Determination of indometacin in glucosamine indometacin enteric coated tablets by HPLC

WANG Qiong-fen; MEI Hong-hui

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Volume 18 Issue 2

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2000 > (2): 91-92,95

WANG Qiong-fen, MEI Hong-hui. Determination of indometacin in glucosamine indometacin enteric coated tablets by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 91-92,95.

Citation:

WANG Qiong-fen, MEI Hong-hui. Determination of indometacin in glucosamine indometacin enteric coated tablets by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 91-92,95.

Determination of indometacin in glucosamine indometacin enteric coated tablets by HPLC

Received Date: 1999-12-06

Abstract

OBJECTIVE To establish a method for the determination the indometacin content in glucosamine indometacin enteric-coated tablets by HPLC.METHODS Using SPHERI-5 RP-18 column,with methanol-water-acetonitrile-phosphoric acid(60:25:15:0.04) as the mobile.RESULTS An excellent linear relationship was obtained between the peak area and the concentration with the range of 10～60μg/ml.The average recoverary was 99.56%,the RSD was 0.65%.CONCLUSION This method is accurate,quick and reproducible.
- indometacin,
- glucosamine indometacin,
- HPLC,
- determination
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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