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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 1997  >  (3): 154-157

He Li, He Jin. The absorption study of garlic oil and it's inclusion compound in small intestine of rats[J]. Journal of Pharmaceutical Practice and Service, 1997, (3): 154-157.
Citation: He Li, He Jin. The absorption study of garlic oil and it's inclusion compound in small intestine of rats[J]. Journal of Pharmaceutical Practice and Service, 1997, (3): 154-157.
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The absorption study of garlic oil and it's inclusion compound in small intestine of rats

  • 1.

    Shenyan Military General Hospital, Shenyang 110015

  • 2.

  • By the circulating in small intestine of rats, the absorbing behavior was compared between garlic oil and its inclusion compound with concentration of garlic oil as a examining index. After garlic oil and inclusion compound were circulated for 2.5 hour in the intestine, their absorption speed constants(Ka) were 0.9665h-1 and 0.2568h-1,respectively. Absorption halflife (t1/2) were 43.13 minutes and 2.65 hours, respectively. Absorption rates were 94.87%and 51.05%,respectively circulating of the compound in the intestine for 6 hours, absorption rates were about 80%.From the absorption curves, we knew that the absorption of the compound was slower, smoother and more permanent than that of garlic oil. The pathologicol findings were that inclusion compound could lower the irritation and toxicity of garlic oil to the intestine.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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The absorption study of garlic oil and it's inclusion compound in small intestine of rats

  • 1. Shenyan Military General Hospital, Shenyang 110015
  • 2. 

Abstract: By the circulating in small intestine of rats, the absorbing behavior was compared between garlic oil and its inclusion compound with concentration of garlic oil as a examining index. After garlic oil and inclusion compound were circulated for 2.5 hour in the intestine, their absorption speed constants(Ka) were 0.9665h-1 and 0.2568h-1,respectively. Absorption halflife (t1/2) were 43.13 minutes and 2.65 hours, respectively. Absorption rates were 94.87%and 51.05%,respectively circulating of the compound in the intestine for 6 hours, absorption rates were about 80%.From the absorption curves, we knew that the absorption of the compound was slower, smoother and more permanent than that of garlic oil. The pathologicol findings were that inclusion compound could lower the irritation and toxicity of garlic oil to the intestine.

He Li, He Jin. The absorption study of garlic oil and it's inclusion compound in small intestine of rats[J]. Journal of Pharmaceutical Practice and Service, 1997, (3): 154-157.
Citation: He Li, He Jin. The absorption study of garlic oil and it's inclusion compound in small intestine of rats[J]. Journal of Pharmaceutical Practice and Service, 1997, (3): 154-157.
shu

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