liver function and mark of HBVM were observed.In the two groups,the recovery rate of ALT was 90.2% and 75.3%,the negative rate of HBeAg was 33.4% and 16.1%.The efficacy of the treatment group was higher than that of control group.(P<0.05).Side effects had not been found.CONCLUSION lamivudine combination with oxymatrine can improve the liver function and inhibit HBV.
Citation: | GU Jing-jing, Tian Gui-zhen. Clinical efficacy on chronic hepatitis B treated by lamivudine combination with oxymatrine[J]. Journal of Pharmaceutical Practice and Service, 2003, (1): 3-4. |