Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone
- Received Date: 1999-10-22
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Key words:
- subacute thyroditis /
- thyroid /
- dexamethasone /
- topical therapy
Abstract: OBJECTIVE To investigate the efficacy and safety of topical intrathyroid injection of dexamethasone in the patients with subacute thyroiditis.METHODS Twenty patients with subacute thyroiditis were divided randomly into two groups.10 Patients (group A) were treated with topical intrathyroid injection of dexamethasone(5mg/ml,twice perweek),10 Patients (group B)were treated with prednisone 30 mg/d orally.Clinical outcomes of two groups are compared after 2 weeks,4 weeks and 8 weeks.RESULTS Curative rate of group A and group B after 8 weeks were 90% and 100% respectively and there were no significant difference(P>0.25).Duration of therapy were(5.6±2.1) weeks in group A and (8.2±1.8) weeks in group B respectively and there were significant difference (P<0.05).No adverse reactions occurred in both groups.CONCLUSIONS:Topical injection of dexamethasone in patients with subacute thyroiditis improves the symptoms rapidly and shorten the course of disease,so it is highly effective and safe.
| Citation: | ZHANG Hui, GU Ming-jun, LIU Zhi-min, Shi, Yong-quan. Theraping the patients with subacute thyroiditis in topical intrathyroid injection of dexamethasone[J]. Journal of Pharmaceutical Practice and Service, 2000, (3): 134-136.
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