Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 16 Issue 6
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1998  >  (6): 322-325

Liu Yuansheng, Sun Huikuan, Qiu Nengyong, Zhang Yanping. The protective effect of indapndde and verapamil in myocardial ischemia and reperfusion injury in rabbit Langendorff heart[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 322-325.
Citation: Liu Yuansheng, Sun Huikuan, Qiu Nengyong, Zhang Yanping. The protective effect of indapndde and verapamil in myocardial ischemia and reperfusion injury in rabbit Langendorff heart[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 322-325.
shu

The protective effect of indapndde and verapamil in myocardial ischemia and reperfusion injury in rabbit Langendorff heart

  • Department of Cardiovascular Medicine, First Affiliated Hospital, Inner Mongolia Medical College, Huhhot 010050

  • The animal medels of isolated myochoial pehschemic reperfusion injury in rabbits using Langendorff apparatus were used to inquire into the protective effect of indapamide and verapamil. Methods: Twenty - one male rabbits were randomly divided into three groups (n=7 in each): control group, verapamil group and indapamide group. Isolated heaxts were reperfused after 40 min of global no - flow ischemia, Reperfusion oulflow fluid were collected at 15 min,30 min 60 min and 300 min after postischemic reperfusion in order to measure SOD and MDA. Coronary flow, coronary resistance and platelet aggregation rate were tested. Results and Conclusion: The protective effect of indapamide and addition,apamil amy include: (1 )antioxide and free - radical scavenging; (2) dilating coroner artery. In addition, indapamide can decrease platelet aggregation rate.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2160) PDF downloads(479) Cited by()

Related
Proportional views

The protective effect of indapndde and verapamil in myocardial ischemia and reperfusion injury in rabbit Langendorff heart

  • Department of Cardiovascular Medicine, First Affiliated Hospital, Inner Mongolia Medical College, Huhhot 010050

Abstract: The animal medels of isolated myochoial pehschemic reperfusion injury in rabbits using Langendorff apparatus were used to inquire into the protective effect of indapamide and verapamil. Methods: Twenty - one male rabbits were randomly divided into three groups (n=7 in each): control group, verapamil group and indapamide group. Isolated heaxts were reperfused after 40 min of global no - flow ischemia, Reperfusion oulflow fluid were collected at 15 min,30 min 60 min and 300 min after postischemic reperfusion in order to measure SOD and MDA. Coronary flow, coronary resistance and platelet aggregation rate were tested. Results and Conclusion: The protective effect of indapamide and addition,apamil amy include: (1 )antioxide and free - radical scavenging; (2) dilating coroner artery. In addition, indapamide can decrease platelet aggregation rate.

Liu Yuansheng, Sun Huikuan, Qiu Nengyong, Zhang Yanping. The protective effect of indapndde and verapamil in myocardial ischemia and reperfusion injury in rabbit Langendorff heart[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 322-325.
Citation: Liu Yuansheng, Sun Huikuan, Qiu Nengyong, Zhang Yanping. The protective effect of indapndde and verapamil in myocardial ischemia and reperfusion injury in rabbit Langendorff heart[J]. Journal of Pharmaceutical Practice and Service, 1998, (6): 322-325.
shu

    HTML

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return