Study on the dissolution of diflunisal capsules

Lin fang; Wang Shenghao; Wang Guoqiang; Han Jinwen

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Volume 17 Issue 6

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Article Navigation > Journal of Pharmaceutical Practice and Service > 1999 > (6): 339-341

Lin fang, Wang Shenghao, Wang Guoqiang, Han Jinwen. Study on the dissolution of diflunisal capsules[J]. Journal of Pharmaceutical Practice and Service, 1999, (6): 339-341.

Citation:

Lin fang, Wang Shenghao, Wang Guoqiang, Han Jinwen. Study on the dissolution of diflunisal capsules[J]. Journal of Pharmaceutical Practice and Service, 1999, (6): 339-341.

Study on the dissolution of diflunisal capsules

Institute of Materia Medica, Zhejiang Academy of Medical Sciences, Hangzhou 310013

Received Date: 1999-04-19

Abstract

OBJECTIVE The vitro release of diflunisal capsules were compared with the tablets (imported,made by Merck Corporation). METHODS Referring to the USP ⅩⅩⅢ,the dissolution and the content of two kinds of dosage forms containing diflunisal were determined by UV spectropholometer respectively. RESULTS The average recovery was 100.27%(RSD =0.62%).The in vitro release of capsules was faster that of diflunisal material and available tablets. T₈₀ of capsules was 12.8min vs.13.08min of tablets. CONCLUSION The rate of dissolution has no significance differences between the capsules and the imported tablets.
- diflunisal,
- capsule,
- tablet,
- dissolution
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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