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Volume 18 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2000  >  (5): 280-283

ZHENG Yi-nan, XU Bao-jun, . Studies on Constituents in the leaves of Salix matsdana[J]. Journal of Pharmaceutical Practice and Service, 2000, (5): 280-283.
Citation: ZHENG Yi-nan, XU Bao-jun, . Studies on Constituents in the leaves of Salix matsdana[J]. Journal of Pharmaceutical Practice and Service, 2000, (5): 280-283.
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Studies on Constituents in the leaves of Salix matsdana

  • Received Date: 2000-08-28
  • From the leaves of Salix matsdana,three known compounds,apigenin-7-O-β-D-glucopyranuronide(Ⅰ),luteolin-7-O-β-D-glucopyranuronide(Ⅱ),were isolated at first in the Salix spp.Other compound(Ⅲ),was isolated in the leaves of Salix matsdana and proposed as p-phenol-methyl-O-β-D-glycoside, Furthermore, we studied on effect of arachidonic acid metabolism in rat platelets by compoundⅠ、Ⅱ and Ⅲ with radio-chromatography and found that these compounds can significantly inhibit the production of 12-HETE(12-hydroxy-5,8,10,14-eicosatetraenoic acid), which can induced allergy and atheroselero-sis.The production of apigenin-7-O-β-D-glucopyranuroide being hydrolyzed was apigenin, which can inhibit not only 12-HETE but also TXB2(thromboxane B2) which can induce platelet aggregation.
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Studies on Constituents in the leaves of Salix matsdana

  • Received Date: 2000-08-28

Abstract: From the leaves of Salix matsdana,three known compounds,apigenin-7-O-β-D-glucopyranuronide(Ⅰ),luteolin-7-O-β-D-glucopyranuronide(Ⅱ),were isolated at first in the Salix spp.Other compound(Ⅲ),was isolated in the leaves of Salix matsdana and proposed as p-phenol-methyl-O-β-D-glycoside, Furthermore, we studied on effect of arachidonic acid metabolism in rat platelets by compoundⅠ、Ⅱ and Ⅲ with radio-chromatography and found that these compounds can significantly inhibit the production of 12-HETE(12-hydroxy-5,8,10,14-eicosatetraenoic acid), which can induced allergy and atheroselero-sis.The production of apigenin-7-O-β-D-glucopyranuroide being hydrolyzed was apigenin, which can inhibit not only 12-HETE but also TXB2(thromboxane B2) which can induce platelet aggregation.

ZHENG Yi-nan, XU Bao-jun, . Studies on Constituents in the leaves of Salix matsdana[J]. Journal of Pharmaceutical Practice and Service, 2000, (5): 280-283.
Citation: ZHENG Yi-nan, XU Bao-jun, . Studies on Constituents in the leaves of Salix matsdana[J]. Journal of Pharmaceutical Practice and Service, 2000, (5): 280-283.
shu

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