Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

SHANG Bei-cheng, XU Gui-li, TANG Bing, FANG Li-sha, LIU Jiang, DUAN Hui-qiong, ZHAO Xing-min. The enhancement effect of dipentene in the transdermal absorption of ketoconazole[J]. Journal of Pharmaceutical Practice and Service, 2002, (2): 84-86.
Citation: SHANG Bei-cheng, XU Gui-li, TANG Bing, FANG Li-sha, LIU Jiang, DUAN Hui-qiong, ZHAO Xing-min. The enhancement effect of dipentene in the transdermal absorption of ketoconazole[J]. Journal of Pharmaceutical Practice and Service, 2002, (2): 84-86.

The enhancement effect of dipentene in the transdermal absorption of ketoconazole

  • Received Date: 2001-05-14
  • OBJECTIVE To study the enhancing effect of dipentene in the transdermal absorption of ketoconazol. METHODS The diffusion of ketoconazole acrossed excised mouse skin was determined in vitro using the side-by-side diffusion cells,to compare the enhancement effect of dipentene with azone at difference concentrations in the transdermal absorption of ketoconazole.RESULTS The sequence of enhancements at difference concentrations of dipentene are as follows:3%dipentene> 2%dipentene> 3%azone> 1%dipentene.CONCLUSION It was showed that various concentrations of transdermal enhancers could promote absorption of ketoconazole in different degrees and 3% dipentene was the most effective.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(2232) PDF downloads(982) Cited by()

Related
Proportional views

The enhancement effect of dipentene in the transdermal absorption of ketoconazole

Abstract: OBJECTIVE To study the enhancing effect of dipentene in the transdermal absorption of ketoconazol. METHODS The diffusion of ketoconazole acrossed excised mouse skin was determined in vitro using the side-by-side diffusion cells,to compare the enhancement effect of dipentene with azone at difference concentrations in the transdermal absorption of ketoconazole.RESULTS The sequence of enhancements at difference concentrations of dipentene are as follows:3%dipentene> 2%dipentene> 3%azone> 1%dipentene.CONCLUSION It was showed that various concentrations of transdermal enhancers could promote absorption of ketoconazole in different degrees and 3% dipentene was the most effective.

SHANG Bei-cheng, XU Gui-li, TANG Bing, FANG Li-sha, LIU Jiang, DUAN Hui-qiong, ZHAO Xing-min. The enhancement effect of dipentene in the transdermal absorption of ketoconazole[J]. Journal of Pharmaceutical Practice and Service, 2002, (2): 84-86.
Citation: SHANG Bei-cheng, XU Gui-li, TANG Bing, FANG Li-sha, LIU Jiang, DUAN Hui-qiong, ZHAO Xing-min. The enhancement effect of dipentene in the transdermal absorption of ketoconazole[J]. Journal of Pharmaceutical Practice and Service, 2002, (2): 84-86.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return